Results 21 to 30 of about 165,277 (308)

Exosomes to the Rescue [PDF]

open access: yesJournal of the American Society of Nephrology, 2015
Acute kidney injury, AKI, is relatively common in the hospital setting, and beyond the identification of the underlying cause and supportive measures, little can be done to facilitate healing of the compromised kidney.
Christopher J. Ward   +1 more
openaire   +3 more sources

Hallmarks of Exosomes

open access: yesFuture Science OA, 2021
Exosomes are a new horizon in modern therapy, presenting exciting new opportunities for advanced drug delivery and targeted release. Exosomes are small extracellular vesicles with a size range of 30-100 nm, secreted by all cell types in the human body and carrying a unique collection of DNA fragments, RNA species, lipids, protein biomarkers ...
openaire   +4 more sources

Quantification of Exosomes [PDF]

open access: yesJournal of Cellular Physiology, 2017
Exosomes are released by cells as self‐contained vesicles with an intact lipid bilayer that encapsulates a small portion of the parent cell. Exosomes have been studied widely as information‐rich sources of potential biomarkers that can reveal cellular physiology.
Robert A. Star   +3 more
openaire   +3 more sources

The exosome, plugged [PDF]

open access: yesEMBO reports, 2007
The correct processing, quality control and turnover of cellular RNA molecules is crucial to many aspects of cell physiology. The exosome—a large molecular assembly with exoribonuclease activity—has emerged as a crucial component in many, if not most, stages of RNA metabolism, including degradation and maturation of ribosomal RNA, RNA quality control ...
Karl-Peter Hopfner, Sophia Hartung
openaire   +3 more sources

Emerging Exosomes and Exosomal MiRNAs in Spinal Cord Injury [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2021
Acute spinal cord injury (SCI) is a serious traumatic event to the spinal cord with considerable morbidity and mortality. This injury leads to short- and long-term variations in the spinal cord, and can have a serious effect on the patient’s sensory, motor, or autonomic functions.
Zhihan Zhu   +5 more
openaire   +4 more sources

Exosomes in cancer

open access: yes, 2021
Exosomes are small extracellular vesicles released by cells under physiological and pathological conditions. There is emerging evidence associating exosomes with tumorigenesis. They carry cargo (DNA, RNA, miRNA and protein) pertaining to the cell of origin and play a key role in intercellular communication, influencing several cellular processes ...
José Miguel Amenábar   +4 more
openaire   +4 more sources

The RNA exosome and RNA exosome-linked disease [PDF]

open access: yesRNA, 2017
The RNA exosome is an evolutionarily conserved, ribonuclease complex that is critical for both processing and degradation of a variety of RNAs. Cofactors that associate with the RNA exosome likely dictate substrate specificity for this complex. Recently, mutations in genes encoding both structural subunits of the RNA exosome and its cofactors have been
Derrick J. Morton   +5 more
openaire   +3 more sources

Exosome-mediated Transfer of αvβ3 Integrin from Tumorigenic to Nontumorigenic Cells Promotes a Migratory Phenotype. [PDF]

open access: yes, 2016
The αvβ3 integrin is known to be highly upregulated during cancer progression and promotes a migratory and metastatic phenotype in many types of tumors.
Fedele, Carmine   +5 more
core   +2 more sources

Antibody-loading of biological nanocarrier vesicles derived from red-blood-cell membranes [PDF]

open access: yesarXiv, 2023
Antibodies, disruptive potent therapeutic agents against pharmacological targets, face a barrier crossing immune-system and cellular-membranes. To overcome these, various strategies have been explored including shuttling via liposomes or bio-camouflaged nanoparticles.
arxiv  

Plasmonic nano-aperture label-free imaging [PDF]

open access: yes, 2020
Label-free observation of nanoparticles by far-field optical microscopy is challenging because their ability to scatter or absorb light dramatically diminishes with decreasing size. Surface plasmon resonance (SPR) and localized surface plasmon resonance (LSPR) imaging have shown promises and respective limitations.
arxiv   +1 more source

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