Results 11 to 20 of about 3,949 (239)
Stimulation of Erythrocyte Cell Membrane Scrambling by Mitotane [PDF]
Cellular Physiology and Biochemistry, 2014 Background: Mitotane (1,1-dichloro-2-[o-chlorophenyl]-2-[p-chlorophenyl]ethane), a cytostatic drug used for the treatment of adrenocortical carcinomas, is effective by triggering tumor cell apoptosis. In analogy to apoptosis of nucleated cells, eryptosis
Janin Jacobi +7 more
doaj +6 more sources
Stimulation of Erythrocyte Cell Membrane Scrambling by Adarotene
Cellular Physiology and Biochemistry, 2017 Background/Aims: The atypical retinoid E23-(40-hydroxyl-30-adamantylbiphenyl-4-yl) acrylic acid (ST1926, adarotene) is used in the treatment of malignancy. The effect of ST1926 is at least in part due to stimulation of apoptosis.
Morena Mischitelli +5 more
doaj +3 more sources
Stimulation of Erythrocyte Cell Membrane Scrambling by Gedunin [PDF]
Cellular Physiology and Biochemistry, 2014 Background/Aims: Gedunin, an inhibitor of heat shock protein HSP90, triggers apoptosis of tumor cells and is thus effective against malignancy. Moreover, the drug has antimalarial potency.
Adrian Lupescu +4 more
doaj +4 more sources
Inhibition of Erythrocyte Cell Membrane Scrambling by ASP3026 [PDF]
Cellular Physiology and Biochemistry, 2017 Background/Aims: The anaplastic lymphoma kinase (ALK) inhibitor ASP3026 is in clinical development for the treatment of ALK expressing non-small cell lung carcinoma (NSCLC). ASP3026 is in part effective by inducing apoptosis of tumor cells.
Abdulla Al Mamun Bhuyan +3 more
doaj +3 more sources
Stimulating Effect of Terfenadine on Erythrocyte Cell Membrane Scrambling [PDF]
Cellular Physiology and Biochemistry, 2016 Background/Aims: The antihistaminic drug Terfenadine may trigger apoptosis of tumor cells, an effect unrelated to its effect on histamine receptors.
Elena Signoretto +3 more
doaj +4 more sources
Camalexin-Induced Cell Membrane Scrambling and Cell Shrinkage in Human Erythrocytes [PDF]
Cellular Physiology and Biochemistry, 2017 Background/Aims: The thaliana phytoalexin Camalexin has been proposed for the treatment of malignancy. Camalexin counteracts tumor growth in part by stimulation of suicidal death or apoptosis of tumor cells.
Mustafa Almasry +4 more
doaj +4 more sources
Stimulation of Erythrocyte Cell Membrane Scrambling by C-Reactive Protein [PDF]
Cellular Physiology and Biochemistry, 2017 Background: Eryptosis, the suicidal erythrocyte death characterized by cell shrinkage and phosphatidylserine-translocation, is triggered by fever and inflammation.
Majed Abed +6 more
doaj +3 more sources
Stimulation of Erythrocyte Cell Membrane Scrambling by Amiodarone [PDF]
Cellular Physiology and Biochemistry, 2007 Side effects of amiodarone, an effective antiarrhythmic drug, include anemia, which may be caused by decreased formation or accelerated death of erythrocytes. Suicidal erythrocyte death (eryptosis) is characterized by cell shrinkage and cell membrane scrambling leading to phosphatidylserine exposure at the cell surface.
Jan P, Nicolay +4 more
openaire +2 more sources
Stimulation of Erythrocyte Cell Membrane Scrambling by Nystatin [PDF]
Basic & Clinical Pharmacology & Toxicology, 2014 AbstractThe antifungal ionophore nystatin dissipates the Na+ and K+ gradients across the cell membrane, leading to cellular gain of Na+ and cellular loss of K+. The increase of cellular Na+ concentration may result in Ca2+ accumulation in exchange for Na+.
Abaid, Malik +3 more
openaire +2 more sources
Lipopeptides in the Triggering of Erythrocyte Cell Membrane Scrambling [PDF]
Cellular Physiology and Biochemistry, 2008 Sepsis is paralleled by anemia, an effect partially resulting from eryptosis, the suicidal death of erythrocytes. Eryptosis is characterized by cell membrane scrambling with phosphatidylserine exposure at the erythrocyte surface. Pathogen-induced eryptosis may partially result from interaction of bacterial cell wall components such as lipoproteins with
Kan, Wang +7 more
openaire +2 more sources