Extrasynaptic GABAA receptors in the crosshairs of hormones and ethanol [PDF]
Neurochemistry International, 2008 Gamma-aminobutyric acid (GABA) is the main chemical inhibitory neurotransmitter in the brain. In the central nervous system (CNS) it acts on two distinct types of receptor: an ion channel, i.e., an "ionotropic" receptor permeable to Cl- and HCO3- (GABAA receptors) and a G-protein coupled "metabotropic" receptor that is linked to various effector ...
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Sharing vesicles between central presynaptic terminals: implications for synaptic function
Frontiers in Synaptic Neuroscience, 2010 Presynaptic terminals in hippocampal neurons house functionally distinct vesicle pools, the size, structure and biochemical features of which are major determinants of presynaptic strength and performance.
Kevin Staras, Tiago Branco, Tiago Branco
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Acetylcholine receptor-like molecules are found in both synaptic and extrasynaptic clusters on the surface of neurons in the frog cardiac ganglion [PDF]
, 1989 PB Sargent, DZ Pang
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Prolonged and Extrasynaptic Excitatory Action of Dopamine Mediated by D1 Receptors in the Rat StriatumIn Vivo [PDF]
, 1997 François Gonon
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Astrocytic modulation of the synaptic and the extrasynaptic space
, 2023 Neuron-astrocyte interactions are now recognized as essential to brain functioning and information processing. They occur at multiple levels, at different cellular locations, and upon different physiological states. Hence, the general aim of this thesis was to unravel structural and molecular interactions of astrocytes with neurons that contribute to ...
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Modulating anxiety with extrasynaptic inhibition
, 2014 Traumatic experiences and stress can lead to complex behavioral adaptations, including increased levels of anxiety and fear generalization. The neuronal mechanisms underlying such maladaptive behavioral changes are, however, poorly understood. Numerous studies have indicated that, in both animals and humans, the amygdala is a key brain structure ...
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Single Ethanol Withdrawal Regulates Extrasynaptic δ-GABAA Receptors Via PKCδ Activation
Frontiers in Molecular Neuroscience, 2018 Alcohol (ethanol, EtOH) is one of the most widely abused drugs with profound effects on brain function and behavior. GABAA receptors (GABAARs) are one of the major targets for EtOH in the brain.
Juan Chen +9 more
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Increased Exon 5 Expression Alters Extrasynaptic NMDA Receptors in Cerebellar Neurons [PDF]
, 2000 Kate Prybylowski +3 more
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Neurobiology of Disease, 2023 Evidence suggests that inhibition of α/β hydrolase-domain containing 6 (ABHD6) reduces seizures; however, the molecular mechanism of this therapeutic response remains unknown.
Ruth Westenbroek +3 more
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Extrasynaptic Release of Dopamine in a Retinal Neuron [PDF]
, 2001 Michelino Puopolo +4 more
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