Results 91 to 100 of about 5,974,193 (263)

Scrambling as verum focus: German scrambling meets Romance anaphoric anteposition. [PDF]

, 2017
In this paper I demonstrate that in Mòcheno, a German dialect spoken in Northern Italy, scrambling, i.e. the movement of any constituent above sentential adverbs and below the finite verb, is permitted like in Continental Germanic languages. Unlike in
COGNOLA, FEDERICA
core   +1 more source

Caspase cleavage releases a nuclear protein fragment that stimulates phospholipid scrambling at the plasma membrane. Maruoka et al.

, 2021
Original Western blot images, Fluorescent images and Excel files relating to "Caspase cleavage releases a nuclear protein fragment that stimulates phospholipid scrambling at the plasma membrane. Maruoka et al.
Suzuki, Jun
core   +1 more source

TAB2 Causes Neuronal Damage by Aggravating Microglia‐Mediated Neuroinflammation in Parkinson's Disease

Advanced Science, EarlyView.
In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao, Zimeng Huang, Jianing Gao, Aolan Li, Huizhi Wang, Yingchuan Chen, Guanyu Zhu, Xin Zhang, Yin Jiang, Moxuan Zhang, Fangang Meng, Jianguo Zhang, Tingting Du   +12 more
wiley   +1 more source

Stimulation of Suicidal Erythrocyte Death by the CDC25 Inhibitor NSC-95397

Cellular Physiology and Biochemistry, 2016
Background/Aims: The CDC25B inhibitor NSC-95397 triggers apoptosis of tumor cells and is thus considered for the treatment of malignancy. The substance is effective in part by modification of gene expression.
Mohamed Jemaà, Morena Mischitelli, Myriam Fezai, Mustafa Almasry, Caterina Faggio, Florian Lang   +5 more
doaj   +1 more source

Loss of LCN2 Function Ameliorates Glucocorticoid‐Induced Muscle Atrophy via Remodeling the Extracellular Matrix

Advanced Science, EarlyView.
Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi, Xiaojing Hao, Yi Yan, Fengyang Li, Yaru Zhang, Zixin Li, Wenjuan Xie, Jiayin Lu, Xiaomao Luo, Yanjun Dong, Haidong Wang, Juan Wang   +11 more
wiley   +1 more source

Stimulation of Suicidal Erythrocyte Death by Phosphatase Inhibitor Calyculin A

Cellular Physiology and Biochemistry, 2016
Background/Aims: The serine/threonine protein phosphatase 1 and 2a inhibitor Calyculin A may trigger suicidal death or apoptosis of tumor cells. Similar to apoptosis of nucleated cells, erythrocytes may enter eryptosis, the suicidal erythrocyte death ...
Mustafa Almasry, Mohamed Jemaà, Morena Mischitelli, Caterina Faggio, Florian Lang   +4 more
doaj   +1 more source

Fabrication of bifunctional membrane electrode assemblies for unitised regenerative polymer electrolyte fuel cells [PDF]

, 2006
Bifunctional membrane electrode assemblies have been fabricated using a screen printing technique, which demonstrate a repeatable and stable operation to cell current and voltages.
Pettersson, J, Harrison, DJ, Ramsey, BJ
core   +1 more source

SR‐A3 Promotes USP18‐Mediated deISGylation of STING to Protect Against Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
MI/RI is a major clinical challenge with high morbidity and mortality. This study demonstrates that SR‐A3 expression is downregulated in MI/RI, and its deletion exacerbates damage via the USP18/ISG15/STING axis, revealing SR‐A3 as a potential therapeutic target.
Yufei Han, Guolin Miao, Yinqi Zhao, Zhiyong Du, Kaikai Lu, Changqi Xiao, Aiden Xian, Jiaxin Duanmu, Zihao Zhou, Jinxuan Chen, Lianxin Zhang, Chao Zhai, Yitong Xu, Zhaoling Li, Xianqin Shen, Sijing Shi, Jingxuan Chen, Si Mei, Yuan Fang, Liwen Zheng, Ling Zhang, Yuhui Wang, Wei Huang, Erdan Dong, Xunde Xian   +24 more
wiley   +1 more source

Bicarbonate stimulated phospholipid scrambling induces cholesterol redistribution and enables cholesterol depletion in the sperm plasma membrane

, 2001
Mammalian sperm cells are activated prior to fertilization by high bicarbonate levels, which facilitate lipoprotein-mediated cholesterol efflux. The role of bicarbonate and cholesterol acceptors on the cholesterol organization in the sperm plasma ...
Brouwers, JF, Flesch, Fredericus, van Golde, LM, Colenbrander, B, Nievelstein, PF, Verkleij, AJ, Gadella, BM   +6 more
core   +3 more sources

Breakdown of Phosphatidylserine Asymmetry Following Treatment of Erythrocytes with Lumefantrine

Toxins, 2014
Background: Lumefantrine, a commonly used antimalarial drug, inhibits hemozoin formation in parasites. Several other antimalarial substances counteract parasitemia by triggering suicidal death or eryptosis of infected erythrocytes.
Kousi Alzoubi, Bassel Alktifan, Gergely Oswald, Myriam Fezai, Majed Abed, Florian Lang   +5 more
doaj   +1 more source