Results 31 to 40 of about 70,079 (283)

Quantitative Trait Locus and Genetical Genomics Analysis Identifies Putatively Causal Genes for Fecundity and Brooding in the Chicken

G3: Genes, Genomes, Genetics, 2016
Life history traits such as fecundity are important to evolution because they make up components of lifetime fitness. Due to their polygenic architectures, such traits are difficult to investigate with genetic mapping.
Martin Johnsson, Kenneth B. Jonsson, Leif Andersson, Per Jensen, Dominic Wright   +4 more
doaj   +1 more source

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. [PDF]

, 2014
Age at menarche is a marker of timing of puberty in females. It varies widely between individuals, is a heritable trait and is associated with risks for obesity, type 2 diabetes, cardiovascular disease, breast cancer and all-cause mortality.
Paternoster, Lavinia, Byrne, E.M. (Enda), Wolffenbuttel, B.H.R. (Bruce H. R.), Wolffenbuttel, Bruce H. R., Yerges-Armstrong, L.M. (Laura), Pylkaes, Katri, Ridker, P.M., Knight, Julia A., Marek Zygmunt, Ingelsson, E., Michael J. Econs, Anton-Culver, H., Sanna, Serena, Murray, A, Storniolo, A.M., McCarthy, Mark I, Boerwinkle, E., Snieder, Harold; id_orcid, Anneli Pouta, Corre, T, Ganna, A, Gudbjartsson, D.F. (Daniel), Amin, N. (Najaf), García-Closas, M, Bolla, Manjeet K, Mangino, M., Kosma, V.M., Bandinelli, S, Econs, M.J. (Michael), Beckmann, Matthias W., Koller, DL, Rudolph, A. (Anja), Sanna, S., Heli Nevanlinna, Rose, LM, Uitterlinden, Andre G., Andrew C. Heath, David Karasik, Smith, AV, Schmidt, Marjanka K., Couch, F.J. (Fergus), Coviello, A.D., Alizadeh, Behrooz Z., Chang Claude, Jenny, Per Hall, Paolo Peterlongo, Uitterlinden, André G, Streeten, Elizabeth A., Perry, J.R., Zoltan Kutalik, Bonanni, Bernardo, Lambrechts, D., John P. Rice, Järvelin, MR, Hopper, JL, Kutalik, Zoltan, Davey Smith, George, Stefansson, K, Willemsen, G.A.H.M. (Gonneke), Czene, Kamila, McMahon, G, Lawlor, Debbie, Gasparini, P, Kosma, V-M, Pylkaes, K, de Geus, Eco E.J., Kjellqvist, Sanela, Dennis, J. (Joe), Rose, Lynda M, Timpson, Nicholas J, Montgomery, G.W., Gisli Masson, Hofman, A., Bierut, L.J., Harris, T.B. (Tamara), Smith, Albert V, Wolffenbuttel, Bruce Hr, Melanie Waldenberger, Lunetta, KL, Douglas F. Easton, Milani, L., Veli-Matti Kosma, Study, AOC, Day, Felix, Nohr, EA, Johnson, A.D. (Andrew), Davey Smith, G., de Geus, E.J., Econs, MJ, Rose, L.M. (Lynda), Paternoster, L., Pylkäs, Katri, Smith, GD, Rivadeneira, F, Benítez, J. (Javier), Ulivi, S. (Shelia), Anton-Culver, H. (Hoda), Murabito, J. (Joanne), Pharoah, P.D., Hooning, MJ, Bojesen, S.E., Lindblom, A., Lavinia Paternoster, Strachan, David P., Salomaa, Veikko, Ong, KK, Lude Franke, Smith, G., Alizadeh, B.Z., Tune H. Pers, Ingelsson, Erik, Craig E. Pennell, Garcia-Closas, M., Econs, M.J., Järvelin, M.-R., Stöckl, Doris, Andres Metspalu, Stampfer, M.J. (Meir J.), Kyriaki Michailidou, Ulivi, S, Ellen W. Demerath, et al., Andrew D. Johnson, Heath, AndrewC., McCarthy, MI, Foroud, Tatiana, Milne, R.L., Hopper, J.L., Cox, A, Franceschini, N. (Nora), García Closas, Montserrat, Schlessinger, D. (David), Bojesen, Stig E., Nolte, Ilja M, Sorensen, TIA, Garcia, Melissa E., Koller, D.L., Völzke, H. (Henry), Milne, Roger L, Peterlongo, Paolo, de Geus, EE, Pers, TH, Brauch, H, Pharoah, P.D.P., Mannermaa, A. (Arto), Franceschini, N, Martin, Nicholas G, Melbye, Mads, de Geus, E.E., Chasman, Daniel I., Cox, Angela, Yerges-Armstrong, Laura M., Wright, MJ, Fernando Rivadeneira, Magnusson, Patrik K., Evelin Mihailov, Gieger, C. (Christian), Yerges Armstrong, Laura M., George Davey