Results 141 to 150 of about 977,542 (369)
Molecular fingerprinting of biological nanoparticles with a label-free optofluidic platform [PDF]
arXiv, 2023 Label-free detecting multiple analytes in a high-throughput fashion has been one of the long-sought goals in biosensing applications. Yet, for all-optical approaches, interfacing state-of-the-art label-free techniques with microfluidics tools that can process small volumes of sample with high throughput, and with surface chemistry that grants analyte ...
arxiv
New Technologies for Analysis of Extracellular Vesicles.
Chemical Reviews, 2018 Extracellular vesicles (EVs) are diverse, nanoscale membrane vesicles actively released by cells. Similar-sized vesicles can be further classified (e.g., exosomes, microvesicles) based on their biogenesis, size, and biophysical properties.
Huilin Shao +5 more
semanticscholar +1 more source
Clinical significance of stratifying prostate cancer patients through specific circulating genes
Molecular Oncology, EarlyView.We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian +12 more
wiley +1 more source
Lipids in Health and DiseaseMalignant tumors represent a significant worldwide health challenge, with elevated morbidity and mortality rates necessitating enhanced early identification and individualized treatment.
Weichu Tan, Yitong Zhu, Siting Chen
doaj +1 more source
Quantitative Analysis of Cargo Density in Single-extracellular Vesicles by Imaging
Bio-Protocol, 2018 Function of extracellular vesicles such as exosomes and microvesicles is determined by their wide ranges of cargoes inside them. Even in the pure exosomes or microvesicles the cargo contents are very heterogeneous. To understand this heterogeneous nature
Taketoshi Kajimoto, Shun-ichi Nakamura
doaj +1 more source
Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source
ACS Omega, 2020 Extracellular vesicles (EVs), including exosomes and microvesicles (
Getnet Midekessa +11 more
semanticscholar +1 more source
The roles and applications of extracellular vesicles in cancer
Molecular Oncology, EarlyView.Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley +1 more source
Sonication is a suitable method for loading nanobody into glioblastoma small extracellular vesicles
Heliyon, 2023 Glioblastoma is one of the deadliest cancers, therefore novel efficient therapeutic approaches are urgently required. One of such are nanobodies, prospective nano-sized bio-drugs with advantageous characteristics.
Sara Colja +4 more
doaj
Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
wiley +1 more source