Results 141 to 150 of about 83,508 (337)

Neurotransmitter signaling in white matter [PDF]

, 2014
Butt, Arthur M., Fern, Robert F., Matute, Carlos   +2 more
core   +1 more source

Daily intermittent fasting is an effective multiscale treatment in preclinical models of absence epilepsy

Epilepsia, EarlyView.
Abstract Objective Absence epilepsy is characterized by brief but frequent seizures with loss of consciousness. Existing treatments, which come with heavy side effects, are only partially effective and do not address the associated comorbidities, including cognitive and social deficits.
Coline Rulhe, Steeve Thirard, Juri Aparicio Arias, Leila Makrini, Florence Fauvelle, Emmanuelle Beyne, Alexandra Dauvé, Tristan Bouschet, Emmanuel Valjent, Federica Bertaso   +9 more
wiley   +1 more source

Functional reduction of SK3-mediated currents precedes AMPA-receptor-mediated excitotoxicity in dopaminergic neurons

, 2010
Bruno A. Benítez, Helen M. Belálcazar, Agustín Anastasía, Daniel Mamah, Charles F. Zorumski, Daniel H. Mascó, Daniel G. Herrera, Gabriel A. de Erausquin   +7 more
openalex   +1 more source

299 PRE-084, A Sigma-1 Receptor Ligand, Protects Against Excitotoxic Perinatal Brain Injury in Newborn Mice [PDF]

, 2012
Elke Griesmaier, Anna Posod, Michael L. Gross, Vera Neubauer, K. Wegleiter, Martin Hermann, M Urbanek, Matthias Keller, Ursula Kiechl‐Kohlendorfer   +8 more
openalex   +1 more source

Editorial Perspective: Smoking, vaping and mental health – a perspective on potential causal mechanisms

Journal of Child Psychology and Psychiatry, EarlyView.
This editorial perspective focuses on the complex relationship of cigarette smoking and e‐cigarette use (‘vaping’) with mental health problems. It is challenging to reliably determine the causal nature of these associations because both (e‐)smoking and mental health problems generally arise during adolescence, and both are highly multifactorial in ...
Jorien L. Treur, Jentien M. Vermeulen, Margot P. van de Weijer   +2 more
wiley   +1 more source

GENE EXPRESSION FOLLOWING TRAUMATIC BRAIN INJURY [PDF]

, 1998
The pathology which results from traumatic brain injury (TBI) have long been believed to be immediate and irreversible. However, recently it has been shown that, although the primary effects are virtually unavoidable, the secondary effects manifest ...
Malhotra, Rajiv
core   +1 more source

Molecular insights into electroreceptor ribbon synapses from differential gene expression in sturgeon lateral line organs

Journal of Anatomy, EarlyView.
The expression of various genes involved in synapse development, stability and/or function was studied in developing mechanosensory neuromasts and electrosensory ampullary organs in sterlet sturgeon. Most were shared, including Slc17a8, Slc1a3 and Nrxn3, but Cbln18 was neuromast‐restricted and Tulp1 was ampullary organ‐restricted.
Alexander S. Campbell, Martin Minařík, David Buckley, Tanmay Anand, David Gela, Martin Pšenička, Clare V. H. Baker   +6 more
wiley   +1 more source

Parallel pathways of glutamate and ATP-mediated excitotoxicity cause significant neural cell death during ischaemia: potential for novel neuroprotective strategies

, 2013
Philipp Vermehren, Robert Fern
openalex   +1 more source

Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder

Journal of Internal Medicine, EarlyView.
Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley   +1 more source

Complement component 3 (C3) expression in the hippocampus after excitotoxic injury: role of C/EBPβ [PDF]

, 2016
Elena Hernández‐Encinas, Diana Aguilar‐Morante, José Á. Morales-García, Elena Giné, Marina Sanz-SanCristóbal, Ángel Santos, Ana Pérez‐Castillo   +6 more
openalex   +1 more source