Results 11 to 20 of about 2,725 (200)

Estragole blocks neuronal excitability by direct inhibition of Na+ channels [PDF]

Brazilian Journal of Medical and Biological Research, 2013
Estragole is a volatile terpenoid, which occurs naturally as a constituent of the essential oils of many plants. It has several pharmacological and biological activities.
K.S. Silva-Alves, F.W. Ferreira-da-Silva, D. Peixoto-Neves, K.V. Viana-Cardoso, L. Moreira-Junior, M.B. Oquendo, K. Oliveira-Abreu, A.A.C. Albuquerque, A.N. Coelho-de-Souza, J.H. Leal-Cardoso   +9 more
doaj   +5 more sources

Effects of estragole on the compound action potential of the rat sciatic nerve [PDF]

Brazilian Journal of Medical and Biological Research, 2004
Estragole, a relatively nontoxic terpenoid ether, is an important constituent of many essential oils with widespread applications in folk medicine and aromatherapy and known to have potent local anesthetic activity.
J.H. Leal-Cardoso, B.G. Matos-Brito, J.E.G. Lopes-Junior, K.V. Viana-Cardoso, A.B. Sampaio-Freitas, R.O. Brasil, A.N. Coelho-de-Souza, A.A.C. Albuquerque   +7 more
doaj   +5 more sources

Human Cytochrome P450 Enzyme Specificity for the Bioactivation of Estragole and Related Alkenylbenzenes

Chemical Research in Toxicology, 2007
Human cytochrome P450 enzymes involved in the bioactivation of estragole to its proximate carcinogen 1'-hydroxyestragole were identified and compared to the enzymes of importance for 1'-hydroxylation of the related alkenylbenzenes methyleugenol and safrole. Incubations with Supersomes revealed that all enzymes tested, except P450 2C8, are intrinsically
Jeurissen, S.M.F., Punt, A., Boersma, M.G., Bogaards, J.J.P., Fiamegos, Y.C., Schilter, B., van Bladeren, P.J., Cnubben, N.H.P., Rietjens, I.M.C.M.   +8 more
openaire   +4 more sources

Effect of Organic and Bio-Fertilization on Fruit Yield, Bioactive Constituents, and Estragole Content in Fennel Fruits

Agronomy, 2023
Fennel fruits (Foeniculum vulgare Mill.) represent one of the plant-based natural spices. This study aims to improve the fruit yield and essential oil (EO) quality by reducing the undesirable component, estragole, under different fertilizer treatments ...
Hossam S. El-Beltagi, Ramy S. Nada, Emad Mady, Ashmawi E. Ashmawi, Ebtesam Abdullah Gashash, Ahmed A. Elateeq, Ahmad A. Suliman, Nadi Awad Al-Harbi, Salem Mesfir Al-Qahtani, Mostafa M. Zarad, Timothy O. Randhir   +10 more
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Field effects of oxygenated monoterpenes and estragole combined with pheromone on attraction of Ips typographus and its natural enemies [PDF]

Frontiers in Forests and Global Change, 2023
IntroductionCentral European Norway spruce monocultures face Ips typographus outbreaks due to decreasing resistance. These beetles use volatile compounds to communicate and select suitable host trees.
Antonioni Acacio Campos Moliterno, Rastislav Jakuš, Rastislav Jakuš, Roman Modlinger, C. Rikard Unelius, Fredrik Schlyter, Fredrik Schlyter, Anna Jirošová   +7 more
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Bio‐Based Epoxy Resins from Estragole: Achieving High Glass Transition Temperatures Comparable to DGEBA and Simultaneously Low Viscosities

Macromolecular Materials and Engineering
This study covers the synthesis and characterization of two new bio‐based epoxy monomers, diglycidyl‐4‐allylphenol (DG‐4A) and triglycidyl‐diallylphenol (TG‐DA). Both are derived from estragole, a naturally occurring allylbenzene and a major component of
Florian Bauer, Elisabeth Schamel, Herbert Schlachter, Gerd Wehnert, Dominik Söthje   +4 more
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Basil essential oil: Estragole content and chemical profiles

Acta Alimentaria
AbstractBasil (sweet basil, Ocimum basilicum L.) is an aromatic plant known for its culinary and traditional medicinal uses.The content of estragole (methyl chavicol), a compound associated with a potential risk to human health, was determined in the essential oils of 12 samples of basil herb by gas chromatography with flame ionisation and mass ...
J. Arsenijević, A. Jovanović, N. Kovačević, M. Drobac   +3 more
openaire   +4 more sources

A physiologically based biodynamic (PBBD) model for estragole DNA binding in rat liver based on in vitro kinetic data and estragole DNA adduct formation in primary hepatocytes

Toxicology and Applied Pharmacology, 2010
Estragole has been shown to be hepatocarcinogenic in rodent species at high-dose levels. Translation of these results into the likelihood of formation of DNA adducts, mutation, and ultimately cancer upon more realistic low-dose exposures remains a challenge.
Paini, A., Punt, A., Viton, F., Scholz, G., Delatour, T., Marin-Kuan, M., Schilter, B., van Bladeren, P.J., Rietjens, I.   +8 more
openaire   +3 more sources

A physiologically based biokinetic (PBBK) model for estragole bioactivation and detoxification in rat

Toxicology and Applied Pharmacology, 2008
The present study defines a physiologically based biokinetic (PBBK) model for the alkenylbenzene estragole in rat based on in vitro metabolic parameters determined using relevant tissue fractions, in silico derived partition coefficients, and physiological parameters derived from the literature. The model consists of eight compartments including liver,
Punt, A., Freidig, A.P., Delatour, T., Scholz, G., Boersma, M.G., Schilter, B., Bladeren, P.J. van, Rietjens, I.M.C.M.   +7 more
openaire   +5 more sources

Distribution of Trans-Anethole and Estragole in Fennel (Foeniculum vulgare Mill) of Callus Induced from Different Seedling Parts and Fruits

Notulae Scientia Biologicae, 2011
In the present study, seeds from local cultivar of fennel were germinated on Murashige and Skoog medium (MS) without plant growth regulators. Different types of explants from the growing seedling such as cotyledonal leaves, hypocotyls, epicotyls and ...
Abd El-Moneim Mohamed Radwan AFIFY, Hossam Saad EL-BELTAGI, Anwer Abd El-Aziz HAMMAMA, Mahassen Mohamed SIDKY, Omneya Farouk Ahmed MOSTAFA   +4 more
doaj   +3 more sources