Results 121 to 130 of about 1,887 (154)

Constituents of aromatic plants: II. Estragole

Fitoterapia, 2000
Estragole (ES) is a natural constituent of a number of plants (e.g. tarragon, sweet basil and sweet fennel) and their essential oils have been widely used in foodstuffs as flavouring agents. Several studies with oral, i.p. or s.c. administration to CD-1 and B6C3F1 mice have shown the carcinogenicity of ES.
M, De Vincenzi, M, Silano, F, Maialetti, B, Scazzocchio   +3 more
openaire   +2 more sources

Quantification of estragole in fennel herbal teas: Implications on the assessment of dietary exposure to estragole

Food and Chemical Toxicology, 2011
Quantification of estragole content in commercial fennel herbal teas was carried out in order to allow for a more accurate estimate of the dietary exposure to estragole. A simple and rapid analytical method, based on Stir Bar Sorptive Extraction and GC-MS, was developed for this purpose.
Antonio, Raffo, Stefano, Nicoli, Catherine, Leclercq   +2 more
openaire   +2 more sources

Modeling the hydroxylation of estragole via human liver cytochrome P450

Journal of Molecular Modeling, 2021
Natural compounds derived from plants are generally regarded safe and devoid of adverse effects. However, there are individual ingredients that possess toxic, genotoxic, and carcinogenic activities. These compounds when exposed at specific level become hazardous to health. Estragole (1-allyl-4-methoxybenzene) is a common component of spice plants.
Rolly, Yadav, Nidhi, Awasthi, Anamika, Shukla, Devesh, Kumar   +3 more
openaire   +2 more sources

The millimetre-wave spectrum of estragole

Chemical Physics Letters, 2013
Abstract The rotational spectrum of estragole has been investigated using a free-jet millimetre-wave spectrometer. Computational chemistry calculations at different levels of theory predict three possible conformers of estragole that are within 200 cm − 1 of each other.
Peter D. Godfrey, Don McNaughton, Corey J. Evans   +2 more
openaire   +1 more source

Immunochemical Identification of Hepatic Protein Adducts Derived from Estragole

Chemical Research in Toxicology, 1998
Hepatic protein adducts derived from the allylbenzene food flavor estragole, which is hepatocarcinogenic when given to rodents at high doses, have been identified using immunochemical approaches. Male Fischer 344 rats were given estragole orally and hepatic protein adducts were detected by immunoblotting, using antisera raised by immunizing rabbits ...
H, Wakazono, I, Gardner, E, Eliasson, M W, Coughtrie, J G, Kenna, J, Caldwell   +5 more
openaire   +2 more sources

Isomerization of Estragole to Anethole

Synthetic Communications, 1980
Abstract Anethole (trans-isomer, I) is an industrially significant organic which has found use predominantly as a flavor and fragrance (licorice) chemical. I is a component of many essential oils, e.g., fennel oils, from which it is isolated for application.
openaire   +1 more source

Estragole, a potential attractant of the winged melon aphid Aphis gossypii

Pest Management Science, 2023
AbstractBACKGROUNDAphids are sap‐sucking insect pests of economic importance. They exhibit polyphenism, producing two kinds of morphotypes; winged (alate) and wingless (aptera) morphs. While wingless morphs can be controlled by insecticides, winged morphs are a challenge for targeted control measures as they can fly.
Subhash Shivaramu, Saravan Kumar Parepally, Varun Yennurukadirenahalli Byregowda, Kamala Jayanthi Pagadala Damodaram, Anuj Bhatnagar, Kailash Chandra Naga, Sanjeev Sharma, Manoj Kumar, Vivek Kempraj   +8 more
openaire   +2 more sources

Study of the Metabolism of Estragole in Humans Consuming Fennel Tea

Chemical Research in Toxicology, 2009
The metabolism of the potent carcinogen estragole was investigated in humans after consumption of fennel tea by analyses of its metabolites in blood plasma and urine. Stable isotope dilution assays based on LC-MS/MS detection revealed that 1'-hydroxylation of estragole happened very fast as the concentration of conjugated 1'-hydroxyestragole in urine ...
Annette, Zeller, Kathie, Horst, Michael, Rychlik   +2 more
openaire   +2 more sources

Estragole Analogues as Attractants for Corn Rootworms (Coleoptera: Chrysomelidae)

Journal of Economic Entomology, 1989
Adults of two closely related corn rootworms, Diabrotiea barberi Smith and Lawrence and D. virgifera virgifera LeConte, are strongly attracted to two naturally occurring phenylpropanoids, eugenol and estragole respectively. The close chemical relationship of these two kairomones suggested that structure-activity studies of estragole analogues as ...
Robert L. Metcalf, Richard L. Lampman
openaire   +1 more source

In vivo genotoxicity of estragole in maleF344 rats

Environmental and Molecular Mutagenesis, 2014
Estragole, a naturally occurring constituent of various herbs and spices, is a rodent liver carcinogen which requires bio‐activation. To further understand the mechanisms underlying its carcinogenicity, genotoxicity was assessed in F344 rats using the comet, micronucleus (MN), and DNA adduct assays together with histopathological analysis.
Wei, Ding, Dan D, Levy, Michelle E, Bishop, Mason G, Pearce, Kelly J, Davis, Alan M, Jeffrey, Jian-Dong, Duan, Gary M, Williams, Gene A, White, Lascelles E, Lyn-Cook, Mugimane G, Manjanatha   +10 more
openaire   +2 more sources