Results 121 to 130 of about 2,243,537 (271)
Advanced Science, EarlyView.The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng +8 more
wiley +1 more source
International Journal of Endocrinology, 2013 Estradiol (E2) promotes metastatic propensity. However, the detailed mechanism remains largely unknown. E-cadherin, vimentin, and MMP-9 play a dominant role in the metastatic process.
Wenwu Dong +7 more
doaj +1 more source
Systems biology of breast cancer [PDF]
, 2013 Breast cancer, with an alarming incidence rate throughout the globe, has attracted significant investigations to identify disease specific biomarkers.
Dhondalay, GKR
core
Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy
Advanced Science, EarlyView.Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao +2 more
wiley +1 more source
Journal of Agriculture and Food ResearchEnterolactone, a mammalian enterolignan, is a gut microbe-generated plant-lignan derivative. Although observational data are controversial, meta-analyses have affirmed that plant lignan-rich diets, or high serum enterolactone, reduce breast cancer risk ...
Juana Hatwik +2 more
doaj +1 more source
Advanced Science, EarlyView.A sono‐responsive chemo‐immune checkpoint nanoinhibitor (Sono‐TT8) co‐delivering TPZ chemotherapy and siXkr8 simultaneously kills tumor cells and blocks PS externalization, reversing chemotherapy‐induced immunosuppression and enhancing antitumor immunity. ABSTRACT Breast cancer features an immunosuppressive tumor microenvironment following chemotherapy
Yunfan Liu +13 more
wiley +1 more source
Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy
Advanced Science, EarlyView.A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao +10 more
wiley +1 more source
Acta Medica Iranica, 2016 Alzheimer’s disease (AD) is a disorder with multiple pathophysiological causes, destructive outcomes, and no available definitive cure. Pelargonidin (Pel), an anthocyanin derivative, is an estrogen receptor agonist with little estrogen side effects. This
Hamid Sohanaki +3 more
doaj
Progress of estrogen receptor and spliceosome in endometrial carcinoma
Frontiers in EndocrinologyEndometrial cancer (EC) is one of the most common gynecological cancers in developed countries. Like EC, most female reproductive tract malignancies are thought to be hormonally driven, with estrogen signaling acting as an oncogenic signal.
Ziqi Hong +4 more
doaj +1 more source
Advanced Science, EarlyView.This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou +8 more
wiley +1 more source