Results 31 to 40 of about 4,109 (159)

Stimulation of Erythrocyte Cell Membrane Scrambling by Methyldopa

Kidney and Blood Pressure Research, 2008
Methyldopa is used for treatment of hypertension in pregnancy. Side effects of methyldopa include anemia, which could result from decreased formation or accelerated death of circulating erythrocytes. Several drugs cause anemia by triggering of suicidal erythrocyte death or eryptosis, which is characterized by cell shrinkage and cell membrane scrambling,
Hasan, Mahmud, Michael, Föller, Florian, Lang   +2 more
openaire   +2 more sources

Phospholipid scrambling on the plasma membrane. [PDF]

, 2014
Regulated Cell Death Part A: Apoptotic MechanismsPhospholipids are asymmetrically distributed at plasma membrane in normal cells, and scrambled in various biological situations such as blood clotting and apoptotic cell death. Recent studies revealed that
Suzuki, Jun, Nagata, Shigekazu, Shigekazu Nagata, Jun Suzuki   +3 more
core   +1 more source

Acid Sphingomyelinase Regulates Platelet Cell Membrane Scrambling, Secretion, and Thrombus Formation [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2014
Objective— Platelet activation is essential for primary hemostasis and acute thrombotic vascular occlusions. On activation, platelets release their prothrombotic granules and expose phosphatidylserine, thus fostering thrombin generation and thrombus formation.
Münzer, Patrick, Borst, Oliver, Walker, Britta, Schmid, Evi, Feijge, Marion A. H., Cosemans, Judith M. E. M., Chatterjee, Madhumita, Schmidt, Eva-Maria, Schmidt, Sebastian, Towhid, Syeda T., Leibrock, Christina, Elvers, Margitta, Schaller, Martin, Seizer, Peter, Ferlinz, Klaus, May, Andreas E., Gulbins, Erich, Heemskerk, Johan W. M., Gawaz, Meinrad, Lang, Florian   +19 more
openaire   +3 more sources

Stimulation of Phospholipid Scrambling of the Erythrocyte Membrane by 9-Cis-Retinoic Acid

, 2017
Background/Aims: The endogenous retinoid 9-cis-retinoic acid has previously been shown to trigger apoptosis in a wide variety of cells including several tumor cells and has thus been suggested for the treatment of malignancy.
Kousi Alzoubi, Florian Lang, Majed Abed, Abdulla  Al Mamun Bhuayn   +3 more
core   +2 more sources

Enhanced Eryptosis Following Auranofin Exposure

Cellular Physiology and Biochemistry, 2015
Background/Aims: The antiinflammatory, antimicrobial and anticancer drug auranofin has previously been shown to trigger apoptosis, the suicidal death of nucleated cells. Side effects of the drug include anaemia.
Kousi Alzoubi, Jasmin Egler, Majed Abed, Florian Lang   +3 more
doaj   +1 more source

PtdSer scrambling and virus replication.

, 2022
PtdSer is shown in orange and all other phospholipid species are shown in gray. (A) Apoptotic mimicry. Enveloped viruses containing exposed PtdSer can enter cells by attaching to cell surface apoptotic clearance receptors like TIMs, TAMs, CD300 receptors,
Melinda Ann Brindley (8965325), Marissa Danielle Acciani (12197218)   +1 more
core   +1 more source

Triggering of Suicidal Erythrocyte Death by Penta-O-galloyl-β-d-glucose

Toxins, 2013
The polyphenolic 1,2,3,4,6-penta-O-galloyl-beta-d-glucose from several medicinal herbs triggers apoptosis and has, thus, been proposed for treatment of malignancy. The substance is at least partially effective through caspase activation.
Kousi Alzoubi, Sabina Honisch, Majed Abed, Florian Lang   +3 more
doaj   +1 more source

Zopolrestat Induced Suicidal Death of Human Erythrocytes

Cellular Physiology and Biochemistry, 2015
Background/Aims: The aldose reductase inhibitor zopolrestat has been shown to either decrease or increase apoptosis, the suicidal death of nucleated cells.
Ghada Bouguerra, Rosi Bissinger, Salem Abbès, Florian Lang   +3 more
doaj   +1 more source

Stimulation of Eryptosis by Combretastatin A4 Phosphate Disodium (CA4P)

Cellular Physiology and Biochemistry, 2016
Background/Aims: Combretastatin A4 phosphate disodium (CA4P) is utilized for the treatment of malignancy. The substance has previously been shown to trigger suicidal cell death or apoptosis. Similar to apoptosis of nucleated cells, erythrocytes may enter
Elena Signoretto, Rosi Bissinger, Michela Castagna, Florian Lang   +3 more
doaj   +1 more source

Triggering of Suicidal Erythrocyte Death Following Boswellic Acid Exposure

Cellular Physiology and Biochemistry, 2015
Background/Aims: The antinflammatory natural product boswellic acid is effective against cancer at least in part by inducing tumor cell apoptosis. Similar to apoptosis of nucleated cells erythrocytes may enter eryptosis, a suicidal death characterized by
Salvatrice Calabrò, Kousi Alzoubi, Caterina Faggio, Stefan Laufer, Florian Lang   +4 more
doaj   +1 more source