Results 151 to 160 of about 1,947 (173)

Induction of eryptosis by cyclosporine

Naunyn-Schmiedeberg's Archives of Pharmacology, 2006
Side effects of cyclosporine treatment include anemia. Most recent studies have found that anemia may be caused by triggering of suicidal erythrocyte death (eryptosis), i.e. activation of an erythrocyte scramblase and phosphatidylserine exposure at the erythrocyte surface.
Olivier M, Niemoeller, Ahmad, Akel, Philipp A, Lang, Philipp, Attanasio, Daniela S, Kempe, Tobias, Hermle, Malgorzata, Sobiesiak, Thomas, Wieder, Florian, Lang   +8 more
openaire   +2 more sources

Eryptosis in lead-exposed workers

Toxicology and Applied Pharmacology, 2014
Eryptosis is a physiological phenomenon in which old and damaged erythrocytes are removed from circulation. Erythrocytes incubated with lead have exhibited major eryptosis. In the present work we found evidence of high levels of eryptosis in lead exposed workers possibly via oxidation. Blood samples were taken from 40 male workers exposed to lead (mean
Itzel-Citlalli, Aguilar-Dorado, Gerardo, Hernández, Martha-Angelica, Quintanar-Escorza, María, Maldonado-Vega, Margarita, Rosas-Flores, José-Víctor, Calderón-Salinas   +5 more
openaire   +2 more sources

Eryptosis in autoimmune haemolytic anaemia

European Journal of Haematology, 2017
AbstractObjectiveHaemolysis and anaemia related to autoimmune haemolytic anaemia (AIHA) of warm type (wAIHA) and of cold type (cAIHA) are believed to be solely due to antibody and/or complement‐mediated destruction and clearance of red blood cells (RBCs). There is evidence that RBCs of affected patients may also undergo eryptosis, the suicidal death of
Thilo Bartolmäs, Beate Mayer, Abdelwahab H. Balola, Abdulgabar Salama   +3 more
openaire   +2 more sources

Stimulation of eryptosis by aluminium ions

Toxicology and Applied Pharmacology, 2006
Aluminium salts are utilized to impede intestinal phosphate absorption in chronic renal failure. Toxic side effects include anemia, which could result from impaired formation or accelerated clearance of circulating erythrocytes. Erythrocytes may be cleared secondary to suicidal erythrocyte death or eryptosis, which is characterized by cell shrinkage ...
Olivier M, Niemoeller, Valentin, Kiedaisch, Peter, Dreischer, Thomas, Wieder, Florian, Lang   +4 more
openaire   +2 more sources

Eryptosis in Haemochromatosis: Implications for rheology

Clinical Hemorheology and Microcirculation, 2018
BACKGROUND: Haemochromatosis is an iron-storage disease with different genetic mutations, characterized by an increased intestinal absorption of iron, resulting in a deposition of excessive amounts of iron in parenchymal cells. When the iron is released in the blood, it is left in an unliganded form, where it can participate in Haber-Weiss and Fenton ...
Jeanette N, du Plooy, Janette, Bester, Etheresia, Pretorius   +2 more
openaire   +2 more sources

Enhanced Eryptosis Following Juglone Exposure

Basic & Clinical Pharmacology & Toxicology, 2014
AbstractJuglone, a quinone isolated from Juglans mandshurica Maxim, has previously been shown to be effective against malignancy. The effect is at least partially due to stimulation of suicidal death or apoptosis of tumour cells. On the other hand, juglone has been shown to counteract apoptosis, for example, of neurons.
CALABRÒ S., ALZOUBI K., BISSINGER R., JILANI K., FAGGIO, Caterina, LANG F.   +5 more
openaire   +3 more sources

Eryptosis Is Altered in Peritoneal Dialysis Patients

Blood Purification, 2019
<b><i>Background:</i></b> Red blood cells (RBCs) undergo programmed cell death known as eryptosis. Triggers of eryptosis include increased cytosolic Ca(2+) concentration, oxidative stress, osmotic shock, energy depletion and several uremic toxins.
Virzì GM, Milan Manani S, Clementi A, Castegnaro S, Brocca A3, Riello C, de Cal M, Giuliani A, Battaglia G, Crepaldi C, Ronco C   +10 more
openaire   +3 more sources

Eryptosis, the Suicidal Death of Erythrocytes

2012
Michael Foller, Stephan Huber, Florian Lang   +2 more
exaly   +2 more sources

Triggering of eryptosis, the suicidal erythrocyte death, by phenoxodiol

Naunyn-Schmiedeberg's Archives of Pharmacology, 2019
Phenoxodiol is used for the treatment of malignancy. The substance is effective by triggering suicidal tumor cell death or apoptosis. At least in theory, phenoxodiol could similarly stimulate suicidal erythrocyte death or eryptosis. Eryptosis is characterized by cell shrinkage and breakdown of cell membrane asymmetry with phosphatidylserine ...
Fink M., Bhuyan A. A. M., Nurnberg B., Faggio C., Lang F.   +4 more
openaire   +3 more sources

Eryptosis is the programmed death of erythrocytes

Biology Bulletin Reviews, 2014
The review presents modern data on mechanisms that trigger, regulate, and inhibit programmed cell death of mature erythrocytes (eryptosis) in health and disease. Diseases characterized by elevated eryptosis, as well as a number of unsolved problems in the investigation of eryptosis, are discussed.
K. I. Bialevich, D. G. Kostsin, E. I. Slobozhanina   +2 more
openaire   +1 more source