Results 41 to 50 of about 4,109 (159)

Triggering of Suicidal Erythrocyte Death by Fascaplysin

Cellular Physiology and Biochemistry, 2016
Background/Aims: The bis-indole alkaloid Fascaplysin is effective against malignancy, an effect at least partially due to stimulation of tumor cell apoptosis. Similar to apoptosis of nucleated cells, erythrocytes could enter suicidal erythrocyte death or
Morena Mischitelli, Mohamed Jemaà, Mustafa Almasry, Caterina Faggio, Florian Lang   +4 more
doaj   +1 more source

Mitoxantrone-Induced Suicidal Erythrocyte Death

Cellular Physiology and Biochemistry, 2014
Background/Aims: Mitoxantrone, a cytotoxic drug used for the treatment of malignancy and multiple sclerosis, is at least in part effective by triggering apoptosis.
Markus Arnold, Rosi Bissinger, Florian Lang   +2 more
doaj   +1 more source

Triggering of Suicidal Erythrocyte Death by Celecoxib

Toxins, 2013
The selective cyclooxygenase-2 (COX-2) inhibitor celecoxib triggers apoptosis of tumor cells and is thus effective against malignancy. The substance is at least partially effective through mitochondrial depolarization.
Florian Lang, Kashif Jilani, Rosi Bissinger, Adrian Lupescu   +3 more
doaj   +1 more source

Piperlongumine-Induced Phosphatidylserine Translocation in the Erythrocyte Membrane

Toxins, 2014
Background: Piperlongumine, a component of Piper longum fruit, is considered as a treatment for malignancy. It is effective by inducing apoptosis. Mechanisms involved in the apoptotic action of piperlongumine include oxidative stress and activation of ...
Rosi Bissinger, Abaid Malik, Jamshed Warsi, Kashif Jilani, Florian Lang   +4 more
doaj   +1 more source

Enhanced Eryptosis Following Gramicidin Exposure

Toxins, 2015
The peptide antibiotic and ionophore gramicidin has previously been shown to trigger apoptosis of nucleated cells. In analogy to apoptosis, the suicidal death of erythrocytes or eryptosis involves cell shrinkage and cell membrane scrambling with ...
Abaid Malik, Rosi Bissinger, Guoxing Liu, Guilai Liu, Florian Lang   +4 more
doaj   +1 more source

Licochalcone A Induced Suicidal Death of Human Erythrocytes

Cellular Physiology and Biochemistry, 2015
Background: The anti-inflammatory, immunomodulatory, and antimicrobial Glycyrrhiza inflata extract component licochalcone A triggers apoptosis of tumor cells and is thus considered for the treatment of malignancy. Similar to apoptosis of nucleated cells,
Jasmin Egler, Florian Lang
doaj   +1 more source

Stimulation of Erythrocyte Death by Phloretin

Cellular Physiology and Biochemistry, 2014
Background: Phloretin, a natural component of apples, pears and strawberries, has previously been shown to stimulate apoptosis of nucleated cells. Erythrocytes may similarly enter suicidal death or eryptosis, which is characterized by cell shrinkage and ...
Rosi Bissinger, Salome Fischer, Kashif Jilani, Florian Lang   +3 more
doaj   +1 more source

Stimulation of Eryptosis by Narasin

Cellular Physiology and Biochemistry, 2015
Background/Aims: Narasin, an ionophore used for the treatment of coccidiosis, has been shown to foster apoptosis of tumor cells. In analogy to apoptosis of nucleated cells, erythrocytes may enter eryptosis, the suicidal erythrocyte death characterized by
Ghada Bouguerra, Rosi Bissinger, Salem Abbès, Florian Lang   +3 more
doaj   +1 more source

Native C3 is activated without proteolytic cleavage by transformation to C3(H2O) on phospholipid-scrambled cell membranes [PDF]

Frontiers in Immunology
Tick-over of C3 to fluid-phase C3(H 2 O) is considered the initiator of the alternative pathway by mediating random depositing of C3b on target surfaces. This slow mechanism does not explain the specificity and rapid activation of the alternative pathway in vivo
Eikrem, David, Manivel, Vivek A., Whittaker, Jacob, Hamad, Osama A., Mohlin, Camilla, Adler, Anna, Duhrkop, Claudia, Ebert, Roland, Teramura, Yuji, Nilsson Ekdahl, Kristina, Fromell, Karin, Nilsson, Bo   +11 more
openaire   +5 more sources

Triggering of Erythrocyte Death by Triparanol

Toxins, 2015
The cholesterol synthesis inhibitor Triparanol has been shown to trigger apoptosis in several malignancies. Similar to the apoptosis of nucleated cells, erythrocytes may enter eryptosis, the suicidal death characterized by cell shrinkage and cell ...
Arbace Officioso, Caterina Manna, Kousi Alzoubi, Florian Lang   +3 more
doaj   +1 more source