Results 41 to 50 of about 70,079 (283)

Regulatory Variation at Glypican-3 Underlies a Major Growth QTL in Mice [PDF]

, 2005
The genetic basis of variation in complex traits remains poorly understood, and few genes underlying variation have been identified. Previous work identified a quantitative trait locus (QTL) responsible for much of the response to selection on growth in ...
Liu, X, Rhind, Susan; id_orcid, Denny Paul, Verma, V, Susan Rhind, Keightley, Peter, Fiona Oliver, Christians, Julian, Xiaojun Liu, Susan Rhind (58953), Verma Vinesh, Steve D M Brown, Peter D. Keightley, Claire Davison (58955), Claire Davison, Steve D. M Brown (58956), Peter D Keightley, Denny, Paul, Davison Claire, Vinesh Verma, Steve D. M. Brown, Julian K Christians (58951), Vinesh Verma (58954), Oliver Fiona, Brown, Steve, Peter D Keightley (6249), Liu Xiaojun, Oliver, Fiona, Paul Denny (1194), Paul Denny, Christians Julian K, Davison, C, Julian K. Christians, Keightley Peter D, Rhind Susan, Brown Steve D. M, Julian K Christians, Fiona Oliver (58950), Xiaojun Liu (58952)   +38 more
core   +1 more source

Multiple locus linkage analysis of genomewide expression in yeast. [PDF]

PLoS Biology, 2005
With the ability to measure thousands of related phenotypes from a single biological sample, it is now feasible to genetically dissect systems-level biological phenomena.
John D Storey, Joshua M Akey, Leonid Kruglyak   +2 more
doaj   +2 more sources

Genome-wide expression quantitative trait loci (eQTL) analysis in maize

BMC Genomics, 2011
Background Expression QTL analyses have shed light on transcriptional regulation in numerous species of plants, animals, and yeasts. These microarray-based analyses identify regulators of gene expression as either cis-acting factors that regulate ...
Beatty Mary, Luck Stanley, Holloway Beth, Rafalski J-Antoni, Li Bailin   +4 more
doaj   +1 more source

Using transcriptome profiling to characterize QTL regions on chicken chromosome 5 [PDF]

, 2009
Background Although many QTL for various traits have been mapped in livestock, location confidence intervals remain wide that makes difficult the identification of causative mutations. The aim of this study was to test the contribution of microarray data
Désert Colette, Behnam Abasht, Sophie Leroux, Demeure Olivier, Pitel, Frédérique, Guillaume Le Mignon, Desert, C., Le Mignon, Guillaume, Le Mignon Guillaume, Pitel, F., Pascale Le Roy, Gregory Guernec, Douaire Madeleine, Lagarrigue Sandrine, Leroux, S., Désert, Colette, Lagarrigue, S., Demeure, O., Abasht, B., Colette Désert, Frédérique Pitel, Leroux, Sophie, Le Roy, P., Sandrine Lagarrigue, Le Roy, Pascale, Lagarrigue, Sandrine, Olivier Demeure, Le Mignon, G., Pitel Frédérique, Leroux Sophie, Abasht, Behnam, Douaire, M., Guernec, Gregory, Douaire, Madeleine, Madeleine Douaire, Guernec Gregory, Demeure, Olivier, Abasht Behnam, Guernec, G., Le Roy Pascale   +39 more
core   +1 more source

Genome-Wide Expression Quantitative Trait Loci Analysis Using Mixed Models

Frontiers in Genetics, 2018
Expression quantitative trait loci (eQTLs) are important for understanding the genetic basis of cellular activities and complex phenotypes. Genome-wide eQTL analyses can be effectively conducted by employing a mixed model. The mixed model includes random
Chaeyoung Lee
doaj   +1 more source

Expression quantitative trait loci for PI3K/AKT pathway

Medicine, 2017
A genome-wide association study (GWAS) was conducted to identify expression quantitative trait loci (eQTLs) for the genes involved in phosphatidylinositol-3-kinase/v-akt murine thymoma viral oncogene homolog (PI3K/AKT) pathway.Data on mRNA expression of 341 genes in lymphoblastoid cell lines of 373 Europeans recruited by the 1000 Genomes Project using ...
Ryu, Dongchan, Lee, Chaeyoung
openaire   +2 more sources

Trait-trait dynamic interaction: 2D-trait eQTL mapping for genetic variation study

BMC Genomics, 2008
Background Many studies have shown that the abundance level of gene expression is heritable. Analogous to the traditional genetic study, most researchers treat the expression of one gene as a quantitative trait and map it to expression quantitative trait
Sun Wei, Yuan Shinsheng, Li Ker-Chau
doaj   +1 more source

Transcriptomic characterization of two major Fusarium resistance quantitative trait loci (QTLs), Fhb1 and Qfhs.ifa-5A, identifies novel candidate genes [PDF]

, 2013
Fusarium head blight, caused by Fusarium graminearum, is a devastating disease of wheat. We developed near-isogenic lines (NILs) differing in the two strongest known F.
Wiesenberger, Gerlinde, Lemmens, Marc, Buerstmayr, Hermann, Schweiger, W. (Wolfgang), Steiner, B. (Barbara), Jia, Haiyan, Siegwart, Gerald, Berthiller, Franz, Adam, G. (Gerhard), Kreil, David, Ametz, Christian, Muehlbauer, Gary J.   +11 more
core   +1 more source

Expression quantitative trait loci (eQTL) associated with worm burden.

, 2023
Expression quantitative trait loci (eQTL) associated with worm burden.
Nathan J. Dunton (17512885), Enock Matovu (150725), Oscar Asanya Nyangiri (13162895), Joyce Namulondo (6954626), Barbara Nerima (370317), Alex Boobo (13162898), Miriam Casacuberta-Partal (8605314), Moses Adriko (233688), Alison Elliott (6317936), Jacent Nassuuna (7507901), Mark Kristiansen (8666934), Magambo Phillip Kimuda (4059541), Harry Noyes (121595), Gaganjit Kaur Madhan (17011419), Anna Kitibwa (13162892), Julius Mulindwa (252110)   +15 more
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Gene and QTL detection in a three-way barley cross under selection by a mixed model with kinship information using SNPs [PDF]

, 2011
Quantitative trait locus (QTL) detection is commonly performed by analysis of designed segregating populations derived from two inbred parental lines, where absence of selection, mutation and genetic drift is assumed.
Casas, Ana M., Ramsay, L., Fred A. van Eeuwijk, Mónica Elía, Bhat, Prasanna R., Malosetti, Marcos, Molina-Cano, José-Luis, Eeuwijk, F.A., van, Martin P. Boer, Luke Ramsay, van Eeuwijk, F.A., Molina-Cano, J.L., Elía, Mónica, Marian Moralejo, Ramsay, Luke, Boer, M., Eeuwijk, Fred A. van, Moralejo, Marian, Ramsay, Luke D., Ana M. Casas, Molina-Cano, José Luis, José-Luis Molina-Cano, Boer, Martin P., Moralejo, María Ángeles, Marcos Malosetti, Malosetti, M., Casas Cendoya, Ana María, Prasanna R. Bhat, Bhat, P., Casas, A., Elia, M., van Eeuwijk, Fred A.   +31 more
core   +1 more source