Smith, Sørensen, T.I.A., Marjanka K. Schmidt, Stampfer, Meir J., Erin K. Wagner, Ong, K.K., Nicholas G. Martin, Wareham, N.J., Nicholas J. Timpson, McArdle, Patrick F., Winqvist, Robert, Mangino, M, Streeten, Elizabeth A, Guo, S. (Suiqun), Giles, GG, Tsernikova, N. (Natalia), Pennell, Craig E, Robino, A, Hermann Brenner, Nicholas J. Wareham, Chen, J. (Jinhui), Loos, Ruth J. F., Pedersen, Nancy L., Thompson, DJ, Heath, A.C., Johan G. Eriksson, Järvelin, Marjo-Riitta, Hall, Per, Lindblom, Annika, Murabito, Joanne M., Stolk, L., Hunter, DJ, Rice, John P., Annika Lindblom, Nolte, I.M. (Ilja), Pedersen, Nancy L, Duijn, C.M. van, De Vivo, Immaculata, Loos, RJF, Feenstra, B. (Bjarke), Vivo, I. De, Nolte, Ilja M.; id_orcid, Bolla, M.K. (Manjeet), Franke, L, Völzke, H, Wright, M.J. (Margaret), Feenstra, Bjarke, Dunning, A.M. (Alison), Brauch, H., Lambrechts, Diether, Australian Ovarian Canc Study, Bojesen, SE, Mads Melbye, Hamann, U. (Ute), Wallaschofski, Henri, Paternoster, L. (Lavinia), Hottenga, JJ (Jouke Jan), Ang, W.Q., Haring, R. (Robin), Hottenga, J.J., Hartman, Catharina A., Giles, Graham G, Demerath, EW, Cornelia M. van Duijn, Kiel, Douglas P, Stöckl, D., Peterlongo, P, Nancy L. Pedersen, Neven, P, Visser, Jenny, Wolffenbuttel, BHR, Hua Zhao, Jing, Milne, RL, Perry, J.R.B. (John), Beckmann, MW, Boyd, H.A. (Heather), Thorsteinsdottir, U, Magnusson, Patrik K, Snieder, H. (Harold), Sørensen, TI, Pedersen, N.L. (Nancy L.), Jing Hua Zhao, Salomaa, V. (Veikko), Blomqvist, Carl, van Duijn, Cornelia M., Behrooz Z. Alizadeh, Australian Ovarian Cancer Study, Pers, Tune H., McArdle, W.L. (Wendy), Milne, Roger L., Thorsteinsdottir, U. (Unnur), Eriksson, J.G., Brenner, H, Kiel, Douglas, Koller, Daniel L, Easton, Douglas F., Enda M. Byrne, Nohr, Ellen A, Kiel, D.P., Atsma, Femke, Eleonora Porcu, D’adamo, A.P., Collee, Margriet, Andrulis, I.L. (Irene), Ulivi, S., de Geus, EEJ, Waldenberger, M., Snieder, Harold, Giles, G.G., Murabito, J.M., Ferreira, T., Hooning, Maartje J, Flesch Janys, Dieter, Hagen, K. (Knut), Oldehinkel, Albertine J, Garcia, ME, Tim D. Spector, Peto, J., Melbye, M, Knight, J.A. (Julia), Zhao, JH, Nolte, IM, Pharoah, Paul D. P., Stig E. Bojesen, Oostra, Ben A, Michailidou, K, Blomqvist, C, Schlessinger, David, David J. Hunter, Douglas P. Kiel, Chenevix Trench, Georgia, Stampfer, Meir, Hu, Frank, Kathryn L. Lunetta, Ingelsson, E, Cousminer, Diana L, Vollenweider, P, Pouta, A. (Anneli), Econs, Michael J., Gudbjartsson, Daniel F., Lawlor, D, Widen, E. (Elisabeth), Ang, Wei Q., Kutalik, Z. (Zoltán), Esko, T. (Tõnu), Elisabeth Widen, Coveillo, Andrea D, Hartman, Catharina A, Geller, F., Melbye, M., Johnson, Andrew D., Zhao, J., McCarthy, M.I. (Mark), Geus, E.E.J. de, Eriksson, Johan G, Boyd, Heather A, Stolk, L. (Lisette), Duijn, C.M. (Cornelia) van, Anton Culver, Hoda, Wolffenbuttel, B.H.R., Hopper, John L., Streeten, E.A. (Elizabeth), Hamann, U, Najaf Amin, Mägi, R., Cousminer, Diana L., Mihailov, Evelin, Wang, Q. (Qing), Visser, J.A. (Jenny), Bierut, LJ, Collée, JM, Ring, S, Nolte, I.M., Brenner, H. (Hermann), Cox, A. (Angela), Geller, F. (Frank), Pykäs, K. (Katri), Benitez, Javier, Serena Sanna, Storniolo, A.M. (Anna M.), Munro Peacock, Doris Stöckl, Salomaa, V., Julie E. Buring, Chasman, D.I. (Daniel), Hunter, D.J., Tõnu Esko, Teumer, A. (Alexander), Aida K. Dieffenbach, Garcia, Melissa E, Johnson, A.D., Beckmann, Matthias W, Vollenweider, P., Waeber, G. (Gérard), Fasching, P.A., Early Growth Genetics EGG Consorti, Michailidou, K., Atsma, F, Gudbjartsson, Daniel F, Wang, Q, Wallaschofski, H. (Henri), Dunning, Alison