Results 1 to 10 of about 600,014 (146)
pH-regulated nuclear F-actin assembly during ferroptosis [PDF]
Frontiers in Cell and Developmental BiologyIntroductionFerroptosis is an iron-dependent form of programmed cell death driven by lipid peroxidation and loss of membrane integrity, frequently modeled with small molecules such as RSL3 that inhibit Glutathione Peroxidase 4 (GPX4).
Menghao Qiao +10 more
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Cryo-EM structure revealed a novel F-actin binding motif in a Legionella pneumophila lysine fatty acyltransferase [PDF]
eLifeLegionella pneumophila is an opportunistic bacterial pathogen that causes Legionnaires’ disease. To establish an intracellular niche conducive to replication, L.
Wenjie W Zeng +4 more
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F-actin Bundle Sedimentation Assay [PDF]
Bio-Protocol, 2019 Understanding the molecular mechanism governing the higher-order regulation of actin dynamics requires chemically-defined and quantitative assays. Recently, the membrane remodeling large GTPase, dynamin, has been identified as a new actin cross-linking ...
Shan-Shan Lin +2 more
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Characterization of ring-like F-actin structure as a mechanical partner for spindle positioning in mitosis. [PDF]
PLoS ONE, 2014 Proper spindle positioning and orientation are essential for accurate mitosis which requires dynamic interactions between microtubule and actin filament (F-actin).
Huan Lu +9 more
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Histones bundle F-actin filaments and affect actin structure. [PDF]
PLoS ONE, 2017 Histones are small polycationic proteins complexed with DNA located in the cell nucleus. Upon apoptosis they are secreted from the cells and react with extracellular polyanionic compounds.
Edna Blotnick, Asaf Sol, Andras Muhlrad
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Cell stress promotes the association of phosphorylated HspB1 with F-actin. [PDF]
PLoS ONE, 2013 Previous studies have suggested that the small heat shock protein, HspB1, has a direct influence on the dynamics of cytoskeletal elements, in particular, filamentous actin (F-actin) polymerization.
Joseph P Clarke, Karen M Mearow
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Cells, 2020 The crosstalk between actin and actin-related proteins (Arps), namely Arp2 and Arp3, plays a central role in facilitating actin polymerization in the cytoplasm and also in the nucleus.
Shota Yamazaki +6 more
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Structural polymorphism in F-actin [PDF]
Nature Structural & Molecular Biology, 2010 Actin has maintained an exquisite degree of sequence conservation over large evolutionary distances for reasons that are not understood. The desire to explain phenomena from muscle contraction to cytokinesis in mechanistic detail has driven the generation of an atomic model of the actin filament (F-actin).
Galkin, Vitold E. +3 more
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Cysteine-rich protein 2 accelerates actin filament cluster formation. [PDF]
PLoS ONE, 2017 Filamentous actin (F-actin) forms many types of structures and dynamically regulates cell morphology and movement, and plays a mechanosensory role for extracellular stimuli. In this study, we determined that the smooth muscle-related transcription factor,
Takanori Kihara +4 more
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Real-time analysis of F-actin fluctuation in living cells with quasi super-resolution technique
Journal of Biomechanical Science and Engineering, 2022 Actin filaments play significant roles in many essential cellular processes including muscle contraction, cell motility, vesicle and organelle movement, cell signaling, and mechano-sensing mechanism of cells.
Tomoteru OKA +2 more
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