Results 31 to 40 of about 5,586,865 (266)
Cellular and Molecular Biology Letters, 2014 AbstractThe styryl dye FM1-43 becomes highly fluorescent upon binding to cell membranes. The breakdown of membrane phospholipid asymmetry in ionophore-stimulated T-lymphocytes further increases this fluorescence [Zweifach, 2000]. In this study, the capacity of FM1-43 to monitor membrane phospholipid scrambling was explored using flow cytometry in human
Henry Hägerstrand +2 more
exaly +3 more sources
Investigation of Phosphatidylserine-Transporting Activity of Human TMEM16C Isoforms
Membranes, 2022 Lipid scrambling is a rapid process that dissipates the asymmetrical distribution of phospholipids in the plasma membrane. It is involved in various physiological functions such as blood coagulation and apoptosis.
Hanggu Kim +2 more
doaj +1 more source
Lactose Permease Scrambles Phospholipids
Biology, 2023 Lactose permease (LacY) from Escherichia coli belongs to the major facilitator superfamily. It facilitates the co-transport of β-galactosides, including lactose, into cells by using a proton gradient towards the cell.
Lei Wang, Peter Bütikofer
doaj +1 more source
Lipopeptides in the Triggering of Erythrocyte Cell Membrane Scrambling [PDF]
Cellular Physiology and Biochemistry, 2008 Sepsis is paralleled by anemia, an effect partially resulting from eryptosis, the suicidal death of erythrocytes. Eryptosis is characterized by cell membrane scrambling with phosphatidylserine exposure at the erythrocyte surface. Pathogen-induced eryptosis may partially result from interaction of bacterial cell wall components such as lipoproteins with
Kan, Wang +7 more
openaire +2 more sources
Stimulation of Erythrocyte Cell Membrane Scrambling by Nystatin [PDF]
Basic & Clinical Pharmacology & Toxicology, 2014 AbstractThe antifungal ionophore nystatin dissipates the Na+ and K+ gradients across the cell membrane, leading to cellular gain of Na+ and cellular loss of K+. The increase of cellular Na+ concentration may result in Ca2+ accumulation in exchange for Na+.
Abaid, Malik +3 more
openaire +2 more sources
Stimulation of Erythrocyte Cell Membrane Scrambling by Amiodarone [PDF]
Cellular Physiology and Biochemistry, 2007 Side effects of amiodarone, an effective antiarrhythmic drug, include anemia, which may be caused by decreased formation or accelerated death of erythrocytes. Suicidal erythrocyte death (eryptosis) is characterized by cell shrinkage and cell membrane scrambling leading to phosphatidylserine exposure at the cell surface.
Jan P, Nicolay +4 more
openaire +2 more sources
Stimulation of Platelet Death by Vancomycin
Cellular Physiology and Biochemistry, 2013 Background/Aims: Side effects of vancomycin, a widely used antibiotic, include thrombocytopenia. The vancomycin-induced thrombocytopenia has been attributed to immune reactions.
Syeda T. Towhid +8 more
doaj +1 more source
Cell Reports, 2020 Summary: Plasma membrane damage and cell death during processes such as necroptosis and apoptosis result from cues originating intracellularly. However, death caused by pore-forming agents, like bacterial toxins or complement, is due to direct external ...
Ning Wu +16 more
doaj +1 more source
Stimulating Effect of Manumycin A on Suicidal Erythrocyte Death
Cellular Physiology and Biochemistry, 2016 Background/Aims: The streptomycete derived farnesyltransferase inhibitor Manumycin A triggers apoptosis of tumor cells and is thus considered for the treatment of malignancy.
Jasmin Egler, Jens Zierle, Florian Lang
doaj +1 more source
Stimulation of Erythrocyte Cell Membrane Scrambling by Methyldopa
Kidney and Blood Pressure Research, 2008 Methyldopa is used for treatment of hypertension in pregnancy. Side effects of methyldopa include anemia, which could result from decreased formation or accelerated death of circulating erythrocytes. Several drugs cause anemia by triggering of suicidal erythrocyte death or eryptosis, which is characterized by cell shrinkage and cell membrane scrambling,
Hasan, Mahmud +2 more
openaire +2 more sources