M, Porcu, E., Bergmann, S, Day, F.R. (Felix), Albrecht, E. (Eva), Palotie, Aarno, Kari Stefansson, Bolla, Manjeet K., Neven, Patrick, Ang, Wei Q, Lunetta, Kathryn L, Khaw, KT, Hottenga, J.J. (Jouke Jan), Hamann, Ute, Hu, Frank B., Albert V. Smith, Kosma, Veli-Matti, Smith, A.V., Masson, Gisli, Pharoah, Paul Dp, David P. Strachan, Mihailov, E., Nora Franceschini, Dennis, Joe, Wareham, Nicholas J, Chasman, DI, Chen, Jinhui, Sovio, U. (Ulla), Masson, G., Eriksson, JG, Ellen A. Nohr, McArdle, Patrick F, Smith, G.D., Franceschini, N., Vilmundur Gudnason, Rudolph, Anja, Radice, Paolo, Visser, Jenny A, Natalia Tšernikova, Laura J. Bierut, Pedersen, N.L., Study, KLC, Haring, Robin, Heath, AndrewC, Chang-Claude, J, Milani, Lili, Murray, A., Jarvelin, M.-R. (Marjo-Riitta), Pedersen, NL, Bjarke Feenstra, Robert Winqvist, Storniolo, Anna M., Wolffenbuttel, B.H., Geus, E.E. de, Waeber, G., Hu, FB, Pouta, A., Widen, Elisabeth, Dieffenbach, A.K. (Aida Karina), Karasik, D. (David), Guo, SQ, Franke, Lude, He, Chunyan, Perry, JR, Peacock, M, Peterlongo, P. (Paolo), Ang, W.Q. (Wei), Carl Blomqvist, Pennell, Craig E., Hall, P., Järvelin, Marjo Riitta, Heath, A., Bojesen, Stig E, Porcu, E. (Eleonora), Sørensen, Thorkild Ia, Hooning, Maartje, Mark I. McCarthy, Wright, Margaret J, Joe Dennis, Boerwinkle, E.A. (Eric), Gerard Waeber, Guo, S., Perry, John R.B., Network, GENICA, Bergmann, S., Guénel, P, Thompson, D. (Deborah), Peto, J, Sulem, Patrick, Southey, Mellissa C., Murabito, JM, Frank Geller, Gudbjartsson, DF, Teumer, Alexander, Magnusson, P.K. (Patrik), Catharina A. Hartman, Chanock, Stephen, Paul D. P. Pharoah, Julian Peto, Heath, AC, Hooning, M.J. (Maartje), Ring, S., David Schlessinger, Bandinelli, S. (Stefania), Hottenga, JJ, Zygmunt, Marek, Stampfer, MJ, Pennell, CE, Wendy L. McArdle, He, CY, Peterlongo, P., Veikko Salomaa, Porcu, Eleonora, de Geus, E.J.C., Dorret I. Boomsma, Willemsen, G.; id_orcid, Henri Wallaschofski, Postma, Dirkje S, Khaw, Kay-Tee, Montgomery, Grant W, Byrne, EM, Coveillo, Andrea D., Devilee, P, Stampfer, M., Pouta, A, Feenstra, B., Amin, N, Stefansson, Kari, Ferreira, T. (Teresa), Gasparini, Paolo, Consortium, InterAct, Spector, T.D. (Timothy), Postma, D.S., Rose, L.M., Porcu, E, Nohr, E.A., Boomsma, Dorret I., Ganna, A., McArdle, W.L., Vollenweider, Peter, He, C. (Chunyan), Alizadeh, BZ, Arto Mannermaa, Kraft, Peter, He, C, Perry, JRB, Thompson, Deborah J, Schmidt, MK (Marjanka), Reedik Mägi, Felix Day, Hofman, A. (Albert), Zhao, J.H. (Jing Hua), Flyger, H., Albert Hofman, Geller, F, Nohr, C. (Christian), Voelzke, H, D'adamo, A.P., Foroud, T., Nevanlinna, H., Ganna, Andrea, Corre, T., Gieger, Christian, Buring, Julie E, Karasik, D., Peacock, Munro, Geus, E.J.C. (Eco) de, Esko, T., Aarno Palotie, Blomqvist, C. (Carl), Kosma, VM, Oldehinkel, AJ (A.), Oldehinkel, A.J., Palotie, A. (Aarno), Graham G. Giles, Loos, RJ, Katri Pylkäs, Peter A. Fasching, Czene, K., Hottenga, Jouke Jan, Bierut, Laura J., Jaervelin, Marjo-Riitta, Chanock, S.J. (Stephen), Franke, L., Thorleifsson, Gudmar, Study, Australian Ovarian Canc, Alexander Teumer, Amin, N., Hartman, C.A., Oostra, B.A., Couper, D.J. (David), Ring, Susan, Christian Gieger, Streeten, EA, Bierut, L.J. (Laura), Geller, Frank, Albrecht, E, Chunyan He, John R. B. Perry, Andrulis, IL, Peacock, M., Perry, John Rb, McMahon, George, Sanela Kjellqvist, McArdle, P.F., Oostra, Ben, Lynda M. Rose, Visser, Jenny; id_orcid, Paolo Gasparini, Patrick Neven, Hottenga, Jouke-Jan, Spector, T.D., Mannermaa, A, Loos, R.J.F., D’adamo, Adamo Pio, Yerges-Armstrong, Laura M, Heath, A, Waeber, G, Nevanlinna, H, Loos, R.J., Kosma, Veli