Results 171 to 180 of about 44,236 (236)

AMPA Receptor Within the Prelimbic Cortex Regulates Propofol-Induced Locomotor Sensitization. [PDF]

open access: yesAddict Biol
Pan C   +9 more
europepmc   +1 more source

Noncompetitive excitatory amino acid receptor antagonists

Trends in Pharmacological Sciences, 1990
In the first article in this series, Watkins, Krogsgaard-Larsen and Honoré outlined the structure-activity requirements at the receptor sites for excitatory amino acids in the mammalian CNS. The postsynaptic depolarizing actions of glutamate are thought to be mediated by NMDA, AMPA and kainate receptors. Here David Lodge and Kenneth M.
D, Lodge, K M, Johnson
openaire   +2 more sources

Overview: Excitatory Amino Acid Antagonists

Current Opinion on Therapeutic Patents, 1992
(1992). Overview: Excitatory Amino Acid Antagonists. Current Opinion on Therapeutic Patents: Vol. 2, No. 8, pp. 1201-1221.
Michael Rowley, Paul D Leeson
openaire   +1 more source

6 Excitatory amino acid antagonists

Baillière's Clinical Anaesthesiology, 1996
Summary l -glutamate is a major excitatory neurotransmitter in the mammalian central nervous system. It acts through ion channel receptors of the AMPA and NMDA subtypes, and selective antagonists acting on these receptors are available. Both in vitro and in vivo animal studies have demonstrated that glutamate antagonists, particularly those acting ...
Leslie L. Iversen, Kennedy R. Lees
openaire   +1 more source

Anticonvulsant Action of Excitatory Amino Acid Antagonists

Science, 1982
Compounds that antagonize neuronal excitation induced by dicarboxylic amino acids were tested in two animal models of epilepsy, namely sound-induced seizures in DBA/2 mice and threshold pentylenetetrazol seizures in Swiss mice. Sound-induced seizures could be prevented by intracerebroventricular injection of compounds that block excitation due to N ...
Croucher, M J   +2 more
openaire   +2 more sources

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