Results 181 to 190 of about 95,867 (358)
Developmental Medicine &Child Neurology, EarlyView.Why does infantile epileptic spasms syndrome (IESS) occur with a variety of underlying conditions and why does it respond to adrenocorticotrophin hormone (ACTH)/corticosteroids? Our scoping review summarizes five hypotheses from the literature: gene/epigenetic regulation, stress/HPA axis activation, neuroinflammation/immune function, altered neuronal ...
Emily A. Innes +6 more
wiley +1 more source
Correction for Scarisbrick et al., Nervous System-Specific Expression of a Novel Serine Protease: Regulation in the Adult Rat Spinal Cord by Excitotoxic Injury [PDF]
, 1998 openalex +1 more source
Immunity and neuroinflammation in early stages of life and epilepsy
Epilepsia, EarlyView.Abstract The immune system is crucial for the correct brain development, and recent findings also point toward central control of immune response. As the immune system is not fully developed at birth, the early years become an important window for infections and for the development of epilepsy.
Angelica Vega García +5 more
wiley +1 more source
Delayed Mitochondrial Dysfunction in Excitotoxic Neuron Death: CytochromecRelease and a Secondary Increase in Superoxide Production [PDF]
, 2000 C. Marc Luetjens +8 more
openalex +1 more source
Medication‐resistant epilepsy is associated with a unique gut microbiota signature
Epilepsia, EarlyView.Abstract Objective Dysfunction of the microbiota–gut–brain axis is emerging as a new pathogenic mechanism in epilepsy, potentially impacting on medication response and disease outcome. We investigated the composition of the gut microbiota in a cohort of medication‐resistant (MR) and medication‐sensitive (MS) pediatric patients with epilepsy.
Antonella Riva +14 more
wiley +1 more source
Status epilepticus in older adults: A critical review
Epilepsia, EarlyView.Abstract Older adults (≥60 years of age) have the highest incidence of status epilepticus (SE) among adults and experience the highest morbidity and mortality. SE incidence increases with age in adulthood. A recent study from Austria estimated an incidence of 89.6/100 000 and 67.6/100 000 person‐years adjusted for age and sex in women and men aged >60 ...
Matthew R. Woodward +5 more
wiley +1 more source
Cerebrospinal fluid studies in children with cerebral malaria: an excitotoxic mechanism? [PDF]
, 2000 Michael S. Dobbie +4 more
openalex +1 more source
Contribution of perineuronal nets to hyperexcitability in pilocarpine‐induced status epilepticus
Epilepsia, EarlyView.Abstract Objective Changes in extracellular matrix (ECM) and highly condensed ECM structures called perineuronal nets (PNNs) have been reported in human patients with epilepsy as well as some animal models of epilepsy. We studied potential ECM changes in a mouse model of pilocarpine‐induced status epilepticus (PISE) and their potential contributions to
AnnaLin M. Woo +3 more
wiley +1 more source