Results 111 to 120 of about 5,529,456 (280)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Crowd-counting technology within the Smart City context: understanding, trust, and acceptance

open access: yesFrontiers in Psychology
In city centers worldwide, including the UNESCO World Heritage Site of Bamberg’s old town in Germany, alleviating pedestrian overcrowding is a pressing concern.
Theresa Waclawek   +3 more
doaj   +1 more source

Tonal music theory: A psychoacoustic explanation? [PDF]

open access: yes, 2010
From the seventeenth century to the present day, tonal harmonic music has had a number of invariant properties such as the use of specific chord progressions (cadences) to induce a sense of closure, the asymmetrical privileging of certain progressions ...
Milne, Andrew J.
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Is there Verification in Theology?

open access: yesOpen Theology, 2017
Critical realism (CR) has served as a benchmark in science-theology dialogue as a way of determining similar rational structures in these disciplines.
Allen Paul L.
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Plato Seeking for “One Real Explanation” in Phaedo [PDF]

open access: yesJournal of Philosophical Investigations, 2018
What this essay is to discuss is Plato''s theory of explanation in Phaedo. In this dialogue, we observe that Socrates criticizes both the natural scientists’ explanations and Anaxagoras’ theory of Mind since he thinks they could not explain all things ...
محمد باقر قمی   +1 more
doaj  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Defying explanation [PDF]

open access: yesBritish Dental Journal, 2006
J L, Gibbs, M, Cowie, N, Brooks
openaire   +2 more sources

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