CD47 interactions with exportin-1 limit the targeting of m<sup>7</sup>G-modified RNAs to extracellular vesicles. [PDF]
Kaur S +14 more
europepmc +1 more source
Background: KRAS G12C-mutant advanced non-small cell lung cancer (NSCLC) is currently treated with KRAS G12C covalent inhibitors, such as sotorasib, or RAS (ON) G12-selective inhibitors; however, response rates and progression-free survival remain ...
Jèssica González +13 more
doaj +1 more source
STAT6 is a cargo of exportin 1: Biological relevance in primary mediastinal B-cell lymphoma
International audiencePrimary mediastinal B-cell lymphoma (PMBL) is a distinct B-cell lymphoma subtype with unique clinicopathological and molecular features.
Miloudi, Hadjer +7 more
core +1 more source
Nuclear Exportin 1 (XPO1) Binds to the Nuclear Localization/Export Signal of the Turnip Mosaic Virus NIb to Promote Viral Infection. [PDF]
Zhang M +8 more
europepmc +1 more source
Enhanced Activity of Exportin-1/CRM1 in Neurons Contributes to Autophagy Dysfunction and Senescent Features in Old Mouse Brain. [PDF]
Gorostieta-Salas E +5 more
europepmc +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
BMI‐1 (B‐cell‐specific Moloney murine leukemia virus integration site 1) has been implicated in both normal and cancer cell biology. While the canonical function of BMI‐1 involves epigenetic repression, novel extranuclear functions have been recently ...
Banlanjo Umaru +6 more
doaj +1 more source
Exportin 1 (XPO1; CRM1); histone deacetylase 1 (HDAC1) [PDF]
openaire +1 more source
Verdinexor, a Selective Inhibitor of Nuclear Exportin 1, Inhibits the Proliferation and Migration of Esophageal Cancer via XPO1/c-Myc/FOSL1 Axis. [PDF]
Ou L +13 more
europepmc +1 more source
Exportin 1 Inhibitor Combined With Venetoclax Induces Apoptosis in Myelodysplastic Syndrome by Mitochondria-Induced Apoptosis Pathway. [PDF]
Liu X +8 more
europepmc +1 more source
Combination effect of Exportin 1 inhibitor (KPT-335) with doxorubicin or vincristine in canine lymphoma cell lines. [PDF]
Primarizky H +4 more
europepmc +1 more source

