Results 161 to 170 of about 46,919 (266)

Strain-Dependent Differences in Calcium Signaling Predict Excitotoxicity in Murine Hippocampal Neurons [PDF]

, 2001
C. William Shuttleworth, John A. Connor
openalex   +1 more source

Spatial Transcriptomic Analysis Reveals HDAC Inhibition Modulates Microglial Dynamics to Protect Against Ischemic Stroke in Mice

Glia, Volume 73, Issue 9, Page 1817-1840, September 2025.
Main Point Spatial transcriptomic analysis unravels the mechanisms by which HDACi ameliorates neuroinflammation and enhances neuroprotection by modulating the expression of microglial transcriptomes in the ischemic mouse brain. ABSTRACT Ischemic stroke significantly contributes to global morbidity and disability through a cascade of neurological ...
Kevin Jayaraj, Ritesh Kumar, Sukanya Shyamasundar, Thiruma V. Arumugam, Jai S. Polepalli, S. Thameem Dheen   +5 more
wiley   +1 more source

Factors Contributing to Resistance to Ischemia-Reperfusion Injury in Olfactory Mitral Cells. [PDF]

Int J Mol Sci
Lee CH, Ahn JH, Won MH.
europepmc   +1 more source

The Influence of Glutamate Receptor 2 Expression on Excitotoxicity in GluR2 Null Mutant Mice [PDF]

, 2001
Koji Iihara, Daisy T. Joo, Jeffrey T. Henderson, Rita Sattler, Franco A. Taverna, Sandra Lourensen, Beverley A. Orser, John Roder, Michael Tymianski   +8 more
openalex   +1 more source

Differential Astrocyte‐Supplied NMDAR Co‐Agonist for CA1 Versus Dentate Gyrus Long‐Term Potentiation

Hippocampus, Volume 35, Issue 5, September 2025.
ABSTRACT In the hippocampus, there is a region‐ and synapse‐specific N‐methyl‐D‐aspartate receptor (NMDAR) co‐agonist preference for induction of long‐term potentiation (LTP). Schaffer collateral (SC)‐CA1 synapses, enriched in GluN2A‐containing NMDARs, favor D‐serine, while medial perforant path (MPP) to dentate gyrus (DG) synapses that are rich in ...
Shruthi Sateesh, Wickliffe C. Abraham
wiley   +1 more source

Excitotoxic Model of Post-traumatic Syringomyelia in the Rat [PDF]

, 2001
Liqun Yang, Nigel R. Jones, Marcus A. Stoodley, Peter Blumbergs, Christopher J. Brown   +4 more
openalex   +1 more source

Brain Magnetic Resonance Imaging of Children With Molybdenum Cofactor Deficiency

Journal of Inherited Metabolic Disease, Volume 48, Issue 5, September 2025.
ABSTRACT Molybdenum cofactor deficiency (MoCD) is a rare differential diagnosis of neonatal hypoxic ischemic encephalopathy (HIE) with considerable variation in presentation and treatment outcomes. The temporospatial evolution of brain MRI appearances has not been well described.
B. C. Schwahn, R. Sinha, J. A. M. Wright, J. Pavaine   +3 more
wiley   +1 more source

A brain-accessible peptide modulates stroke inflammatory response and neurotoxicity by targeting BDNF-receptor TrkB-T1 specific interactome. [PDF]

Theranostics
Ugalde-Triviño L, Tejeda GS, Esteban-Ortega GM, Díaz-Guerra M.   +3 more
europepmc   +1 more source

Differential postreceptor signaling events triggered by excitotoxic stimulation of different ionotropic glutamate receptors in retinal neurons [PDF]

, 2001
Armanda E. Santos, Ana Luı́sa Carvalho, María Celeste Lopes, Arsélio P. Carvalho   +3 more
openalex   +1 more source

Optimized Long‐TE 1H sLASER MR Spectroscopic Imaging at 3T for Separate Quantification of Glutamate and Glutamine in Glioma

Journal of Magnetic Resonance Imaging, Volume 62, Issue 3, Page 890-901, September 2025.
ABSTRACT Background Glutamate and glutamine are critical metabolites in gliomas, each serving distinct roles in tumor biology. Separate quantification of these metabolites using in vivo MR spectroscopy (MRS) at clinical field strengths (≤ 3T) is hindered by their molecular similarity, resulting in overlapping, hence indistinguishable, spectral peaks ...
Seyma Alcicek, Michael W. Ronellenfitsch, Joachim P. Steinbach, Andrei Manzhurtsev, Dennis C. Thomas, Katharina J. Weber, Vincent Prinz, Marie‐Thérèse Forster, Elke Hattingen, Ulrich Pilatus, Katharina J. Wenger   +10 more
wiley   +1 more source