Results 181 to 190 of about 82,886 (305)

Nonlinear association of triglyceride‐glucose body mass index with all‐cause mortality in postmenopausal women, a retrospective cohort study: Evidence from the 2001 to 2014 National Health and nutrition examination survey

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background The triglyceride‐glucose body mass index (TyG‐BMI) is a novel indicator combining an insulin resistance proxy (TyG index) with adiposity. It remains unclear how TyG‐BMI relates to long‐term mortality risk in postmenopausal women, a group prone to metabolic changes after menopause.
Xiliang Wang, Kaiyue Wang, Chang Tan, Yuexin Yu   +3 more
wiley   +1 more source

The association between estrogen receptor alpha gene rs746432 polymorphism and the risk of breast cancer [PDF]

, 2018
Bei Wang, Fenlai Yuan
openalex   +1 more source

Astragaloside IV inhibits vascular calcification through estrogen receptor alpha. [PDF]

Geriatr Gerontol Int
Nanao-Hamai M, Son BK, Ogawa S, Akishita M.   +3 more
europepmc   +1 more source

Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss

iMetaMed, EarlyView.
As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu, Cenlan Bu, Qinzheng Xu, Xi Cheng, Junrong Zhang, Jinling Chen, Yun‐Zhao Xu   +6 more
wiley   +1 more source

CCAAT-displacement protein/cut homeobox transcription factor (CUX1) represses estrogen receptor-alpha (ER-α) in triple-negative breast cancer cells and can be antagonized by muscadine grape skin extract (MSKE)

, 2019
Liza J. Burton, Ohuod Hawsawi, Janae D. Sweeney, Nathan J. Bowen, Tamaro Hudson, Valerie Odero-Marah   +5 more
openalex   +2 more sources

Move beyond free radical theory of aging

iMetaOmics, EarlyView.
Free radicals play a dual, dose‐dependent role in aging. Low levels activate the key sensor adenosine 5'‐monophosphate‐activated protein kinase (AMPK), promoting cell survival mechanisms like autophagy and enhancing mitochondrial health. High levels, however, push AMPK to initiate cell death pathways, such as apoptosis. This positions AMPK as a central
Xiaofeng Dai, Meilan Hu, Ruohan Lyu
wiley   +1 more source

Altered thermal preference by preoptic estrogen receptor alpha neurons in postpartum females. [PDF]

Mol Metab
Zhang N, Yu M, Zhao Q, Feng B, Deng Y, Bean JC, Liu Q, Eappen BP, He Y, Conde KM, Liu H, Yang Y, Tu L, Wang M, Li Y, Yin N, Liu H, Han J, Threat DA, Xu N, Smiley T, Xu P, Chen L, Zeng T, He Y, Wang C.   +25 more
europepmc   +1 more source

Metastasis‐associated protein 1 participates in regulating luminal acidification of the epididymis via repressing estrogen receptor alpha transcription [PDF]

Pang Cheng, Jinhua Wei, Bo Liu, Ya Zhao, Binfang Ma, Xiao Feng, Ming‐Xiang Xiong, Jie Zhao, Changhong Shi, Zhen Li   +9 more
openalex   +1 more source

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

Interdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang, Shiwen Deng, Fangfang Jin, Jiayao Qu, Xiang Fan, Peng Chen, Xinrong Fan   +6 more
wiley   +1 more source

Sex Differences in Colonic Inflammation are Driven by Epithelial-Specific Expression of Estrogen Receptor Alpha. [PDF]

Gastro Hep Adv
Pereda GA, Kocinski AD, Broncano AV, McNeer SK, Raymond ML, Ziats NP, Breau KA, Burclaff J, Magness ST, Goodman WA.   +9 more
europepmc   +1 more source