Results 51 to 60 of about 39,846 (186)

Fluoroquinolones and isoniazid-resistant tuberculosis: implications for the 2018 WHO guidance. [PDF]

, 2019
INTRODUCTION: 2018 World Health Organization (WHO) guidelines for the treatment of isoniazid (H)-resistant (Hr) tuberculosis recommend a four-drug regimen: rifampicin (R), ethambutol (E), pyrazinamide (Z) and levofloxacin (Lfx), with or without H ([H]RZE-
Abbara, A, Abubakar, I, Alexander, E, Baker, LV, Barrett, JC, Booth, H, Bothamley, GH, Burgess, H, Cosgrove, C, Creer, DD, Davidson, JA, Dunleavy, A, Francis, M, Grp, LINH-RTBS, Gupta, U, Hamid, S, Harris, RJ, Haselden, BM, Holden, E, Kahr, V, Kon, OM, Kunst, H, Lalor, MK, Lipman, MC, Loebinger, MR, Loutet, MG, Lozewicz, S, Lynn, W, McHugh, TD, Milburn, HJ, Mohiyuddin, T, Palchaudhuri, P, Perrin, FM, Phillips, PPJ, Rahman, A, Schmok, E, Soobratty, MR, Stagg, HR, Taylor, L   +38 more
core   +4 more sources

Drug-Resistant Tuberculosis--Current Dilemmas, Unanswered Questions, Challenges and Priority Needs [PDF]

, 2012
Tuberculosis was declared a global emergency by the World Health Organization (WHO) in 1993. Following the declaration and the promotion in 1995 of directly observed treatment short course (DOTS), a cost-effective strategy to contain the tuberculosis ...
Abubakar, Ibrahim, Atun, Rifat, Chakaya, Jeremiah, Cox, Helen, Ditiu, Lucica, Ford, Nathan, Grobusch, Martin, Hoelscher, Michael, Lawn, Stephen D., Maeurer, Markus, Marais, Ben, Mchugh, Timothy D., McNerney, Ruth, Memish, Ziad, Migliori, Giovanni-Battista, Mwaba, Peter, O'Grady, Justin, Pletschette, Michel, Ramsay, Andrew, Raviglione, Mario, Schito, Marco, Squire, S. Bertel, Swaminathan, Soumya, Zumla, Alimuddin   +23 more
core   +1 more source

Development of Co-Amorphous Systems for Inhalation Therapy—Part 2: In Silico Guided Co-Amorphous Rifampicin–Moxifloxacin and –Ethambutol Formulations

Pharmaceutics
Background/Objectives: Tuberculosis (TB) remains a global health challenge due to long treatment durations, poor adherence, and growing drug resistance. Inhalable co-amorphous systems (COAMS) offer a promising strategy for targeted pulmonary delivery of ...
Eleonore Fröhlich, Noon Sharafeldin, Valerie Reinisch, Nila Mohsenzada, Stefan Mitsche, Hartmuth Schröttner, Sarah Zellnitz-Neugebauer   +6 more
doaj   +1 more source

Epicutaneous and Drug Provocation Testing in Severe Cutaneous Adverse Reactions: A 20‐Year Single‐Centre Experience

Contact Dermatitis, EarlyView.
This study provides reassuring evidence in favour of early skin testing in patients with SCARs, argues against the necessity of a 6‐month delay, and underscores the pivotal role of oral provocation tests in the safe reintroduction of essential therapies. ABSTRACT Background Identifying and discontinuing the offending drug(s) in severe cutaneous adverse
Zohra Chadli, Khadija Mansour, Ghada Jaouahdou, Manel Ben Belgacem, Yosra Soua, Nadia Ben Fredj, Jameleddine Zili, Haifa Ben Romdhane, Karim Aouam   +8 more
wiley   +1 more source

Ethambutol-induced optic neuropathy

Biomedical Papers, 2023
Purpose. A case report of a 40-year-old patient with tuberculosis treated with ethambutol is described. Within six months of starting treatment, there was a painless sudden decline in visual function.
Martin Kyncl, Martin Fus, Jan Lestak
doaj   +1 more source

Cutaneous non‐tuberculous mycobacterial infections: A retrospective study of 94 cases from Germany

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Cutaneous non‐tuberculous mycobacterial infections (NTM) remain a diagnostic and therapeutic challenge. The aim of this study was to characterize cutaneous NTM infections in Germany over a 24‐year‐period. Patients and Methods 73 patients with cutaneous NTM infections diagnosed at 17 different German University Hospitals from 2000 ...
Luisa Bopp, Nicolai Deresz, Henning Klapproth, Isabelle Suárez, Jonathan Jantsch, Mario Fabri, Esther von Stebut   +6 more
wiley   +1 more source

Secondary Tuberculosis of Tonsil case report and literature review [PDF]

, 2012
A case report of secondary tuberculosis of tonsil is being discussed along with review of published literature. This report attempts to draw attention to the fact that Tuberculosis is resurgentdespite excellent chemotherapeutic drugs available.
Ramamoorthy, Geetha, Thiagarajan, Balasubramanian, Ulaganathan, Venkatesan   +2 more
core   +1 more source

Role of therapeutic drug monitoring in pulmonary infections : use and potential for expanded use of dried blood spot samples [PDF]

, 2015
Respiratory tract infections are among the most common infections in men. We reviewed literature to document their pharmacological treatments, and the extent to which therapeutic drug monitoring (TDM) is needed during treatment.
Akkerman, Onno W, Alffenaar, Jan-Willem C, Bolhuis, Mathieu S, Hofman, Susan, Koster, Remco A, Stove, Christophe, van Assen, Sander   +6 more
core   +2 more sources

Persistent Hyperglycaemia and Transient Dysglycaemia in Tuberculosis: Evaluating the Bidirectional Interaction With Type‐2 Diabetes Mellitus and Clinical Outcomes

Tropical Medicine &International Health, EarlyView.
ABSTRACT Introduction Poor glycaemic control, indicated by a haemoglobin A1c (HbA1c) level of 7% or higher, increases the risk of active tuberculosis (TB) in patients with diabetes, while active TB can worsen glucose tolerance and insulin resistance, contributing to type‐2 diabetes mellitus (DM) progression.
Augustine Asare Boadu, Prince Asare, Michelle Yeboah‐Manu, Stephen Osei‐Wusu, Emelia Danso Konadu, Adwoa Asante‐Poku, Yayra Klinogo, Abraham Adjei, Desmond Omane Acheampong, Jane S. Afriyie‐Mensah, Dorothy Yeboah‐Manu, Yacoba Atiase   +11 more
wiley   +1 more source

Clinical Manifestations and Outcomes of Tubercular Uveitis in Taiwan—A Ten-Year Multicenter Retrospective Study

Medicina, 2022
Background andObjectives: This 10-year multicenter retrospective study reviewed the clinical manifestations, diagnostic tests, and treatment modalities of tubercular uveitis (TBU), including direct infection and indirect immune-mediated hypersensitivity ...
Chun-Ju Lin, Ning-Yi Hsia, De-Kuang Hwang, Yih-Shiou Hwang, Yo-Chen Chang, Yueh-Chang Lee, Yung-Ray Hsu, Po-Ting Yeh, Chang-Ping Lin, Hsi-Fu Chen, Wei-Chun Jan, Wei-Yu Chiang, Ming-Ling Tsai   +12 more
doaj   +1 more source