Recurrent Cutaneous Tuberculosis in an Immunocompetent 7-Year-Old Male [PDF]
Cutaneous tuberculosis (TB) makes up a small proportion of the 10.4 million cases around the world. Although it is more commonly found in the developing world, cutaneous TB is rarely reported in the developed countries.
Austin, Dena +4 more
core +2 more sources
Role of ethambutol and rifampicin in the treatment of Mycobacterium avium complex pulmonary disease
Background A three-drug regimen (macrolide, ethambutol, and rifampicin) is recommended for the treatment of Mycobacterium avium complex pulmonary disease (MAC-PD).
Hyung-Jun Kim +6 more
doaj +1 more source
Ethambutol induced toxic optic neuropathy in HIV positive patients [PDF]
AIM:To determine whether HIV and the use of antiretroviral therapy is a risk factor for the development of ethambutol toxic optic neuropathy. To describe the clinical course of ethambutol toxic optic neuropathy in patients with HIV and to identify ...
Hamzah Mustak, Graeme Rogers, Colin Cook
doaj +1 more source
New and Improved Diagnostics for Detection of Drug-Resistant Pulmonary Tuberculosis. [PDF]
PURPOSE OF REVIEW: Tuberculosis (TB) remains a global emergency and continues to kill 1.7 million people globally each year. Drug-resistant TB is now well established throughout the world and most TB patients are not being screened for drug resistance ...
Affolabi +41 more
core +1 more source
Medication Complications in Extracorporeal Membrane Oxygenation. [PDF]
The need for extracorporeal membrane oxygenation (ECMO) therapy is a marker of disease severity for which multiple medications are required. The therapy causes physiologic changes that impact drug pharmacokinetics.
Aebi +99 more
core +2 more sources
Risk of acquired drug resistance during short-course directly observed treatment of tuberculosis in an area with high levels of drug resistance. [PDF]
BACKGROUND: Data on the performance of standardized short-course directly observed treatment (DOTS) of tuberculosis (TB) in areas with high levels of drug resistance and on the potential impact of DOTS on amplification of resistance are limited ...
Cox +33 more
core +2 more sources
Treatment outcomes for children with multidrug-resistant tuberculosis: a systematic review and meta-analysis [PDF]
BACKGROUND: Paediatric multidrug-resistant (MDR) tuberculosis is a public health challenge of growing concern, accounting for an estimated 15% of all global cases of MDR tuberculosis. Clinical management is especially challenging, and recommendations are
Abubakar +42 more
core +2 more sources
Based on real-time allele-specific polymerase chain reaction, the ranges of potential mutations in codons of 306 and 405 of the embBgene in Mycobacterium tuberculosis associated with resistance to ethambutol were investigated.
Yu. S. Аlyapkinа +5 more
doaj +1 more source
Four decades of transmission of a multidrug-resistant Mycobacterium tuberculosis outbreak strain [PDF]
The rise of drug-resistant strains is a major challenge to containing the tuberculosis (TB) pandemic. Yet, little is known about the extent of resistance in early years of chemotherapy and when transmission of resistant strains on a larger scale became a
Balloux, Francois +6 more
core +4 more sources
A Female Patient with Down Syndrome and Low-Penetrance Leber's Hereditary Optic Neuropathy. [PDF]
We present the case of a 19-year-old female with a history of Down syndrome (DS) who was referred to our neuro-ophthalmology clinic for evaluation of Leber's hereditary optic neuropathy (LHON).
Frousiakis, Starleen E +3 more
core +3 more sources

