Results 81 to 90 of about 247,554 (291)

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source

An aggregation-induced emission-active lysosome hijacker: Sabotaging lysosomes to boost photodynamic therapy efficacy and conquer tumor therapeutic resistance

Materials Today Bio
Therapeutic resistance is a major challenge in clinical cancer theranostics, often leading to treatment failure and increased patient mortality. Breaking this therapeutic deadlock, enhancing the efficacy of clinical treatments, and ultimately improving ...
Hang Zou, Pingping Wang, Zhihao Bai, Liping Liu, Jingtong Wang, Yanfang Cheng, Bairong He, Zujin Zhao, Lei Zheng   +8 more
doaj   +1 more source

Near‐Infrared Organic Photovoltaic Electrodes for Subretinal Neurostimulation

Advanced Functional Materials, EarlyView.
Organic photovoltaic electrodes based on the D18:Y6 blend enable precise and light‐controlled activation of retinal ganglion cells in a degenerating retina. NIR Light‐driven activation of retinal ganglion cells, tunable stimulation parameters, and biocompatibility with human retinal organoids highlight their potential for next‐generation prosthetics ...
Andrea Corna, Katarina Gugujonovic, Manuela Schiek, Alessandro Bellapianta, Paul Werginz, Amelie Ziller, Markus Clark Scharber, Ahmad Salti, Matthias Bolz, Mihai Irimia‐Vladu, Günther Zeck   +10 more
wiley   +1 more source

Fibrinogen on extracellular vesicles derived from polyhexamethylene guanidine phosphate-exposed mice induces inflammatory effects via integrin β

, 2023
Jun Woo Kim, Mi Ho Jeong, Hyeong Tae Yu, Yong Joo Park, Hyung Sik Kim, Kyu Hyuck Chung   +5 more
openalex   +1 more source

Electrochemically Driven Dissipative Growth of Affinity Hydrogels for Bioresponsive Interfaces

Advanced Functional Materials, EarlyView.
Voltage pulses drive the growth and reinforcement of hydrogel films under dissipative conditions. This biocompatible strategy enables efficient integration of affinity ligands into the hydrogel matrix, enhancing the selective capture of growth factors and allowing precise temporal control over their release, making them well‐suited as adaptive ...
Roberto Baretta, Marco Frasconi
wiley   +1 more source

Bovine PMN responses to extracellular vesicles released by Besnoitia besnoiti tachyzoites and B. besnoiti-infected host cells

Frontiers in Immunology
Bovine besnoitiosis is a re-emerging cattle disease caused by the apicomplexan parasite Besnoitia besnoiti, which severely affects individual animal welfare and profitability in cattle industry. We recently showed that B.
Gabriel Espinosa, Constanza Salinas-Varas, Lisbeth Rojas-Barón, Christian Preußer, Elke Pogge von Strandmann, Ulrich Gärtner, Iván Conejeros, Carlos Hermosilla, Anja Taubert   +8 more
doaj   +1 more source

Alterations in circulating extracellular vesicles underlie social stress‐induced behaviors in mice [PDF]

, 2021
Shinji Sakamoto, Dania Mallah, Destynie Medeiros, Eisuke Dohi, Takashi Imai, Indigo V.L. Rose, Ken Matoba, Xiaolei Zhu, Atsushi Kamiya, Shin‐ichi Kano   +9 more
openalex   +1 more source

MPI‐Guided Photothermal Therapy of Prostate Cancer Using Stem Cell Delivery of Magnetotheranostic Nanoflowers

Advanced Functional Materials, EarlyView.
Tumor‐tropic human mesenchymal stem cells (hMSCs) were used as delivery vehicles for magnetotheranostic gold–iron oxide nanoflowers. Magnetic particle imaging of the iron component demonstrated widespread intratumoral distribution and sustained retention in contrast to injection of naked nanoflowers.
Behnaz Ghaemi, Ana Rosu, Shreyas Kuddannaya, Gautier Laurent, Rana Bazzi, Stéphane Roux, Ali Shakeri‐Zadeh, Jeff W. M. Bulte   +7 more
wiley   +1 more source

Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles

Advanced Functional Materials, EarlyView.
Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati, Yoann Lalatonne, Cédric Chauvierre   +2 more
wiley   +1 more source

Mesenchymal stem cell‐derived extracellular vesicles in treatment against renal fibrosis [PDF]

, 2023
Jiantao Wang, Jianxin Cui, Shengqiang Yu, Shujie Xia   +3 more
openalex   +1 more source