Results 11 to 20 of about 134,736 (276)

Expression quantitative trait loci analysis in plants [PDF]

Plant Biotechnology Journal, 2010
An expression Quantitative Trait Locus or eQTL is a chromosomal region that accounts for a proportion of the variation in abundance of a mRNA transcript observed between individuals in a genetic mapping population.
Chen, Xinwei, Druka, Arnis, Jiang, Ning, Kearsey, Mike, Luo, Zewei, Potokina, Elena, Waugh, Robbie   +6 more
core   +8 more sources

Expression quantitative trait loci: present and future [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2013
The last few years have seen the development of large efforts for the analysis of genome function, especially in the context of genome variation. One of the most prominent directions has been the extensive set of studies on expression quantitative trait loci (eQTLs), namely, the discovery of genetic variants that explain variation in gene expression ...
Nica, Alexandra, Dermitzakis, Emmanouil
openaire   +5 more sources

Heritability and tissue specificity of expression quantitative trait loci. [PDF]

PLoS Genetics, 2006
Variation in gene expression is heritable and has been mapped to the genome in humans and model organisms as expression quantitative trait loci (eQTLs). We applied integrated genome-wide expression profiling and linkage analysis to the regulation of gene
Enrico Petretto, Jonathan Mangion, Nicholas J Dickens, Stuart A Cook, Mande K Kumaran, Han Lu, Judith Fischer, Henrike Maatz, Vladimir Kren, Michal Pravenec, Norbert Hubner, Timothy J Aitman   +11 more
doaj   +6 more sources

Population differences in transcript-regulator expression quantitative trait loci.

PLoS ONE, 2012
Gene expression quantitative trait loci (eQTL) are useful for identifying single nucleotide polymorphisms (SNPs) associated with diseases. At times, a genetic variant may be associated with a master regulator involved in the manifestation of a disease ...
Pierre R Bushel, Ray McGovern, Liwen Liu, Oliver Hofmann, Ahsan Huda, Jun Lu, Winston Hide, Xihong Lin   +7 more
doaj   +4 more sources

Genome-wide identification of microRNA expression quantitative trait loci [PDF]

Nature Communications, 2015
Identification of microRNA expression quantitative trait loci (miR-eQTL) can yield insights into regulatory mechanisms of microRNA transcription, and can help elucidate the role of microRNA as mediators of complex traits. Here we present a miR-eQTL mapping study of whole blood from 5,239 individuals, and identify 5,269 cis-miR-eQTLs for 76 mature ...
Huan, Tianxiao, Rong, Jian, Liu, Chunyu, Zhang, Xiaoling, Tanriverdi, Kahraman, Joehanes, Roby, Chen, Brian H., Murabito, Joanne M., Yao, Chen, Courchesne, Paul, Munson, Peter J., O’Donnell, Christopher J., Cox, Nancy, Johnson, Andrew D., Larson, Martin G., Levy, Daniel, Freedman, Jane E.   +16 more
openaire   +5 more sources

Common Expression Quantitative Trait Loci Shared by Histone Genes [PDF]

International Journal of Genomics, 2017
A genome-wide association study (GWAS) was conducted to examine expression quantitative trait loci (eQTLs) for histone genes. We examined common eQTLs for multiple histone genes in 373 European lymphoblastoid cell lines (LCLs).
Hanseol Kim, Yujin Suh, Chaeyoung Lee
doaj   +3 more sources

Expression quantitative trait loci (eQTL) mapping in Puerto Rican children. [PDF]

PLoS ONE, 2015
Expression quantitative trait loci (eQTL) have been identified using tissue or cell samples from diverse human populations, thus enhancing our understanding of regulation of gene expression.
Wei Chen, John M Brehm, Jerome Lin, Ting Wang, Erick Forno, Edna Acosta-Pérez, Nadia Boutaoui, Glorisa Canino, Juan C Celedón   +8 more
doaj   +4 more sources

Genome-wide expression quantitative trait loci (eQTL) analysis in maize [PDF]

BMC Genomics, 2011
Background Expression QTL analyses have shed light on transcriptional regulation in numerous species of plants, animals, and yeasts. These microarray-based analyses identify regulators of gene expression as either cis-acting factors that regulate ...
Beatty Mary, Luck Stanley, Holloway Beth, Rafalski J-Antoni, Li Bailin   +4 more
doaj   +3 more sources

Genome-Wide Expression Quantitative Trait Loci Analysis Using Mixed Models [PDF]

Frontiers in Genetics, 2018
Expression quantitative trait loci (eQTLs) are important for understanding the genetic basis of cellular activities and complex phenotypes. Genome-wide eQTL analyses can be effectively conducted by employing a mixed model. The mixed model includes random
Chaeyoung Lee
doaj   +3 more sources

Modeling expression quantitative trait loci in data combining ethnic populations [PDF]

BMC Bioinformatics, 2010
Background Combining data from different ethnic populations in a study can increase efficacy of methods designed to identify expression quantitative trait loci (eQTL) compared to analyzing each population independently.
Hsieh Ai-Ru, Lian Ie-Bin, Hsiao Ching-Lin, Fann Cathy SJ   +3 more
doaj   +4 more sources