Results 21 to 30 of about 158,436 (362)
Roles of Mesenchymal Stem Cell-Derived Exosomes in Cancer Development and Targeted Therapy
Stem Cells International, 2021 Exosomes have emerged as a new drug delivery system. In particular, exosomes derived from mesenchymal stem cells (MSCs) have been extensively studied because of their tumor-homing ability and yield advantages.
Zixuan Sun +7 more
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A review on exosomes application in clinical trials: perspective, questions, and challenges
Cell Communication and Signaling, 2022 Background Exosomes are progressively known as significant mediators of cell-to-cell communication. They convey active biomolecules to target cells and have vital functions in several physiological and pathological processes, and show substantial promise
J. Rezaie +2 more
semanticscholar +1 more source
Emerging role of exosomes in cancer progression and tumor microenvironment remodeling
Journal of Hematology & Oncology, 2022 Cancer is one of the leading causes of death worldwide, and the factors responsible for its progression need to be elucidated. Exosomes are structures with an average size of 100 nm that can transport proteins, lipids, and nucleic acids.
Mahshid Deldar Abad Paskeh +18 more
semanticscholar +1 more source
Exosomes—Nature’s Lipid Nanoparticles, a Rising Star in Drug Delivery and Diagnostics
ACS Nano, 2022 Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer membrane and secreted by most eukaryotic cells. They represent a route of intercellular communication and participate in a wide variety of physiological and ...
Rumiana Tenchov +5 more
semanticscholar +1 more source
Orally Administered Bifidobacterium adolescentis Diminishes Serum Glutamate Concentration in Mice
Microbiology Spectrum, 2023 Several studies have described the contribution of glutamate-transforming microbiota to the development of chronic ailments. For instance, the blood concentration of glutamate is higher in some patients with fibromyalgia, chronic fatigue, and pain ...
Felix Royo +9 more
doaj +1 more source
Metabolites, 2022 Steroid hormones play a vital role in the regulation of cellular processes, and dysregulation of these metabolites can provoke or aggravate pathological issues, such as autoimmune diseases and cancer.
Guillermo Bordanaba-Florit +4 more
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Advancement of science, 2022 Electroconductive hydrogels are very attractive candidates for accelerated spinal cord injury (SCI) repair because they match the electrical and mechanical properties of neural tissue.
Lei Fan +15 more
semanticscholar +1 more source
Extracellular vesicles in idiopathic pulmonary fibrosis: pathogenesis and therapeutics
Inflammation and Regeneration, 2022 Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease that occurs due to increased fibrosis of lung tissue in response to chronic injury of the epithelium.
Yu Fujita
doaj +1 more source
Frontiers in Oncology, 2020 Neutrophils are prominent components of solid tumors and exhibit distinct phenotypes in different tumor milieu. We have previously shown that tumor extracellular vesicles (EVs) could induce pro-tumor activation of neutrophils; however, the role of tumor ...
Yinghong Shi +19 more
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Therapeutic Advances of Stem Cell-Derived Extracellular Vesicles in Regenerative Medicine
Cells, 2020 Extracellular vesicles (EVs), which are the main paracrine components of stem cells, mimic the regenerative capacity of these cells. Stem cell-derived EVs (SC-EVs) have been used for the treatment of various forms of tissue injury in preclinical trials ...
Lei Yin +8 more
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