Results 71 to 80 of about 4,109 (159)

Membrane Protein Mobility and Orientation Preserved in Supported Bilayers Created Directly from Cell Plasma Membrane Blebs

, 2016
Membrane protein interactions with lipids are crucial for their native biological behavior, yet traditional characterization methods are often carried out on purified protein in the absence of lipids.
Mark J. Richards (1747339), Huma Haider (1747348), Julia Kumpf (1747342), Susan Daniel (1541269), Toshimitsu Kawate (1747351), Chih-Yun Hsia (1747345), Rohit R. Singh (1747354)   +6 more
core   +2 more sources

Stimulation of Suicidal Erythrocyte Death by Rottlerin

Cellular Physiology and Biochemistry, 2016
Background/Aims: The phytochemical polyphenol rottlerin is a potent activator of diverse Ca2+ -sensitive K+ channels. Those channels play a decisive role in the execution of eryptosis, the suicidal death of erythrocytes, which is characterized by cell ...
Morena Mischitelli, Mohamed Jemaà, Mustafa Almasry, Caterina Faggio, Florian Lang   +4 more
doaj   +1 more source

Regulation of TMEM16A/ANO1 and TMEM16F/ANO6 ion currents and phospholipid scrambling by Ca²⁺and plasma membrane lipid

, 2017
TMEM16/anoctamin (ANO) proteins form Ca2+-activated ion channels or phospholipid scramblases. We found that both TMEM16A/ANO1 and TMEM16F/ANO6 produced Cl- currents when activated by intracellular Ca2+, but only TMEM16F was able to expose ...
Rainer Schreiber, Podchanart Wanitchakool, Wanitchakool, Podchanart, Kunzelmann, Karl, Benedetto, Roberta, Schreiber, Rainer, Sirianant, Lalida, Reiss, Karina, Karina Reiss, Karl Kunzelmann, Ousingsawat, Jiraporn, Jiraporn Ousingsawat, Roberta Benedetto, Lalida Sirianant   +13 more
core   +1 more source

Induction of Suicidal Erythrocyte Death by Novobiocin

Cellular Physiology and Biochemistry, 2014
Background: Novobiocin, an aminocoumarin antibiotic, interferes with heat shock protein 90 and hypoxia inducible factor dependent gene expression and thus compromises cell survival.
Adrian Lupescu, Rosi Bissinger, Tabea Herrmann, Gergely Oswald, Kashif Jilani, Florian Lang   +5 more
doaj   +1 more source

Effect of a scramblase activator upon scrambling and membrane domain formation in HEK293T cells

Faraday Discussions
A model for how loss of asymmetry due to lipid scrambling may change membrane domain formation.
Kakuda, Shinako, London, Erwin
openaire   +3 more sources

Triggering of Suicidal Erythrocyte Death by Psammaplin A

Cellular Physiology and Biochemistry, 2016
Background/Aims: Psammaplin A, a natural product isolated from marine sponges, triggers apoptosis of tumor cells and is thus considered for the treatment of malignancy. In analogy to apoptosis of nucleated tumor cells, erythrocytes may enter eryptosis, a
Abdulla Al Mamun Bhuyan, Elena Signoretto, Florian Lang   +2 more
doaj   +1 more source

Established and emerging players in phospholipid scrambling: A structural perspective

International audienceThe maintenance of a diverse and non-homogeneous lipid composition in cell membranes is crucial for a multitude of cellular processes.
Čopič, Alenka, Lenoir, Guillaume, Sebinelli, Heitor, Gobbi, Syska, Camille   +3 more
core   +1 more source

Red Blood Cell Susceptibility to Pneumolysin: Correlation with Membrane Biochemical and Physical Properties.

, 2016
This study investigated the effect of the biochemical and biophysical properties of the plasma membrane as well as membrane morphology on the susceptibility of human red blood cells to the cholesterol-dependent cytolysin pneumolysin, a key virulence ...
MA Khafaji (21845765), CE Naylor (21828041), M Bokori-Brown (21845762), CP Winlove (21843656), PG Petrov (21825521), AC Shore (16295798), F Casanova (13359666), RW Titball (21844946), MK Mughal (9899777), TJ Mitchell (7640300), KM Gooding (21830054)   +10 more
core   +2 more sources

Functional Asymmetry of The Immune Cell Plasma Membrane

, 2017
Mammalian cells maintain a distinct disparity in lipid composition between the two leaflets of the bilayer of the plasma membrane. This compositional asymmetry is most prominent for phosphatidylserine (PS), a negatively charged lipid that is found almost
Malmberg, Eric
core  

Dicoumarol activates Ca2+-permeable cation channels triggering erythrocyte cell membrane scrambling.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2012
Dicoumarol, a widely used anticoagulant, may cause anemia, which may result from enhanced erythrocyte loss due to bleeding or due to accelerated erythrocyte death. Erythrocytes may undergo suicidal death or eryptosis, characterized by cell shrinkage and phospholipid scrambling of the cell membrane. Eryptosis may be triggered by increase of cytosolic Ca(
Syed M, Qadri, Yuliya, Kucherenko, Christine, Zelenak, Kashif, Jilani, Elisabeth, Lang, Florian, Lang   +5 more
openaire   +1 more source