Matti, Gasparini, P. (Paolo), Nevanlinna, H. (Heli), Winqvist, R., Ring, S.M. (Susan), Sørensen, T.I., Wolffenbuttel, BH, Lai, Sandra, Stolk, L, Sanna, S. (Serena), Widen, E, Couper, D., Postma, DS, Crisponi, L., Tatiana Foroud, Chasman, D.I., Easton, D.F., Chang-Claude, Jenny, Wagner, E.K. (Erin K.), He, C., Radice, P, Storniolo, Anna M, Chenevix-Trench, G., Heather A. Boyd, Khaw, Kay Tee, Jinhui Chen, Adamo, P. (Pio) d', Stoeckl, D, Brenner, Hermann, Gudny Eiriksdottir, Timpson, N.J., Schmidt, MK, Paternoster, L, Michailidou, K. (Kyriaki), Ken K. Ong, Lisette Stolk, Storniolo, AM, Ridker, Paul M., Sandra Lai, Koller, D.L. (Daniel), Hottenga, J-J, Winqvist, R. (Robert), Melissa E. Garcia, Couch, Fergus J, Sorensen, Thorkild I. A., Rivadeneira Ramirez, F. (Fernando), Andrulis, Irene L, Harris, Tamara B, Elks, CE, D'adamo, Adamo Pio, Montgomery, G.W. (Grant), Amin, Najaf, Stolk, Lisette, Kutalik, Z, LifeLines Cohort Study, Storniolo, A., Ruth J. F. Loos, Sanna, S, Knight, Julia A, Eiriksdottir, Gudny, Hua Zhao, J., Wolffenbuttel, Bruce H.R., Laura M. Yerges-Armstrong, Dieffenbach, AK, Robin Haring, Crisponi, L, Dunning, A.M., Deborah J. Thompson, Tyrer, Jonathan, Elks, C.E. (Cathy), Hu, F.B., Hottenga, J.-J., Collée, J.M. (Margriet), Jenny Chang-Claude, Tyrer, J, Peter Vollenweider, Postma, Dirkje S., Ben A. Oostra, Pio d'Adamo, A., Giles, Graham G., Georgia Chenevix-Trench, Lindblom, A. (Annika), Wallaschofski, H, Murray, Anna, Zygmunt, M. (Marek), Thorleifsson, G. (Gudmar), Wallaschofski, H., Widen, E., Pylkäs, K., Boerwinkle, Eric, Mcmahon, G. (George), Esko, Toenu, Tikkanen, E., Eiriksdottir, G, Perry, John R. B., Gasparini, P., Pharoah, Paul D.P., Lunetta, Kathryn L., Lai, S, Lawlor, D.A. (Debbie), Boerwinkle, E, Uitterlinden, AG, Haring, R., Bonanni, B, Bandinelli, S., Sovio, U, Masson, G. (Gisli), Gieger, C, Tikkanen, E. (Emmi), Flyger, Henrik, Wagner, E.K., Wagner, Erin K., He, C.Y., Tamara B. Harris, Bolla, MK, Murray, A. (Anna), Unnur Thorsteinsdottir, Schlessinger, D., Qin Wang, Pennell, C.E., van Duijn, CM, Palotie, A, García-Closas, M. (Montserrat), Paul M. Ridker, Heath, Andrew C, Michailidou, Kyriaki, Ferrucci, L. (Luigi), Chasman, Daniel I, Buring, Julie, Maegi, Reedik, Martin, NG, Nolte, IM (Ilja), Bolla, M.K., Foroud, T, Oldehinkel, A.J. (Albertine), Southey, Mellissa C, ?, ?, Salomaa, V, Beckmann, M.W. (Matthias), Garcia, M. (Melissa), Zhao, Jing Hua, Melbye, M. (Mads), Pascal Guénel, Thompson, Deborah J., Guenel, P., Zwart, J-A. (John-Anker), Duijn, Cornelia, Visser, Jenny A., Ridker, Paul, Patrick F. McArdle, Kiel, Douglas P., Stöckl, D. (Doris), Dennis, J, Palotie, A., Demerath, Ellen W, Rice, J.P., Sørensen, Thorkild I. A., Lili Milani, Flesch-Janys, Dieter, Buring, J.E. (Julie), Magnusson, PK, Stöckl, D, Hooning, Maartje J., Guénel, P. (Pascal), Maartje J. Hooning, Bandinelli, Stefania, Tšernikova, N, Pennell, C.E. (Craig), Snieder, H, Chang-Claude, J. (Jenny), Bergmann, Sven, Anton-Culver, H, Kjellqvist, S. (Sanela), McArdle, P.F. (Patrick), Bergmann, S.M. (Sven), Daniel I. Chasman, Loos, R.J.F. (Ruth), Wareham, N.J. (Nick), Sørensen, Thorkild I.A., Loos, Ruth J.F., Collee, J. Margriet, Milani, L, Guo, S.Q., Gudnason, V. (Vilmundur), Hunter, David J, Tsernikova, N., De Vivo, I., Mihailov, E. (Evelin), Crisponi, Laura, Susan Ring, Yerges-Armstrong, L.M., Esko, T, Buring, JE, Peto, Julian, Rice, JP, Chasman, Daniel, Franceschini, Nora, Cousminer, D.L., Nolte, Ilja M., Easton, Douglas F, Rice, John P, Alison M. Dunning, Feenstra, B, Chenevix-Trench, G, Wang, Q., Byrne, E.M., Waldenberger, Melanie, GENICA Network, Diether