Results 171 to 180 of about 90,697 (359)
Brain Pathology, EarlyView.Elevated angiogenin levels in skeletal muscle are linked to slower disease progression, enhanced regeneration, and vascularization through satellite‐endothelial interaction during myogenesis in ALS. Angiogenin and its tiRNAs may serve as prognostic markers and therapeutic targets for ALS.
Paola Fabbrizio +13 more
wiley +1 more source
Blockade of neuronal nitric oxide synthase protects against excitotoxicity in vivo [PDF]
, 1995 Jörg B. Schulz +9 more
openalex +1 more source
Prasinezumab: A Bayesian Perspective on Its Efficacy
Movement Disorders, EarlyView.
Mirella Russo +3 more
wiley +1 more source
The Olivocerebellar Projection Mediates Ibogaine-Induced Degeneration of Purkinje Cells: A Model of Indirect, Trans-Synaptic Excitotoxicity [PDF]
, 1997 Elizabeth O’Hearn, Mark E. Molliver
openalex +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with limited treatment options. ALS pathogenesis involves intricate processes within motor neurons, characterized by dysregulated Ca2+ influx and buffering in early ALS‐affected motor neurones. This study proposes the modulation of ryanodine receptors (
Laura Moreno‐Martinez +17 more
wiley +1 more source
A Transforming Growth Factor-β Antagonist Unmasks the Neuroprotective Role of This Endogenous Cytokine in Excitotoxic and Ischemic Brain Injury [PDF]
, 1999 Antonio Ruocco +10 more
openalex +1 more source
Cell Proliferation, EarlyView.Illustration of the preparation of tFNAs‐DJ‐1 saRNAs complex and its inhibitory effects on ferroptosis in R28 and retina. ABSTRACT Retinal ischaemia/reperfusion injury (RI/RI) is the primary pathophysiological mechanism underlying retinal ischaemic diseases, potentially resulting in significant and irreversible visual impairment.
Xianggui Zhang +10 more
wiley +1 more source
AMPA receptor desensitization predicts the selective vulnerability of cerebellar Purkinje cells to excitotoxicity [PDF]
, 1995 JR Brorson +3 more
openalex +1 more source
Developmental Medicine &Child Neurology, EarlyView.Why does infantile epileptic spasms syndrome (IESS) occur with a variety of underlying conditions and why does it respond to adrenocorticotrophin hormone (ACTH)/corticosteroids? Our scoping review summarizes five hypotheses from the literature: gene/epigenetic regulation, stress/HPA axis activation, neuroinflammation/immune function, altered neuronal ...
Emily A. Innes +6 more
wiley +1 more source
Narrow temporal therapeutic window for NMDA antagonist protection against focal cerebral ischaemia
Neurobiology of Disease, 1995 N-methyl-d-aspartate (NMDA) receptor antagonists have been shown to protect against focal cerebral ischaemia when administered either before or soon after the onset of ischaemia.
Gary K. Steinberg +5 more
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