Results 101 to 110 of about 12,090 (148)

A new therapeutic approach to <i>KRAS</i> mutant non-small cell lung cancer: the emerging role of exportin 1 inhibition. [PDF]

Transl Lung Cancer Res
von Itzstein MS, Gerber DE.
europepmc   +1 more source

Exportin 1 inhibitor KPT‑330 reverses oxaliplatin resistance via p53 nuclear retention in colorectal cancer. [PDF]

Int J Mol Med
Lai C, Jia X, Chen Y, Chen K, Wang F, Zhang Q, Xiang X, Chen ZS, Xu L, Dai S.   +9 more
europepmc   +1 more source

Exportin-1 functions as an adaptor for transcription factor-mediated docking of chromatin at the nuclear pore complex. [PDF]

Mol Cell
Ge T, Brickner DG, Zehr K, VanBelzen DJ, Zhang W, Caffalette C, Moeller GC, Ungerleider S, Marcou N, Jacob A, Nguyen VQ, Chait B, Rout MP, Brickner JH.   +13 more
europepmc   +1 more source

Chromosome Maintenance Region 1 (CRM1, also called exportin 1) [PDF]

, 2008
openaire   +1 more source

Exportin 1 governs the immunosuppressive functions of myeloid-derived suppressor cells in tumors through ERK1/2 nuclear export. [PDF]

Cell Mol Immunol
Daneshmandi S, Yan Q, Choi JE, Katsuta E, MacDonald CR, Goruganthu M, Roberts N, Repasky EA, Singh PK, Attwood K, Wang J, Landesman Y, McCarthy PL, Mohammadpour H.   +13 more
europepmc   +1 more source

Exportin 1 Inhibition Induces Nerve Growth Factor Receptor Expression to Inhibit the NF-κB Pathway in Preclinical Models of Pediatric High-Grade Glioma. [PDF]

Mol Cancer Ther, 2020
DeSisto JA, Flannery P, Lemma R, Pathak A, Mestnik S, Philips N, Bales NJ, Kashyap T, Moroze E, Venkataraman S, Kung AL, Carter BD, Landesman Y, Vibhakar R, Green AL.   +14 more
europepmc   +1 more source

Unbiased screening reveals that blocking exportin 1 overcomes resistance to PI3Kα inhibition in breast cancer. [PDF]

Signal Transduct Target Ther, 2019
Liu XL, Wang BB, Wang Y, Wang YX, Yang CH, Tan C, Zhang X, He QJ, Ding J, Meng LH.   +9 more
europepmc   +1 more source

Phase I/II Trial of Exportin 1 Inhibitor Selinexor plus Docetaxel in Previously Treated, Advanced KRAS-Mutant Non-Small Cell Lung Cancer. [PDF]

Clin Cancer Res
von Itzstein MS, Burns TF, Dowell JE, Horn L, Camidge DR, York SJ, Eaton KD, Kyle K, Fattah F, Liu J, Mu-Mosley H, Gupta A, Nadeem U, Gao A, Zhang S, Gerber DE.   +15 more
europepmc   +1 more source

Correction: Targeting mantle cell lymphoma metabolism and survival through simultaneous blockade of mTOR and nuclear transporter exportin-1. [PDF]

Oncotarget, 2019
Sekihara K, Saitoh K, Han L, Ciurea S, Yamamoto S, Kikkawa M, Kazuno S, Taka H, Kaga N, Arai H, Miida T, Andreeff M, Konopleva M, Tabe Y.   +13 more
europepmc   +1 more source

Inhibition of exportin-1 function results in rapid cell cycle-associated DNA damage in cancer cells. [PDF]

Oncotarget, 2017
Burke RT, Marcus JM, Orth JD.
europepmc   +1 more source