Lambrechts, Alizadeh, Behrooz Z, Ferrucci, L, Oldehinkel, Albertine J., Knight, J.A., Meir J. Stampfer, van Duijn, C.M., Tikkanen, Emmi, Brenner, H., Elizabeth A. Streeten, Southey, M.C. (Mellissa C.), Peter Devilee, Uitterlinden, A.G. (André), Stampfer, Meir J, McArdle, Wendy L., Vivo, I. (Immaculata) de, Sorensen, Thorkild IA, Giles, G.G. (Graham), Ridker, PM, Couch, FJ, Luigi Ferrucci, Coviello, AD, Fasching, PA, Mägi, R, Lai, S. (Sandra), Waldenberger, M. (Melanie), Ganna, A. (Andrea), Diana L. Cousminer, Chen, JH, Nevanlinna, Heli, De Vivo, I, Ferreira, Teresa, kConFabt LifeLines Cohort Study, Gudnason, V, John L. Hopper, Consortium, I, Neven, P. (Patrick), Eva Albrecht, Devilee, Peter, Elks, Cathy E., Flesch-Janys, D., Mihailov, E, Hoda Anton-Culver, Teumer, A., Anja Rudolph, Tyrer, J., Atsma, F., Chen, J., Demerath, E.W., Wei Q. Ang, Flesch-Janys, D, Schmidt, Marjanka K, Wareham, NJ, Rose, Lynda M., Smith, Albert V., Teumer, A, Alizadeh, B.Z. (Behrooz), Streeten, E.A., McCarthy, M.I., Waeber, Gerard, Ong, Ken K., Daniel L. Koller, Corre, Tanguy, Chanock, S., Demerath, E.W. (Ellen), Lai, S., Byrne, Enda M., Couper, David, Harris, TB, Zygmunt, M., Cousminer, D.L. (Diana), Lunetta, K.L. (Kathryn), Franke, L. (Lude), Garcia, M.E., Wareham, Nicholas J., Dieter Flesch-Janys, Couch, Fergus J., Nohr, Ellen A., Schmidt, M.K., Dirkje S. Postma, Montserrat García-Closas, Fasching, Peter A., Benitez, J, Oostra, B.A. (Ben), Perry, J.R.B., Oostra, BA, Couch, F.J., Angela Cox, Dunning, Alison M., Timpson, Nicholas J., Smith, A.V. (Davey), Jonathan Tyrer, Foroud, T. (Tatiana), Hofman, Albert, Zhao, J.H., Kamila Czene, Mannermaa, A., Eric Boerwinkle, Pylkäs, K, Rudolph, A., Hiltrud Brauch, André G. Uitterlinden, Day, F, Winqvist, R, Patrick Sulem, Peto, J. (Julian), Chang-Claude, J., Hamann, U., Chen, J, Koller, Daniel L., Voelzke, Henry, Stoeckl, Doris, Crisponi, L. (Laura), Lambrechts, D. (Diether), Sørensen, Thorkild I A, Dieffenbach, A.K., Strachan, DP, Hartman, CA, de Geus, Eco Ej, Tanguy Corre, Adamo Pio D’adamo, Karasik, D, Debbie Lawlor, Boyd, H.A., Grant W. Montgomery, Neven, P., Stefania Bandinelli, Spector, TD, Devilee, P. (Peter), Johnson, Andrew D, Brauch, H. (Hiltrud), Collée, J Margriet, Kiel, D.P. (Douglas P.), Hall, P, Benitez, J., Peacock, M. (Munro), Waldenberger, M, Sulem, P., Hu, F.B. (Frank), Rice, J.P. (John), Ferrucci, L., Anton-Culver, Hoda, Järvelin, M-R, Jouke-Jan Hottenga, Peter Kraft, Gudnason, V., Oldehinkel, AJ, Henry Völzke, Antonietta Robino, Econs, Michael J, Henrik Flyger, Martin, N.G., Guénel, Pascal, Kraft, Phillip, Rudolph, A, Magnusson, P.K., Sorensen, T.I.A., Robino, Antonietta, Teresa Ferreira, Strachan, David P, Tikkanen, E, Andrea Ganna, Thorkild I. A. Sørensen, Hunter, David, Ilja M. Nolte, Martin, Nicholas G., Wang, Qin, Albertine J. Oldehinkel, Hu, Frank B, Hofman, Bert, Andrulis, Irene L., Bonnani, B. (Bernardo), Consorti, EGGEGG, Kraft, P., Andrea D. Coviello, Boyd, HA, Patrik K. Magnusson, Heath, A.C. (Andrew), Ong, K.K. (Ken K.), Eriksson, Johan G., Stampfer, M.J., Eco E. J. de Geus, Erik Ingelsson, Ferrucci, Luigi, Buring, Julie E., Masson, G, Bernardo Bonanni, Julia A. Knight, Boomsma, D.I. (Dorret), Spector, Tim D., Coviello, Andrea D, Dunning, AM, Pers, T.H., Czene, K, Buring, J.E., Easton, DF, Wright, Margaret J., Snieder, H., Ulivi, Sheila, Haring, R, Tyrer, J.P. (Jonathan), Jenny A. Visser, Kay-Tee Khaw, Uitterlinden, André, Pouta, Anneli, Kraft, P, Bojesen, S.E. (Stig), Khaw, K-T, Immaculata De Vivo, Mägi, R. (Reedik), Maegi, R, Khaw, K.-T., Hopper, J.L. (John)   +999 more
core   +1 more source

