Results 201 to 210 of about 44,108 (332)

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source

Cerebellar Abnormalities: A Component of Autism Pathophysiology. [PDF]

Medicina (Kaunas)
Jagadapillai R, Tuncali I, Nagarajan N, Barnes G, Gozal E.   +4 more
europepmc   +1 more source

4-Aminopyridine reveals presynaptic GABA actions in rat sympathetic ganglia [PDF]

, 1981
Galvan, Martin, Grafe, Peter, Ten Bruggencate, Gerrit   +2 more
core  

A comparison of excitatory amino acid antagonists acting at primary afferent C fibres and motoneurones of the isolated spinal cord of the rat [PDF]

, 1987
Richard H. Evans, Simon J. Evans, Peter C.K. Pook, David C. Sunter   +3 more
openalex   +1 more source

N4‐acetylcytidine in LncRNA Gm26917 Promotes Translation in Female Germline Stem Cells by Recruiting Ribosomal Protein mRNA via EEF1A1

Advanced Science, EarlyView.
This work establishes that ac4C modification on lncRNA Gm26917 governs its spatial interactions with Rpl10 mRNA, and RBP EEF1A1 mediates the interaction between Gm26917 and Rpl10. It elucidates a novel ac4C‐Gm26917‐EEF1A1‐Rpl10 axis in FGSC maintenance both in vitro and in vivo, and provides a potential molecular target for modulating germ cell ...
Xinyue Li, Xiaopeng Hu, Ji Wu
wiley   +1 more source

Robust serotonin activation of the kisspeptin GnRH pulse generator in male and female mice.

Endocrinology
Morris PG, Liu X, Birt E, Vas S, Ruiz Cruz M, Schafer D, McQuillan HJ, Herbison AE.   +7 more
europepmc   +1 more source

Involvement of the hypothalamus-raphe magnus-spinal defecation center axis in stress-induced defecation in rats. [PDF]

Commun Biol
Yuki N, Sawamura T, Mori A, Yamaguchi H, Horii Y, Shiina T, Shimizu Y.   +6 more
europepmc   +1 more source

Interaction of excitatory amino acid antagonists and calcium channel inhibitors in the electroconvulsive test in mice

, 1995
Maciej Gąsior, Kinga K. Borowicz, Z Kleinrok, Stanisław J. Czuczwar   +3 more
openalex   +1 more source

Excitatory amino acid receptor antagonists decrease hypoxia induced increase in extracellular dopamine in striatum of newborn piglets

, 1998
Meng‐Fai Kuo, Dekun Song, Stephanie J. Murphy, María Delivoria Papadopoulos, David F. Wilson, Anna Pastuszko   +5 more
openalex   +1 more source

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

Advanced Science, EarlyView.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang, Siqi Guo, Jing Li, Qianqian Huang, Jing Ning, Binbin Xia, Xun Lv, Xiang Liu, Zeyu Gao, Jine Li, Longchao Liu, Moshi Song, Jun Wang   +12 more
wiley   +1 more source