Results 1 to 10 of about 173,911 (303)

Exosomes and Exosomal miRNA in Respiratory Diseases [PDF]

open access: yesMediators of Inflammation, 2016
Exosomes are nanosized vesicles released from every cell in the body including those in the respiratory tract and lungs. They are found in most body fluids and contain a number of different biomolecules including proteins, lipids, and both mRNA and noncoding RNAs.
Shamila D. Alipoor   +5 more
openaire   +12 more sources

Intraduodenal Delivery of Exosome-Loaded SARS-CoV-2 RBD mRNA Induces a Neutralizing Antibody Response in Mice

open access: yesVaccines, 2023
Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), has presented numerous challenges to global health.
Quan Zhang   +10 more
doaj   +1 more source

Exosomes [PDF]

open access: yesCirculation Research, 2015
Nature has designed clever ways for information and material transfer between cells and for intercellular coordination. Mechanisms include direct cell contact, gap junctions, and receptor-ligand signaling. In the past decade, a particular form of exchange has gained increasing attention, and that is intercellular transfer of extracellular vesicles ...
Yin, Tintut, Linda L, Demer
openaire   +5 more sources

Neutrophil membrane engineered HucMSC sEVs alleviate cisplatin-induced AKI by enhancing cellular uptake and targeting

open access: yesJournal of Nanobiotechnology, 2022
Human umbilical cord mesenchymal stem cells-derived small extracellular vesicles (hucMSC-sEVs) have been demonstrated as a therapeutic agent to prevent and treat cisplatin-induced acute kidney injury (AKI).
Peipei Wu   +11 more
doaj   +1 more source

Urinary Exosomes [PDF]

open access: yesThe Scientific World JOURNAL, 2009
Exosomes are nanovesicles of endocytic origin that are secreted into the extracellular space or body fluids when a multivesicular body (MVB) fuses with the cell membrane. Interest in exosomes intensified after their description in antigen-presenting cells and the observation that they can significantly moderate immune responsesin vivo.
Irena Dimov   +2 more
openaire   +3 more sources

MSC-Derived Extracellular Vesicle-Delivered L-PGDS Inhibit Gastric Cancer Progression by Suppressing Cancer Cell Stemness and STAT3 Phosphorylation

open access: yesStem Cells International, 2022
Mesenchymal stem cell- (MSC-) derived extracellular vesicles (EVs) serving as delivery system have attracted extensive research interest, especially in cancer therapy.
Benshuai You   +6 more
doaj   +1 more source

Exosomics

open access: yesEMBnet.journal, 2020
Extracellular vesicles have been the focus of a large number of studies in the past five years. Exosomes, a subgroup of extracellular vesicles, are of particularly high interest because they partake in a wide number of biological pathways.  Produced by a variety of cells, exosomes have an important role in both physiological and pathological conditions.
Mitsis, Thanasis   +6 more
openaire   +4 more sources

Roles of Mesenchymal Stem Cell-Derived Exosomes in Cancer Development and Targeted Therapy

open access: yesStem Cells International, 2021
Exosomes have emerged as a new drug delivery system. In particular, exosomes derived from mesenchymal stem cells (MSCs) have been extensively studied because of their tumor-homing ability and yield advantages.
Zixuan Sun   +7 more
doaj   +1 more source

Exosomes from Human Adipose Tissue-Derived Mesenchymal Stem Cells Promote Epidermal Barrier Repair by Inducing de Novo Synthesis of Ceramides in Atopic Dermatitis. [PDF]

open access: yes, 2020
Atopic dermatitis (AD) is a multifactorial, heterogeneous disease associated with epidermal barrier disruption and intense systemic inflammation. Previously, we showed that exosomes derived from human adipose tissue-derived mesenchymal stem cells (ASC ...
Cho, Byong Seung   +19 more
core   +1 more source

Orally Administered Bifidobacterium adolescentis Diminishes Serum Glutamate Concentration in Mice

open access: yesMicrobiology Spectrum, 2023
Several studies have described the contribution of glutamate-transforming microbiota to the development of chronic ailments. For instance, the blood concentration of glutamate is higher in some patients with fibromyalgia, chronic fatigue, and pain ...
Felix Royo   +9 more
doaj   +1 more source

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