Cis -acting expression quantitative trait loci in mice [PDF]

Genome Research, 2005
We previously reported the analysis of genome-wide expression profiles and various diabetes-related traits in a segregating cross between inbred mouse strains C57BL/6J (B6) and DBA/2J (DBA). By considering transcript levels as quantitative traits, we identified several thousand expression quantitative trait loci (eQTL) with LOD ...
Doss, S, Schadt, E E, Drake, T A, Lusis, Aldons J   +3 more
openaire   +3 more sources

Multiple sclerosis risk variants regulate gene expression in innate and adaptive immune cells

Life Science Alliance, 2020
This comprehensive study identifies multiple sclerosis risk expression quantitative trait loci in purified immune cell types. At least 200 single-nucleotide polymorphisms (SNPs) are associated with multiple sclerosis (MS) risk.
Melissa M Gresle, Margaret A Jordan, Jim Stankovich, Tim Spelman, Laura J Johnson, Louise Laverick, Alison Hamlett, Letitia D Smith, Vilija G Jokubaitis, Josephine Baker, Jodi Haartsen, Bruce Taylor, Jac Charlesworth, Melanie Bahlo, Terence P Speed, Matthew A Brown, Judith Field, Alan G Baxter, Helmut Butzkueven   +18 more
doaj   +1 more source

Expression quantitative trait loci (eQTL) mapping in Puerto Rican children. [PDF]

PLoS ONE, 2015
Expression quantitative trait loci (eQTL) have been identified using tissue or cell samples from diverse human populations, thus enhancing our understanding of regulation of gene expression.
Wei Chen, John M Brehm, Jerome Lin, Ting Wang, Erick Forno, Edna Acosta-Pérez, Nadia Boutaoui, Glorisa Canino, Juan C Celedón   +8 more
doaj   +1 more source

