Results 81 to 90 of about 2,321,627 (280)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
CE-Prompt: enhance prompt expression stability by multiple understanding [PDF]
PeerJ Computer ScienceIn this article, we propose CE-Prompt, an enhanced version of Prompt-Tuning designed to address issues such as the instability of random initialization and inefficiencies caused by long text in pre-trained large language models (LLMs).
Wujian Yang +3 more
doaj +2 more sources
Tristetraprolin Down-Regulation Contributes to Persistent TNF-Alpha Expression Induced by Cigarette Smoke Extract through a Post-Transcriptional Mechanism. [PDF]
PLoS ONE, 2016 Tumor necrosis factor-alpha (TNF-α) is a potent pro-inflammatory mediator and its expression is up-regulated in chronic obstructive pulmonary disease (COPD).
Xue-Ke Zhao +20 more
doaj +1 more source
Metabolite-dependent regulation of gene expression in trypanosoma brucei [PDF]
, 2013 Mechanisms regulating gene expression in trypanosomatid protozoa differ significantly from those in other eukaryotes. Transcription of the genome appears to be more or less constitutive with the polyadenylation and trans-splicing of large polycistronic ...
Archer +34 more
core +1 more source
BMP‐2 decreases Mash1 stability by increasing Id1 expression [PDF]
The EMBO Journal, 2004 In neural development, bone morphogenetic proteins (BMPs) restrict neuronal differentiation, thereby promoting the maintenance of progenitor cells or even inducing astrocytogenesis. We report that exposure of neuroendocrine lung carcinoma cells to BMP-2 leads to a rapid decline in steady-state levels of Mash1 protein and some neuron-specific markers ...
Francesc, Viñals +5 more
openaire +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Evaluation of reference genes for gene expression studies in pig muscle tissue by real-time PCR
Czech Journal of Animal Science, 2011 The selection of reference genes is essential for gene expression studies when using a real-time quantitative polymerase chain reaction (PCR). Reference gene selection should be performed for each experiment because the gene expression level may be ...
M. Nesvadbová, A. Knoll
doaj +1 more source
PLoS ONE, 2021 Accurate and reliable relative gene expression analysis via the Reverse Transcription-quantitative Real Time PCR (RT-qPCR) method strongly depends on employing several stable reference genes as normalizers.
Gilar Gorji-Bahri +2 more
doaj +1 more source
General model of a cascade of reactions with time delays: global stability analysis
, 2014 The problem considered in this paper consists of a cascade of reactions with discrete as well as distributed delays, which arose in the context of Hes1 gene expression.
Bodnar, Marek
core +1 more source
Stability of metabolic networks via Linear-in-Flux-Expressions
Networks & Heterogeneous Media, 2019 30 pages, 6 ...
Merrill, Nathaniel +6 more
openaire +6 more sources