Results 151 to 160 of about 83,508 (337)
Journal of Paediatrics and Child Health, EarlyView.ABSTRACT Aim The aim of this Phase I/II open‐label study was to assess the safety and efficacy of NTI164, a novel full‐spectrum medicinal cannabis plant extract 0.08% Δ‐9‐tetrahydrocannabinol (THC), in Rett syndrome (RTT). Methods Eleven female participants (5–16 years) with a pathogenic variant in the MECP2 gene were recruited to this study, receiving
B. A. Keating +7 more
wiley +1 more source
663. Protecting the CNS from Inflammation and Excitotoxic Neuron Loss by Prior Intra Marrow Injection of a rSV40-Derived Vector Carrying an Interfering RNA Against CCR5 [PDF]
, 2008 openalex +1 more source
Photochemistry and Photobiology, EarlyView.This study evaluated the analgesic and inflammatory modulation effect of PBM using 660 nm (red) and 532 nm (green) lasers in a rat model of postoperative pain. Wistar rats underwent paw incision and received laser irradiation according to their groups.
Andréa Ribeiro Mattoso‐Câmara +5 more
wiley +1 more source
Differential Susceptibility to Excitotoxic Stress in YAC128 Mouse Models of Huntington Disease between Initiation and Progression of Disease [PDF]
, 2009 Rona K. Graham +14 more
openalex +1 more source
Optimization of photobiomodulation therapy for spinal cord injury: A review
Photochemistry and Photobiology, EarlyView.Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew +3 more
wiley +1 more source
Transfusion, EarlyView.Abstract Background Traumatic brain injury (TBI) carries significant mortality and morbidity in civilian and military populations. Current treatment guidelines for TBI are primarily supportive, and no pharmacological agent exists to attenuate the progression of brain injury.
Maxime A. Visa +9 more
wiley +1 more source
Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications
Experimental Physiology, EarlyView.Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó +1 more
wiley +1 more source
Lack of kainic acid‐induced gamma oscillations predicts subsequent CA1 excitotoxic cell death
, 2009 Seiichiro Jinde +5 more
openalex +2 more sources