GSTCD and INTS12 Regulation and Expression in the Human Lung [PDF]

, 2013
Genome-Wide Association Study (GWAS) meta-analyses have identified a strong association signal for lung function, which maps to a region on 4q24 containing two oppositely transcribed genes: glutathione S-transferase, C-terminal domain containing (GSTCD ...
Swan, Caroline, Erik Melén (276082), Ma'en Obeidat, Hao Ke, S. Miller (3494552), Nelson, CP, I. Sayers (3494558), Henry, Amanda P., Probert, Kelly, C. Swan (7390268), Sayers, Ian, Miller Suzanne, K. Probert (7667498), Hodge, E, Maxime Lamontagne (116448), Ma’en Obeidat (460144), Ushey Kevin, Hao, Ke, Dirkje S Postma, Kevin Ushey (181019), Tobin, MD, Wain, LV, Amanda P. Henry (460148), Dirkje S. Postma (101740), Y. Bossé (7628753), Lamontagne, M, Miller, Suzanne, Obeidat Ma’en, Wain, Louise V., Melén Erik, María Soler Artigas (7603997), Caroline Swan (37264), Ceri E. Stewart (460151), Obeidat, Ma'en, Stewart, CE, E. Melén (3494549), Soler Artigas, María, Bossé, Y, Caroline Swan, Kelly Probert (460146), Nelson, Carl P., Nelson Carl P., Stewart Ceri E., Postma, Dirkje S., Lamontagne Maxime, Probert, K, Ceri E Stewart, Hao, K, Carl P Nelson, Hall Ian P., Erik Melén, Ke Hao, Postma Dirkje S., Artigas, Maria Soler, K. Hao (7628756), Billington Charlotte K., Kevin Ushey, Charlotte K. Billington (460147), D. S. Postma (3809164), M. Obeidat (7628729), María Soler Artigas (110124), Louise V. Wain (7588511), Martin D Tobin, Carl P. Nelson (460150), Ushey, Kevin, Ian Sayers, C. P. Nelson (7591670), Tobin Martin D., Ian P. Hall (110307), Hodge, Emily, Ian P Hall, Maxime Lamontagne, Louise V Wain, C. K. Billington (7667501), Emily Hodge (460149), Ke Hao (50181), Wain Louise V., Bossé Yohan, Sayers, I, Ushey, K, Hall, IP, Louise V. Wain (110260), Amanda P Henry, Emily Hodge, Artigas, MS, C. E. Stewart (7627559), Melen, Erik, E. Hodge (7643807), Billington, Charlotte K., Suzanne Miller, Obeidat, Ma�en, Henry Amanda P., Soler Artigas, Mar�a, Hodge Emily, Probert Kelly, Obeidat, M, Lamontagne, Maxime, Billington, CK, K. Ushey (7667507), Boss�, Yohan, Melén, E, A. P. Henry (7667504), Sayers Ian, Swan, C, Kelly Probert, Stewart, Ceri E., Obeidat, Ma’en, Ian Sayers (37266), Martin D. Tobin (7581161), Artigas María Soler, Henry, AP, Postma, DS, Yohan Bossé (69571), Hall, Ian P., Tobin, Martin D., Suzanne Miller (460145), Yohan Bossé, M. Lamontagne (7667510), Swan Caroline, Martin D. Tobin (110311), Mel�n, Erik, Miller, S, Charlotte K Billington, María Soler Artigas, Bosse, Yohan, I. P. Hall (7628774)   +125 more
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Single cell expression quantitative trait loci and complex traits [PDF]

Genome Medicine, 2013
The recently developed ability to quantify mRNA abundance and noise in single cells has allowed the effect of heritable variations on gene function to be re-evaluated. A recent study has shown that major sources of variation are masked when gene expression is averaged over many cells.
openaire   +3 more sources

Cross-Talk of Expression Quantitative Trait Loci Within 2 Interacting Blood Pressure Quantitative Trait Loci [PDF]

Hypertension, 2007
Genetic dissection of the S rat genome has provided strong evidence for the presence of 2 interacting blood pressure quantitative trait loci (QTLs), termed QTL1 and QTL2, on rat chromosome 5. However, the identities of the underlying interacting genetic factors remain unknown.
Norman H, Lee, Brian J, Haas, Noah E, Letwin, Bryan C, Frank, Truong V, Luu, Qiang, Sun, Carrie D, House, Shane, Yerga-Woolwine, Phyllis, Farms, Ezhilarasi, Manickavasagam, Bina, Joe   +10 more
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Unraveling the Regulatory Mechanisms Underlying Tissue-Dependent Genetic Variation of Gene Expression [PDF]

