Results 51 to 60 of about 4,109 (159)

Edelfosine Induced Suicidal Death of Human Erythrocytes

Cellular Physiology and Biochemistry, 2015
Background/Aims: The anti-inflammatory, anti-autoimmune, antiparasitic, and anti-viral ether phospholipid edelfosine (1-O-octadecyl-2-O-methylglycero-3-phosphocholine) stimulates apoptosis of tumor cells and is thus considered for the treatment of ...
Marilena Briglia, Antonella Fazio, Elena Signoretto, Caterina Faggio, Florian Lang   +4 more
doaj   +1 more source

Functional characterisation of the lipid raft protein stomatin [PDF]

, 2005
The function of the integral membrane protein stomatin is as yet poorly understood. Stomatin is deficient from the erythrocyte membrane of patients suffering with Overhydrated Hereditary Stomatocytosis (OHSt).
Wilkinson, Dorothy Kate
core  

Taurolidine Sensitivity of Eryptosis, the Suicidal Erythrocyte Death

Cellular Physiology and Biochemistry, 2018
Background/Aims: The taurine derivative Taurolidine is effective against diverse bacteria and tumor growth. In the treatment of cancer, the substance is effective in part by triggering suicidal death or apoptosis of tumor cells.
Madeline Fink, Abdulla  Al Mamun Bhuyan, Nefeli Zacharopoulou, Florian Lang   +3 more
doaj   +1 more source

Oxaliplatin Induced Suicidal Death of Human Erythrocytes

Cellular Physiology and Biochemistry, 2015
Background/Aims: The alkylating drug oxaliplatin is widely used for chemotherapy of malignancy. Oxaliplatin is effective by inducing both, necrosis and apoptosis.
Antonella Fazio, Marilena Briglia, Caterina Faggio, Kousi Alzoubi, Florian Lang   +4 more
doaj   +1 more source

Death receptor ligation triggers membrane scrambling between Golgi and mitochondria

, 2007
Subcellular organelles such as mitochondria, endoplasmic reticulum ( ER) and the Golgi complex are involved in the progression of the cell death programme. We report here that soon after ligation of Fas (CD95/Apo1) in type II cells, elements of the Golgi
Ouasti, S., Khosravi-Far, R., P Matarrese, R. Paddon, S. Ouasti, Sorice, M., Matarrese, P., R Khosravi-Far, Tinari, A., S Ouasti, R Paddon, P. Matarrese, Paddon, R., M. Degli Esposti, Degli Esposti, M., Malorni, W., M Degli Esposti, A Tinari, R. Khosravi Far, SORICE, Maurizio, A. Tinari, M Sorice, W Malorni, W. Malorni   +23 more
core   +1 more source

Simvastatin, a Novel Stimulator of Eryptosis, the Suicidal Erythrocyte Death

Cellular Physiology and Biochemistry, 2017
Background/Aims: The 3-hydroxy-3-methyl-glutaryl-Coenzyme A (HMG-CoA) reductase inhibitor simvastatin has been shown to trigger apoptosis of several cell types. The substance has thus been proposed as an additional treatment of malignancy.
Abdulla Al Mamun Al Mamun Bhuyan, Sigrid Nüßle, Hang Cao, Shaqiu Zhang, Florian Lang   +4 more
doaj   +1 more source

Stimulation of Suicidal Erythrocyte Death by the Antimalarial Drug Mefloquine

Cellular Physiology and Biochemistry, 2015
Background: The antimalarial drug mefloquine has previously been shown to stimulate apoptosis of nucleated cells. Similar to apoptosis, erythrocytes may enter suicidal death or eryptosis, which is characterized by cell shrinkage and phospholipid ...
Rosi Bissinger, Susanne Barking, Kousi Alzoubi, Guilai Liu, Guoxing Liu, Florian Lang   +5 more
doaj   +1 more source

Calcium-dependent phospholipid scrambling by TMEM16F. [PDF]

, 2010
血小板において止血の引き金となるリン脂質の暴露に関与する因子の同定－ヒトの遺伝病（スコット症候群）の原因遺伝子の同定. 京都大学プレスリリース. 2010-11-25.In all animal cells, phospholipids are asymmetrically distributed between the outer and inner leaflets of the plasma membrane. This asymmetrical phospholipid distribution
Umeda, Masato, Suzuki, Jun, Sims, Peter J., Nagata, Shigekazu, Sims, Peter J, Shigekazu Nagata, Peter J. Sims, Masato Umeda, Jun Suzuki   +8 more
core   +1 more source

Fucoxanthin Induced Suicidal Death of Human Erythrocytes

Cellular Physiology and Biochemistry, 2015
Background/Aims: Fucoxanthin, a carotenoid isolated from brown seaweeds, induces suicidal death or apoptosis of tumor cells and is thus considered for the treatment or prevention of malignancy.
Marilena Briglia, Salvatrice Calabró, Elena Signoretto, Kousi Alzoubi, Stefan Laufer, Caterina Faggio, Florian Lang   +6 more
doaj   +1 more source

Stimulation of Eryptosis by Afatinib

Cellular Physiology and Biochemistry, 2018
Background/Aims: The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor afatinib is primarily utilized for the treatment of non-small cell lung carcinoma.
Abdulla Al Mamun Bhuyan, Florian Lang
doaj   +1 more source