Results 141 to 150 of about 412,727 (336)
Malaria infected red blood cells release small regulatory RNAs through extracellular vesicles [PDF]
, 2018 Kehinde Adebayo Babatunde +9 more
openalex +1 more source
EV Fingerprinting: Resolving extracellular vesicle heterogeneity using multi-parametric flow cytometry [PDF]
, 2022 Ariana von Lersner +12 more
openalex +1 more source
Targeted delivery of lysosomal enzymes to the endocytic compartment in human cells using engineered extracellular vesicles. [PDF]
, 2019 Targeted delivery of lysosomal enzymes to the endocytic compartment of human cells represents a transformative technology for treating a large family of lysosomal storage diseases (LSDs).
Brown, Annie +4 more
core +1 more source
The Presence of GC-C in Extracellular Vesicles Secreted by Colorectal Cancer Cells [PDF]
, 2020 Background: Guanylyl Cyclase C (GC-C) is a membrane-bound protein found on intestinal epithelial cells involved in the activation of CFTR. This protein has previously been involved in the development of colorectal cancer. Extracellular vesicles (EVs) are
Martinez, Alexandre, Snook, Adam E.
core +1 more source
Cell Calcification Models and Their Implications for Medicine and Biomaterial Research
Advanced Healthcare Materials, EarlyView.Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter +5 more
wiley +1 more source
Frontiers in MicrobiologyBackgroundThe spread of antimicrobial resistance (AMR) poses significant threats to human health. In 2024, the World Health Organization (WHO) classified carbapenem-resistant Enterobacteriaceae (CRE) as a critical-priority pathogen and carbapenem ...
Yajuan Guan +9 more
doaj +1 more source
Immunogenicity of Extracellular Vesicles
Advanced MaterialsAbstractExtracellular vesicles (EVs) are promising next‐generation therapeutics and drug delivery systems due to demonstrated safety and efficacy in preclinical models and early‐stage clinical trials. There is an urgent need to address the immunogenicity of EVs (beyond the apparent lack of immunotoxicity) to advance clinical development.
Yutian Xia +3 more
openaire +2 more sources
A Human Neural Tube Model Using 4D Self‐Folding Smart Scaffolds
Advanced Healthcare Materials, EarlyView.Induced pluripotent stem cells (iPSCs) exhibit features comparable to the inner cell mass of the human embryo. iPSCs are applied to a novel self‐folding 4D‐Neural Tube (4D‐NT) structure that mimics the neurulation process. This 4D‐NT model recapitulates early events of human neural development and represents a platform to explore neurodevelopmental ...
Claudia Dell'Amico +8 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This study introduces an innovative approach to treating intervertebral disc degeneration using ultrasound‐triggered in situ hydrogel formation. Proof‐of‐concept experiments using optimized biomaterial and ultrasound parameters demonstrate partial restoration of biomechanical function and successful integration into degenerated disc tissue, offering a ...
Veerle A. Brans +11 more
wiley +1 more source