Results 171 to 180 of about 16,055,310 (231)

Biocatalysts for Peptide Geranylation With Linear and Cyclic Prenyl Groups

open access: yesAngewandte Chemie International Edition, EarlyView.
A combination of genome mining, synthetic biology, and biocatalytic assays revealed enzymes that install linear and cyclized prenyl moieties on ribosomally or chemically synthesized peptides. The promiscuity of both enzymes, while being specific for modification of C‐terminal tryptophans, enables enzymatic access to peptide terpenoid hybrids.
Sarolt Magyari   +10 more
wiley   +1 more source

Pre-clinical efficacy of a C4BP hexameric IgG Fc fusion protein against Neisseria gonorrhoeae. [PDF]

open access: yesPLoS One
Shaughnessy J   +12 more
europepmc   +1 more source

Diol Chain‐Length Effects in Adipate and Succinate Polyesters for Thermoplastic Polyurethanes

open access: yesJournal of Applied Polymer Science, EarlyView.
This study examines 20 aliphatic polyesters as soft segments for thermoplastic polyurethanes (TPU), synthesized from adipic or succinic acid and diols (C2, C3, C4, C5, and C6). A pronounced odd‐even effect shows that even diols crystallize, while odd diols remain amorphous.
Dario Brand   +4 more
wiley   +1 more source

A new occurrence of tetrapod footprints from the Late Triassic of the Candelária Sequence, Brazil

open access: yesThe Anatomical Record, EarlyView.
Abstract The Hyperodapedon Assemblage Zone of the Candelária Sequence (Santa Maria Supersequence, Paraná Basin) preserves one of the most significant Late Triassic continental vertebrate assemblages in southern Brazil. Despite the relatively well‐documented body fossil record from this interval, ichnological records remain comparatively scarce.
Murilo Andrade‐Silva   +1 more
wiley   +1 more source

Accelerating Phosphate Transport Across Membranes via Synergistic Chemical-Electrochemical Carriers. [PDF]

open access: yesAngew Chem Int Ed Engl
Xia L   +9 more
europepmc   +1 more source

Bioerosion traces in bones reveal an increase in ethological diversity in the insect exploitation of carcasses in the late Triassic

open access: yesThe Anatomical Record, EarlyView.
Abstract This study presents the first detailed description of bioerosion traces produced by insects in bones from the Santa Cruz Sequence (early Carnian, Santa Maria Supersequence, Brazil). An array of traces is reported, consisting of notches, a tube, trails of grooves attributed to the ichnotaxon Osteocallis mandibulus and ornamented depressions ...
Lucca S. Cunha   +2 more
wiley   +1 more source

Factors Associated With Self-reported Family History of Pelvic Floor Disorders. [PDF]

open access: yesUrogynecology (Phila)
Zabriskie HA   +3 more
europepmc   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

open access: yesAnimal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen   +2 more
wiley   +1 more source

Higher Complement C4 Gene Copy Number Constitutes a Shared Genetic Risk Factor for Giant Cell Arteritis and IgA Vasculitis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Low copy number (CN) of complement C4 isoforms and high CN of retroviral HERV‐K elements are known risk factors for many immune‐mediated inflammatory diseases (IMIDs), often showing sex‐biased effects. Here, we assessed whether CN variation within the C4 gene contributes to giant cell arteritis (GCA) and IgA vasculitis (IgAV), two complex ...
Laura Martínez‐Gutiérrez   +295 more
wiley   +1 more source

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