Results 1 to 10 of about 5,586,865 (266)
Cellular Physiology and Biochemistry, 2016 Background/Aims: Teriflunomide, an inhibitor of pyrimidine synthesis and thus proliferation of activated T and B lymphocytes, is successfully used for treatment of inflammatory disease. Teriflunomide has further been shown to trigger apoptosis of tumor cells and has thus been considered for the treatment of malignancy.
Jens Zierle +2 more
openaire +4 more sources
Triggering of Erythrocyte Death by Triparanol
Toxins, 2015 The cholesterol synthesis inhibitor Triparanol has been shown to trigger apoptosis in several malignancies. Similar to the apoptosis of nucleated cells, erythrocytes may enter eryptosis, the suicidal death characterized by cell shrinkage and cell ...
Arbace Officioso +3 more
doaj +1 more source
Edelfosine Induced Suicidal Death of Human Erythrocytes
Cellular Physiology and Biochemistry, 2015 Background/Aims: The anti-inflammatory, anti-autoimmune, antiparasitic, and anti-viral ether phospholipid edelfosine (1-O-octadecyl-2-O-methylglycero-3-phosphocholine) stimulates apoptosis of tumor cells and is thus considered for the treatment of ...
Marilena Briglia +4 more
doaj +1 more source
Taurolidine Sensitivity of Eryptosis, the Suicidal Erythrocyte Death
Cellular Physiology and Biochemistry, 2018 Background/Aims: The taurine derivative Taurolidine is effective against diverse bacteria and tumor growth. In the treatment of cancer, the substance is effective in part by triggering suicidal death or apoptosis of tumor cells.
Madeline Fink +3 more
doaj +1 more source
Oxaliplatin Induced Suicidal Death of Human Erythrocytes
Cellular Physiology and Biochemistry, 2015 Background/Aims: The alkylating drug oxaliplatin is widely used for chemotherapy of malignancy. Oxaliplatin is effective by inducing both, necrosis and apoptosis.
Antonella Fazio +4 more
doaj +1 more source
Simvastatin, a Novel Stimulator of Eryptosis, the Suicidal Erythrocyte Death
Cellular Physiology and Biochemistry, 2017 Background/Aims: The 3-hydroxy-3-methyl-glutaryl-Coenzyme A (HMG-CoA) reductase inhibitor simvastatin has been shown to trigger apoptosis of several cell types. The substance has thus been proposed as an additional treatment of malignancy.
Abdulla Al Mamun Al Mamun Bhuyan +4 more
doaj +1 more source
Fucoxanthin Induced Suicidal Death of Human Erythrocytes
Cellular Physiology and Biochemistry, 2015 Background/Aims: Fucoxanthin, a carotenoid isolated from brown seaweeds, induces suicidal death or apoptosis of tumor cells and is thus considered for the treatment or prevention of malignancy.
Marilena Briglia +6 more
doaj +1 more source
Stimulation of Eryptosis by Afatinib
Cellular Physiology and Biochemistry, 2018 Background/Aims: The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor afatinib is primarily utilized for the treatment of non-small cell lung carcinoma.
Abdulla Al Mamun Bhuyan, Florian Lang
doaj +1 more source
Stimulation of Suicidal Erythrocyte Death by the Antimalarial Drug Mefloquine
Cellular Physiology and Biochemistry, 2015 Background: The antimalarial drug mefloquine has previously been shown to stimulate apoptosis of nucleated cells. Similar to apoptosis, erythrocytes may enter suicidal death or eryptosis, which is characterized by cell shrinkage and phospholipid ...
Rosi Bissinger +5 more
doaj +1 more source
Enhanced Eryptosis Following Exposure to Carnosic Acid
Cellular Physiology and Biochemistry, 2015 Background/Aims: The phenolic abietane diterpene component of rosemary and sage, carnosic acid, may either induce or inhibit apoptosis of nucleated cells.
Katja Stockinger +4 more
doaj +1 more source