Results 11 to 20 of about 5,586,865 (266)

Stimulation of Erythrocyte Cell Membrane Scrambling by Mushroom Tyrosinase [PDF]

Toxins, 2014
Background: Mushroom tyrosinase, a copper containing enzyme, modifies growth and survival of tumor cells. Mushroom tyrosinase may foster apoptosis, an effect in part due to interference with mitochondrial function.
Leonie Frauenfeld, Kousi Alzoubi, Majed Abed, Florian Lang   +3 more
doaj   +7 more sources

Triggering of Erythrocyte Cell Membrane Scrambling by Emodin [PDF]

Cellular Physiology and Biochemistry, 2016
Background/Aims: The natural anthraquinone derivative emodin (1,3,8-trihydroxy-6-methylanthraquinone) is a component of several Chinese medicinal herbal preparations utilized for more than 2000 years. The substance has been used against diverse disorders
Morena Mischitelli, Mohamed Jemaà, Mustafa Almasry, Caterina Faggio, Florian Lang   +4 more
doaj   +4 more sources

Inhibition of Erythrocyte Cell Membrane Scrambling by ASP3026 [PDF]

Cellular Physiology and Biochemistry, 2017
Background/Aims: The anaplastic lymphoma kinase (ALK) inhibitor ASP3026 is in clinical development for the treatment of ALK expressing non-small cell lung carcinoma (NSCLC). ASP3026 is in part effective by inducing apoptosis of tumor cells.
Abdulla Al Mamun Bhuyan, Rosi Bissinger, Hang Cao, Florian Lang   +3 more
doaj   +4 more sources

Stimulating Effect of Terfenadine on Erythrocyte Cell Membrane Scrambling [PDF]

Cellular Physiology and Biochemistry, 2016
Background/Aims: The antihistaminic drug Terfenadine may trigger apoptosis of tumor cells, an effect unrelated to its effect on histamine receptors.
Elena Signoretto, Michela Castagna, Abdulla Al Mamun Bhuyan, Florian Lang   +3 more
doaj   +6 more sources

Stimulation of Erythrocyte Cell Membrane Scrambling by Quinine

Cellular Physiology and Biochemistry, 2016
Background/Aims: The analkaloid drug quinine is utilized mainly for the chemoprophylaxis of malaria. The multiple side effects of quinine include hemolytic anemia and hemolytic uremic syndrome, disorders involving suicidal erythrocyte death or eryptosis,
Morena Mischitelli, Mohamed Jemaà, Mustafa Almasry, Caterina Faggio, Florian Lang   +4 more
doaj   +5 more sources

Stimulation of Erythrocyte Cell Membrane Scrambling by Adarotene

Cellular Physiology and Biochemistry, 2017
Background/Aims: The atypical retinoid E23-(40-hydroxyl-30-adamantylbiphenyl-4-yl) acrylic acid (ST1926, adarotene) is used in the treatment of malignancy. The effect of ST1926 is at least in part due to stimulation of apoptosis.
Morena Mischitelli, Mohamed Jemaàa, MyriamFezai Fezai, Mustafa Almasry, Florian Lang, Caterina Faggio   +5 more
doaj   +4 more sources

Camalexin-Induced Cell Membrane Scrambling and Cell Shrinkage in Human Erythrocytes [PDF]

Cellular Physiology and Biochemistry, 2017
Background/Aims: The thaliana phytoalexin Camalexin has been proposed for the treatment of malignancy. Camalexin counteracts tumor growth in part by stimulation of suicidal death or apoptosis of tumor cells.
Mustafa Almasry, Mohamed Jemaà, Morena Mischitelli, Florian Lang, Caterina Faggio   +4 more
doaj   +5 more sources

A cell-based scrambling assay reveals the phospholipid headgroup preference of TMEM16F on the plasma membrane. [PDF]

Proc Natl Acad Sci U S A
The asymmetric resting distribution of the three major phospholipid classes on the mammalian plasma membrane, with phosphatidylserine and phosphatidylethanolamine mostly on the inner leaflet, and phosphatidylcholine mostly on the outer leaflet, is maintained by ATP-dependent flippases and floppases that exhibit headgroup selectivity.
Teo CF, Tuomivaara ST, van Hilten N, Crottès D, Jan YN, Grabe M, Jan LY.   +6 more
europepmc   +7 more sources

Membrane disorder and phospholipid scrambling in electropermeabilized and viable cells [PDF]

Biochimica Et Biophysica Acta - Biomembranes, 2014
Membrane electropermeabilization relies on the transient permeabilization of the plasma membrane of cells submitted to electric pulses. This method is widely used in cell biology and medicine due to its efficiency to transfer molecules while limiting loss of cell viability.
Muriel Golzio, Justin Teissie, Jean-Michel Escoffre   +2 more
exaly   +4 more sources

Stimulation of Erythrocyte Cell Membrane Scrambling by Mitotane [PDF]

Cellular Physiology and Biochemistry, 2014
Background: Mitotane (1,1-dichloro-2-[o-chlorophenyl]-2-[p-chlorophenyl]ethane), a cytostatic drug used for the treatment of adrenocortical carcinomas, is effective by triggering tumor cell apoptosis. In analogy to apoptosis of nucleated cells, eryptosis
Janin Jacobi, Elisabeth Lang, Rosi Bissinger, Leonie Frauenfeld, Paola Modicano, Caterina Faggio, Majed Abed, Florian Lang   +7 more
doaj   +6 more sources