Results 91 to 100 of about 331,296 (302)

Deutscher Liederhort : Auswahl der vorzüglicheren Deutschen Volkslieder, nach Wort und Weise aus der Vorzeit und Gegenwart / von Erk, Ludwig / 1 Deutscher Liederhort : Auswahl der vorzüglicheren Deutschen Volkslieder, nach Wort und Weise aus der Vorzeit und Gegenwart

, 1893
ges. u. erl. von Ludwig Erk. Im Auftr. ... der Königlich Preußischen Regierung ... neubearb. u. fortges. v. Franz M.
Erk, Ludwig
core   +1 more source

Monitoring of bone matrix acidification by TRAP and ERK biomarkers in the chronic hypercholesterolemia male rats

Open Veterinary Journal
Background: Hypercholesterolemia is frequently linked to an elevated risk of cardiovascular diseases, including heart attacks and strokes. Additionally, it could be connected to a higher susceptibility to osteoporosis. Hypercholesterolemia can stimulate
Duaa Raad Abd-Al-Ameer, Wefak Albazi, Hayder Ali Muhammed   +2 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Macropinocytosis regulates cytokine expression through Erk signaling in LPS-stimulated macrophages

Cell Structure and Function
Macropinocytosis, a type of large-scale endocytosis process, is induced in macrophages by extracellular stimuli, including lipopolysaccharide (LPS).
Li Wang, Yanan Li, Yuxin He, Yuchen Fang, Hitomi Mimuro, Adam C. Midgley, Sei Yoshida   +6 more
doaj   +1 more source

Mechanoactive Biomaterials for Cell–Matrix Mechanotransduction

Advanced Materials, EarlyView.
The graphical abstract shows how individual triggers (force, light, or temperature) and combined optothermal or receptor‐targeted actuation induce material responses at the tissue, cellular, and receptor scales. Their spatial (global or focused) and temporal (continuous or cyclic) modulation determines the resulting mechanical output.
Yi‐Tung Lu, Alison E. John, Marc A. Fernández‐Yagüe   +2 more
wiley   +1 more source

Inhibition of ERK Dimerization Impairs RAS–ERK-Driven Tumorigenesis [PDF]

Cancer Discovery, 2015
Abstract Small-molecule blockade of ERK dimerization delays tumorigenesis driven by oncogenic RAS–ERK signaling.
openaire   +1 more source

Spatio-temporal activation of ERK.

, 2013
(A) Following location-specific activation of EGFR for indicated time, the spatio-temporal activation of ERK was determined by subcellular fractionation followed by immunoblotting with anti-pERK and anti-ERK antibodies as described in Experimental ...
Jennifer Jiang (307858), Peng Wu (210686), Zhixiang Wang (307861), Xinmei Chen (307859), Ping Wee (307857)   +4 more
core   +1 more source

Chemical Screening Identifies Danofloxacin as a Self‐Renewal Agonist of Embryonic Stem Cells through Alleviation of HDAC1‐Mediated Deacetylation of Tert and Prdm10

Advanced Science, EarlyView.
This study identified Danofloxacin as a novel supporter of the maintenance of mouse embryonic stem cell (ESC) pluripotency. It functions partially by inhibiting HDAC1, which increases specific histone acetylation marks and activates key genes like Tert and Prdm10.
Yan Zhang, Junxiang Ji, Baoxing Dong, Zhenhua Zhu, Xucheng Lv, Peng Chen, Wenqiang Liu, Min Zhou, Shou‐Dong Ye   +8 more
wiley   +1 more source

CCNY Accelerates Cylcin E Expression to Regulate the Proliferation of Laryngeal Carcinoma Cells via MEK/ERK Signaling Pathway

Cancer Management and Research, 2020
Xiaoting Zhao,1,2 Mei Jiang,1,2 Ziyu Wang,2 Xiaohong Chen,3 Hongzhen Wang,4 Wentao Yue,1 Chao Cai5,6 1Central Laboratory, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of ...
Zhao X, Jiang M, Wang Z, Chen X, Wang H, Yue W, Cai C   +6 more
doaj  

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source