, 2012
It is known that genetic variants can affect gene expression, but it is not yet completely clear through what mechanisms genetic variation mediate this expression.
Harry J M Groen, Veldink, Jan,, Meerman, Gerard J. te,, Groen, Harry JM, Westra, Harm-Jan,, Ophoff, Roel A.,, Wolfs, Marcel G.M.,, Snieder, Harold; id_orcid, Fehrmann, Rudolf S.N.,, Fu, J, Harry J. M. Groen (101726), Groen, H.J., Fu, Jingyuan, Westra, Harm Jan, Wolfs Marcel G. M., Patrick Deelen, Westra, Harm Jan; id_orcid, Wim A Buurman, van Heel David, Weersma, RK, Groen, Harry J.M.,, Marcel G M Wolfs, Marten H. Hofker (102396), Buurman Wim A., Patrick Deelen (187548), Jansen, R.C., Fehrmann, R.S., Weersma, Rinse K; id_orcid, Harm-Jan Westra, Jansen, Ritsert C, Wijmenga, Cisca, Meerman, GJT, Cisca Wijmenga, Gerard J Te Meerman, Franke, L, Fehrmann, RSN, Rensen, SSM, Wolfs, MGM, Jingyuan Fu (102399), Weersma, Rinse K.,, Rinse K. Weersma (131692), van den Berg, Leonard H, Harold Snieder (103613), Rensen, Sander S.M.,, Fu, Jingyuan,, Fehrmann, Rudolf S N, Rensen, Sander S M, van den Berg, L.H., Sander S. M. Rensen (187559), van den Berg Leonard H., Snieder Harold, Heel, David van,, Snieder, Harold,, Leonard H van den Berg, te Meerman, G.J., te Meerman Gerard J., Ritsert C Jansen, Wolfs, M.G., Deelen, Patrick, Snieder, H., Fu Jingyuan, Deelen, P., Cisca Wijmenga (32954), Weersma, R.K., Wijmenga, Cisca,, Roel A. Ophoff (155472), Wim A. Buurman (162734), Fu, Jingyuan; id_orcid, Franke, L., Groen, Hendricus, Ophoff, RA, Wolfs, Marcel GM, Wolfs, Marcel G M, Hofker Marten H., Buurman, WA, Leonard H. van den Berg (119440), van Heel, D., Westra, H-J, Hofker, MH, Lude Franke (102406), Buurman, W.A., Jan Veldink, Groen Harry J. M., Wijmenga, C., Wijmenga Cisca, Veldink, Jan, Meerman, Gerard J te, Lude Franke, Weersma, Rinse K, Jansen, Ritsert C.,, Sander S M Rensen, Wijmenga, C, Harm-Jan Westra (102374), Westra, H.J., Veldink, J., van den Berg, LH, Snieder, Harold, David van Heel (187571), Harold Snieder, David van Heel, Westra, Harm-Jan, Rudolf S. N. Fehrmann (87558), Westra Harm-Jan, Ophoff, Roel A, Deelen Patrick, Berg, Leonard H. van den,, Rensen Sander S. M., Fehrmann, Rudolf SN, Wijmenga, Cisca; id_orcid, Roel A Ophoff, Franke, Lude, Buurman, Wim A.,, Rensen, S.S.M.; id_orcid, Groen, HJM, Ritsert C. Jansen (32125), Deelen, Patrick,, van Heel, David, Rensen, Sander SM, Franke, Lude,, Rensen, S.S.M., Weersma Rinse K., Hofker, Marten H.,, Fehrmann Rudolf S. N., Franke Lude, Jan Veldink (187567), Hofker, M.H., van Heel, D, Snieder, H, Rudolf S N Fehrmann, Buurman, Wim A, Hofker, Marten H, Deelen, P, Marten H Hofker, Veldink Jan, Jingyuan Fu, Veldink, J, Rinse K Weersma, Marcel G. M. Wolfs (187544), Jansen Ritsert C., Ophoff, R.A., Jansen, RC, Gerard J. te Meerman (87570), te Meerman, Gerhardus, Ophoff Roel A., Groen, Hendricus; id_orcid, Fu, J.   +145 more
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Interpreting Functional Impact of Genetic Variations by Network QTL for Genotype–Phenotype Association Study

Frontiers in Cell and Developmental Biology, 2022
An enormous challenge in the post-genome era is to annotate and resolve the consequences of genetic variation on diverse phenotypes. The genome-wide association study (GWAS) is a well-known method to identify potential genetic loci for complex traits ...
Kai Yuan, Tao Zeng, Tao Zeng, Tao Zeng, Luonan Chen, Luonan Chen, Luonan Chen, Luonan Chen   +7 more
doaj   +1 more source