Results 21 to 30 of about 202,629 (353)

Extracellular vesicles from hair follicle-derived mesenchymal stromal cells: isolation, characterization and therapeutic potential for chronic wound healing

Stem Cell Research & Therapy, 2022
Background Mesenchymal stromal cells (MSCs) and their extracellular vesicles (MSC-EVs) have demonstrated to elicit immunomodulatory and pro-regenerative properties that are beneficial for the treatment of chronic wounds.
Kevin Las Heras, Félix Royo, Clara Garcia-Vallicrosa, Manoli Igartua, Edorta Santos-Vizcaino, Juan M. Falcon-Perez, Rosa Maria Hernandez   +6 more
doaj   +1 more source

P-66 COULD PROTEIN CONTENT OF URINARY EXTRACELLULAR VESICLES BE USEFUL TO DETECT CIRRHOSIS IN ALCOHOLIC LIVER DISEASE?

Annals of Hepatology, 2021
Introduction: Alcohol abuse has a high impact on the mortality and morbidity related to a great number of diseases and is responsible for the development of alcoholic liver disease (ALD).
E. Gonzalez, M. Azkargorta, C. Garcia-Vallicrosa, J. Prieto-Elordui, F. Elortza, S. Blanco-Sampascual, J.M. Falcon-Perez   +6 more
doaj   +1 more source

Exosome-mediated Transfer of αvβ3 Integrin from Tumorigenic to Nontumorigenic Cells Promotes a Migratory Phenotype. [PDF]

, 2016
The αvβ3 integrin is known to be highly upregulated during cancer progression and promotes a migratory and metastatic phenotype in many types of tumors.
Fedele, Carmine, Keen, James H., Languino, Lucia R., Lu, Huimin, Nevalainen, Marja T., Singh, Amrita   +5 more
core   +2 more sources

Tuberous Sclerosis Complex cell‐derived EVs have an altered protein cargo capable of regulating their microenvironment and have potential as disease biomarkers

Journal of Extracellular Vesicles, 2023
Hyperactivation of mechanistic target of rapamycin complex 1 (mTORC1) is a feature of many solid tumours and is a key pathogenic driver in the inherited condition Tuberous Sclerosis Complex (TSC).
Muireann Ní Bhaoighill, Juan M. Falcón‐Pérez, Félix Royo, Andrew R. Tee, Jason P. Webber, Elaine A. Dunlop   +5 more
doaj   +1 more source

Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells. [PDF]

, 2019
HIV infection has a profound effect on "bystander" cells causing metabolic co-morbidities. This may be mediated by exosomes secreted by HIV-infected cells and containing viral factors.
Brichacek, Beda, Bukrinsky, Michael, Ditiatkovski, Michael, Dragoljevic, Dragana, Dubrovsky, Larisa, Fu, Ying, Hoang, Anh, Horvath, Anelia, Low, Hann, Meikle, Peter J, Miller, Yury I, Mukhamedova, Nigora, Murphy, Andrew, Ohkawa, Ryunosuke, Pushkarsky, Tatiana, Sviridov, Dmitri   +15 more
core   +3 more sources

Abundance of Cytochromes in Hepatic Extracellular Vesicles Is Altered by Drugs Related With Drug‐Induced Liver Injury

Hepatology Communications, 2018
Drug‐induced liver injury (DILI) is a serious worldwide health problem that accounts for more than 50% of acute liver failure. There is a great interest in clinical diagnosis and pharmaceutical industry to elucidate underlying molecular mechanisms and ...
Laura Palomo, Justyna Emilia Mleczko, Mikel Azkargorta, Javier Conde‐Vancells, Esperanza González, Felix Elortza, Félix Royo, Juan M. Falcon‐Perez   +7 more
doaj   +1 more source

Extracellular vesicles released by steatotic hepatocytes alter adipocyte metabolism

Journal of Extracellular Biology, 2022
The composition of extracellular vesicles (EVs) is altered in many pathological conditions, and their molecular content provides essential information on features of parent cells and mechanisms of crosstalk between cells and organs.
J.E. Mleczko, F. Royo, I. Samuelson, M. Clos‐Garcia, C. Williams, D. Cabrera, M. Azparren‐Angulo, E. Gonzalez, C. Garcia‐Vallicrosa, S. Carobbio, S. Rodriguez‐Cuenca, M. Azkargorta, S. vanLiempd, F. Elortza, A. Vidal‐Puig, S. Mora, J.M. Falcon‐Perez   +16 more
doaj   +1 more source

Digital detection of exosomes by interferometric imaging [PDF]

, 2016
Exosomes, which are membranous nanovesicles, are actively released by cells and have been attributed to roles in cell-cell communication, cancer metastasis, and early disease diagnostics.
Benussi, Luisa, Bettotti, Paolo, Chiari, Marcella, Ciani, Miriam, Cretich, Marina, Daaboul, George G., Freedman, David S., Gagni, Paola, Ghidoni, Roberta, Ozkumur, Ayca Yalcin, Piotto, Chiara, Prosperi, Davide, Santini, Benedetta, Unlu, M. Selim   +13 more
core   +2 more sources

Circular RNA CDR1as Inhibits the Metastasis of Gastric Cancer through Targeting miR-876-5p/GNG7 Axis

Gastroenterology Research and Practice, 2021
Circular RNA CDR1as has been demonstrated to participate in various cancer progressions as miRNA sponges. The exact underlying mechanisms of CDR1as on gastric cancer (GC) metastasis remain unknown. Here, we found that CDR1as knockdown facilitated GC cell
Jiajia Jiang, Rong Li, Junyi Wang, Jie Hou, Hui Qian, Wenrong Xu   +5 more
doaj   +1 more source

Microencapsulation technology by nature: Cell derived extracellular vesicles with therapeutic potential [PDF]

, 2013
Cell derived extracellular vesicles are submicron structures surrounded by phospholipid bilayer and released by both prokaryotic and eukaryotic cells.
Buzás, E., Falus, A., Kittel, Ágnes
core   +1 more source