Results 141 to 150 of about 1,847 (171)
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Current Medicinal Chemistry, 2017
Prior to senescence, erythrocytes may experience injury, which compromises their integrity and thus triggers suicidal erythrocyte death or eryptosis. This mechanism is characterised by cell shrinkage, cell membrane blebbing, and cell membrane phospholipid scrambling after phosphatidylserine exposure on the cell surface that is identified by macrophages,
Caterina Faggio, Marilena Briglia
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Prior to senescence, erythrocytes may experience injury, which compromises their integrity and thus triggers suicidal erythrocyte death or eryptosis. This mechanism is characterised by cell shrinkage, cell membrane blebbing, and cell membrane phospholipid scrambling after phosphatidylserine exposure on the cell surface that is identified by macrophages,
Caterina Faggio, Marilena Briglia
exaly +4 more sources
In Vitro Induction of Eryptosis by Uremic Toxins and Inflammation Mediators in Healthy Red Blood Cells [PDF]
Journal of Clinical Medicine, 2022 Eryptosis is the stress-induced RBC (red blood cell) death mechanism. It is known that eryptosis is largely influenced by plasma and blood composition, and that it is accelerated in patients affected by chronic kidney disease (CKD). The aim of this study
Grazia Maria, Claudio Ronco
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Eryptosis in Patients with Chronic Kidney Disease: A Possible Relationship with Oxidative Stress and Inflammatory Markers [PDF]
Journal of Clinical Medicine, 2022 Background. Eryptosis is the programmed death of red blood cells; it may contribute to worsening anemia in chronic kidney disease (CKD). In this clinical condition, different factors induce eryptosis, such as oxidative stress, energy depletion and uremic
Grazia Maria +2 more
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Mechanisms and Significance of Eryptosis
Antioxidants & Redox Signaling, 2006Suicidal death of erythrocytes (eryptosis) is characterized by cell shrinkage, membrane blebbing, activation of proteases, and phosphatidylserine exposure at the outer membrane leaflet. Exposed phosphatidylserine is recognized by macrophages that engulf and degrade the affected cells. Eryptosis is triggered by erythrocyte injury after several stressors,
Florian, Lang +4 more
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Eryptosis triggered by bismuth
BioMetals, 2008Bismuth is used for multiple industrial purposes and in the treatment of several gastrointestinal diseases. Untoward effects of bismuth include anemia, which could, in theory, result from suicidal erythrocyte death or eryptosis. Hallmarks of eryptosis are cell shrinkage and cell membrane scrambling with phosphatidylserine exposure at the cell surface ...
Manuel, Braun +3 more
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Apoptosis and eryptosis: similarities and differences
Apoptosis, 2023Eryptosis is a regulated cell death (RCD) of mature erythrocytes initially described as a counterpart of apoptosis for enucleated cells. However, over the recent years, a growing number of studies have emphasized certain differences between both cell death modalities.
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Induction of eryptosis by cyclosporine
Naunyn-Schmiedeberg's Archives of Pharmacology, 2006Side effects of cyclosporine treatment include anemia. Most recent studies have found that anemia may be caused by triggering of suicidal erythrocyte death (eryptosis), i.e. activation of an erythrocyte scramblase and phosphatidylserine exposure at the erythrocyte surface.
Olivier M, Niemoeller +8 more
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Eryptosis: a driver of anemia in chronic kidney disease
Current Opinion in Nephrology & Hypertension, 2023Purpose of review Anemia, characterized by a reduction in red blood cell (RBC) count or hemoglobin concentration, commonly accompanies chronic kidney disease (CKD), significantly impacting patients’ quality of life. This review delves into the multifaceted nature of anemia in CKD, with a focus on novel mechanisms, particularly ...
Bissinger, R., Qadri, S.M., Artunc, F.
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Eryptosis in lead-exposed workers
Toxicology and Applied Pharmacology, 2014Eryptosis is a physiological phenomenon in which old and damaged erythrocytes are removed from circulation. Erythrocytes incubated with lead have exhibited major eryptosis. In the present work we found evidence of high levels of eryptosis in lead exposed workers possibly via oxidation. Blood samples were taken from 40 male workers exposed to lead (mean
Itzel-Citlalli, Aguilar-Dorado +5 more
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Stimulation of eryptosis by aluminium ions
Toxicology and Applied Pharmacology, 2006Aluminium salts are utilized to impede intestinal phosphate absorption in chronic renal failure. Toxic side effects include anemia, which could result from impaired formation or accelerated clearance of circulating erythrocytes. Erythrocytes may be cleared secondary to suicidal erythrocyte death or eryptosis, which is characterized by cell shrinkage ...
Olivier M, Niemoeller +4 more
openaire +2 more sources