Results 121 to 130 of about 29,704,271 (175)

CD47 interactions with exportin-1 limit the targeting of m<sup>7</sup>G-modified RNAs to extracellular vesicles. [PDF]

open access: yesJ Cell Commun Signal, 2022
Kaur S   +14 more
europepmc   +1 more source

Anticancer effects of an XPO1 inhibitor (selinexor) with sotorasib following omeprazole preconditioning in KRAS G12C-mutant non-small cell lung cancer cells in vitro and in a mouse tumor xenograft

open access: yesNeoplasia: An International Journal for Oncology Research
Background: KRAS G12C-mutant advanced non-small cell lung cancer (NSCLC) is currently treated with KRAS G12C covalent inhibitors, such as sotorasib, or RAS (ON) G12-selective inhibitors; however, response rates and progression-free survival remain ...
Jèssica González   +13 more
doaj   +1 more source

STAT6 is a cargo of exportin 1: Biological relevance in primary mediastinal B-cell lymphoma

open access: yes, 2018
International audiencePrimary mediastinal B-cell lymphoma (PMBL) is a distinct B-cell lymphoma subtype with unique clinicopathological and molecular features.
Miloudi, Hadjer   +7 more
core   +1 more source

Enhanced Activity of Exportin-1/CRM1 in Neurons Contributes to Autophagy Dysfunction and Senescent Features in Old Mouse Brain. [PDF]

open access: yesOxid Med Cell Longev, 2021
Gorostieta-Salas E   +5 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio
BMI‐1 (B‐cell‐specific Moloney murine leukemia virus integration site 1) has been implicated in both normal and cancer cell biology. While the canonical function of BMI‐1 involves epigenetic repression, novel extranuclear functions have been recently ...
Banlanjo Umaru   +6 more
doaj   +1 more source

Verdinexor, a Selective Inhibitor of Nuclear Exportin 1, Inhibits the Proliferation and Migration of Esophageal Cancer via XPO1/c-Myc/FOSL1 Axis. [PDF]

open access: yesInt J Biol Sci, 2022
Ou L   +13 more
europepmc   +1 more source

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