Results 51 to 60 of about 210,770 (319)
Precise nanosizing with high dynamic range holography [PDF]
, 2020 Optical sensing is one of the key-enablers of modern diagnostics. Especially label-free imaging modalities hold great promise as they eliminate labeling procedures prior to analysis. However, scattering signals of nanometric particles scale with their volume-square.
arxiv +1 more source
Metalloproteinases in extracellular vesicles
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2017 Extracellular vesicles (EVs) have emerged as pivotal mediators of intercellular communications in local and distant microenvironments under patho/physiological conditions. EVs contain bioactive materials such as proteins, RNA transcripts, microRNAs and even DNAs, and recent work on their protein profiles has revealed the existence of metalloproteinases
Masayuki Shimoda +2 more
openaire +3 more sources
Extracellular Vesicles—Connecting Kingdoms [PDF]
International Journal of Molecular Sciences, 2019 It is known that extracellular vesicles (EVs) are shed from cells of almost every type of cell or organism, showing their ubiquity in all empires of life. EVs are defined as naturally released particles from cells, delimited by a lipid bilayer, and cannot replicate. These nano- to micrometer scaled spheres shuttle a set of bioactive molecules.
Eric Woith +2 more
openaire +3 more sources
Frontiers in Neurology, 2020 Extracellular vesicles (EVs) are involved in the development and progression of neurodegenerative diseases, including Alzheimer's and Parkinson's disease.
Ricardo Quiroz-Baez +2 more
doaj +1 more source
Modelling cellular spreading and emergence of motility in the presence of curved membrane proteins and active cytoskeleton forces [PDF]
arXiv, 2021 Eukaryotic cells adhere to extracellular matrix during the normal development of the organism, forming static adhesion as well as during cell motility. We study this process by considering a simplified coarse-grained model of a vesicle that has uniform adhesion energy with a flat substrate, mobile curved membrane proteins and active forces.
arxiv
Therapeutic Potential of Extracellular Vesicles [PDF]
Frontiers in Immunology, 2014 Extracellular vesicles (EV) have emerged as important mediators of intercellular communication. By their origin, we can find vesicles derived from plasma membrane such as microvesicles, ectosomes, and membrane particles or exosomes, which originate in the endosomal membrane compartment.
Merino, Ana +3 more
openaire +4 more sources
Extracellular vesicle signalling in atherosclerosis [PDF]
Cellular Signalling, 2020 Atherosclerosis is a major cardiovascular disease and in 2016, the World Health Organisation (WHO) estimated 17.5 million global deaths, corresponding to 31% of all global deaths, were driven by inflammation and deposition of lipids into the arterial wall.
Charla, Eleni +3 more
openaire +3 more sources
The End-to-End Molecular Communication Model of Extracellular Vesicle-based Drug Delivery [PDF]
arXiv, 2022 A closer look at nature has recently brought more interest in exploring and utilizing intra-body communication networks composed of cells as intrinsic, perfectly biocompatible infrastructures to deliver therapeutics. Naturally occurring cell-to-cell communication systems are being manipulated to release, navigate, and take up soluble cell-derived ...
arxiv
Reproducibility of extracellular vesicle research
European Journal of Cell Biology, 2022 Journal article: "Reproducibility of extracellular vesicle research"
Nieuwland, Rienk +3 more
openaire +5 more sources
Frontiers in Cellular NeuroscienceParkinson’s disease is a pathology with a wide range of in vivo and in vitro models available. Among these, the SH-SY5Y neuroblastoma cell line is one of the most employed.
Angel Carvajal-Oliveros +3 more
doaj +1 more source