Lipid scrambling facilitates membrane vesiculation through decreasing membrane stiffness
Membrane blebbing plays important roles in cell migration, cytokinesis, apoptosis, as well as extracellular vesicle formation for intercellular communication.
Revathi, Adhvikaa A. +4 more
core +1 more source
IDEAL-Cell, a High Temperature Innovative Dual mEmbrAne Fuel-Cell [PDF]
IDEAL-Cell is a new concept of a high temperature fuel cell operating in the range 600-700°C. It is based on the junction between the anode part of a PCFC and the cathode part of a SOFC through a mixed H+ and O2- conducting porous ceramic membrane.
Stoynov, Z. +17 more
core +1 more source
Triggering of Suicidal Erythrocyte Death by Topotecan
Background/Aims: The topoisomerase I inhibitor topotecan is used as treatment of various malignancies. The substance is effective by triggering tumor cell apoptosis. In analogy to apoptosis of nucleated cells, erythrocytes may enter eryptosis, a suicidal
Rosi Bissinger +4 more
doaj +1 more source
The Membrane Steps of Bacterial Cell Wall Synthesis as Antibiotic Targets [PDF]
Peptidoglycan is the major component of the cell envelope of virtually all bacteria. It has structural roles and acts as a selective sieve for molecules from the outer environment. Peptidoglycan synthesis is therefore one of the most important biogenesis
Eefjan Breukink +5 more
core +1 more source
Acid Sphingomyelinase Regulates Platelet Cell Membrane Scrambling, Secretion, and Thrombus Formation [PDF]
Objective— Platelet activation is essential for primary hemostasis and acute thrombotic vascular occlusions. On activation, platelets release their prothrombotic granules and expose phosphatidylserine, thus fostering thrombin generation and thrombus formation.
Münzer, Patrick +19 more
openaire +3 more sources
Involvement of Ca2+ Activated Cl- Channel Ano6 in Platelet Activation and Apoptosis
Background/Aims: The ubiquitously expressed Ca2+ Activated Cl- Channel Ano6 participates in the stimulation of cell membrane scrambling. Defective Ano6 underlies the Scott syndrome, an inherited bleeding disorder with impaired scrambling of plasma ...
Guoxing Liu +8 more
doaj +1 more source
Phospholipid scrambling on the plasma membrane. [PDF]
Regulated Cell Death Part A: Apoptotic MechanismsPhospholipids are asymmetrically distributed at plasma membrane in normal cells, and scrambled in various biological situations such as blood clotting and apoptotic cell death. Recent studies revealed that
Suzuki, Jun +3 more
core +1 more source
Inhibition of Erythrocyte Cell Membrane Scrambling Following Energy Depletion and Hyperosmotic Shock by Alectinib [PDF]
Background/Aims: The anaplastic lymphoma kinase (ALK) inhibitor alectinib is clinically used for the treatment of ALK positive non-small-cell lung cancer. At least in part the substance is effective by triggering suicidal death or apoptosis of tumor cells. Erythrocytes are lacking mitochondria and nuclei, key organelles of apoptosis but are, similar to
Abdulla Al Mamun Bhuyan, Florian Lang
openaire +3 more sources
The FAM deubiquitylating enzyme localizes to multiple points of protein trafficking in epithelia, where it associates with E-cadherin and beta-catenin [PDF]
Copyright © 2004 by The American Society for Cell Biology.Ubiquitylation is a necessary step in the endocytosis and lysosomal trafficking of many plasma membrane proteins and can also influence protein trafficking in the biosynthetic pathway.
Murray, Rachael +11 more
core +2 more sources
Z-ring membrane anchors associate with cell wall synthases to initiate bacterial cell division [PDF]
During the transition from elongation to septation, Escherichia coli establishes a ring-like peptidoglycan growth zone at the future division site.
Peters, Katharina +9 more
core +1 more source

