Results 151 to 160 of about 2,020 (175)
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Eryptosis triggered by bismuth
BioMetals, 2008Bismuth is used for multiple industrial purposes and in the treatment of several gastrointestinal diseases. Untoward effects of bismuth include anemia, which could, in theory, result from suicidal erythrocyte death or eryptosis. Hallmarks of eryptosis are cell shrinkage and cell membrane scrambling with phosphatidylserine exposure at the cell surface ...
Manuel, Braun +3 more
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Eryptosis Is Altered in Peritoneal Dialysis Patients
Blood Purification, 2019<b><i>Background:</i></b> Red blood cells (RBCs) undergo programmed cell death known as eryptosis. Triggers of eryptosis include increased cytosolic Ca(2+) concentration, oxidative stress, osmotic shock, energy depletion and several uremic toxins.
Claudio Ronco +2 more
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Apoptosis and eryptosis: similarities and differences
Apoptosis, 2023Eryptosis is a regulated cell death (RCD) of mature erythrocytes initially described as a counterpart of apoptosis for enucleated cells. However, over the recent years, a growing number of studies have emphasized certain differences between both cell death modalities.
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Induction of eryptosis by cyclosporine
Naunyn-Schmiedeberg's Archives of Pharmacology, 2006Side effects of cyclosporine treatment include anemia. Most recent studies have found that anemia may be caused by triggering of suicidal erythrocyte death (eryptosis), i.e. activation of an erythrocyte scramblase and phosphatidylserine exposure at the erythrocyte surface.
Olivier M, Niemoeller +8 more
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Eryptosis: a driver of anemia in chronic kidney disease
Current Opinion in Nephrology & Hypertension, 2023Purpose of review Anemia, characterized by a reduction in red blood cell (RBC) count or hemoglobin concentration, commonly accompanies chronic kidney disease (CKD), significantly impacting patients’ quality of life. This review delves into the multifaceted nature of anemia in CKD, with a focus on novel mechanisms, particularly ...
Bissinger, R., Qadri, S.M., Artunc, F.
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Eryptosis in lead-exposed workers
Toxicology and Applied Pharmacology, 2014Eryptosis is a physiological phenomenon in which old and damaged erythrocytes are removed from circulation. Erythrocytes incubated with lead have exhibited major eryptosis. In the present work we found evidence of high levels of eryptosis in lead exposed workers possibly via oxidation. Blood samples were taken from 40 male workers exposed to lead (mean
Itzel-Citlalli, Aguilar-Dorado +5 more
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Stimulation of eryptosis by aluminium ions
Toxicology and Applied Pharmacology, 2006Aluminium salts are utilized to impede intestinal phosphate absorption in chronic renal failure. Toxic side effects include anemia, which could result from impaired formation or accelerated clearance of circulating erythrocytes. Erythrocytes may be cleared secondary to suicidal erythrocyte death or eryptosis, which is characterized by cell shrinkage ...
Olivier M, Niemoeller +4 more
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Eryptosis in Haemochromatosis: Implications for rheology
Clinical Hemorheology and Microcirculation, 2018BACKGROUND: Haemochromatosis is an iron-storage disease with different genetic mutations, characterized by an increased intestinal absorption of iron, resulting in a deposition of excessive amounts of iron in parenchymal cells. When the iron is released in the blood, it is left in an unliganded form, where it can participate in Haber-Weiss and Fenton ...
Jeanette N, du Plooy +2 more
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Eryptosis in autoimmune haemolytic anaemia
European Journal of Haematology, 2017AbstractObjectiveHaemolysis and anaemia related to autoimmune haemolytic anaemia (AIHA) of warm type (wAIHA) and of cold type (cAIHA) are believed to be solely due to antibody and/or complement‐mediated destruction and clearance of red blood cells (RBCs). There is evidence that RBCs of affected patients may also undergo eryptosis, the suicidal death of
Thilo Bartolmäs +3 more
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Enhanced Eryptosis Following Juglone Exposure
Basic & Clinical Pharmacology & Toxicology, 2014AbstractJuglone, a quinone isolated from Juglans mandshurica Maxim, has previously been shown to be effective against malignancy. The effect is at least partially due to stimulation of suicidal death or apoptosis of tumour cells. On the other hand, juglone has been shown to counteract apoptosis, for example, of neurons.
CALABRÒ S. +5 more
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