Results 91 to 100 of about 4,372,209 (230)

Fibrilpaint: A Class of Amyloid‐Targeting Peptides

Chemistry – A European Journal, EarlyView.
FibrilPaints are modular peptides engineered to recognize amyloid fibrils. By systematically varying charge, sequence, and termini, their binding behavior can be tuned while retaining recognition. Successful binding ″paints″ fibrils for visualization and opens routes toward targeted degradation and diagnostic applications.
Júlia Aragonès Pedrola, Françoise A. Dekker, Katrin Guttmann, Litske M. van Leeuwen, Shalini Singh, Guy Mayer, Tommaso Garfagnini, Assaf Friedler, Stefan G. D. Rüdiger   +8 more
wiley   +1 more source

Pleiotropic effects of factor Xa and thrombin:what to expect from novel anticoagulants

, 2014
Factor Xa and thrombin are well-known components of the coagulation cascade and have been proven to be viable targets for effective anticoagulation treatment. However, accumulating evidence suggests that these serine proteases are also crucial modulators
ten Cate, Hugo, I. C. Van Gelder, de Jong, Anne Margreet, U. Schotten, H. ten Cate, H. M. H. Spronk, Schotten, Ulrich, H. J. Crijns, Spronk, Henri M. H., Crijns, Harry J., Van Gelder, Isabelle C., A. M. de Jong   +11 more
core   +1 more source

Direct thrombin inhibitors and factor Xa inhibitors for atrial fibrillation [PDF]

, 2017
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effectiveness of direct thrombin inhibitors and factor Xa inhibitors on clinical outcomes in patients with ...
Tracy W Tai, Mahtani, Kamal, Kamal R Mahtani, Heneghan, Carl, Carl J Heneghan, Tai, TW   +5 more
core   +1 more source

Analysis of Radial Heat Transfer in Cooled Fixed‐Bed Reactors by One‐ and Two‐Dimensional Models

Chemie Ingenieur Technik, EarlyView.
Exothermic fixed‐bed reactors are analyzed using 1D and 2D models. Radial temperature profiles from the 2D model enable optimization of the 1D approach via adjusted overall heat transfer coefficient. Derived correlations improve prediction accuracy, whereas thermal runaway behavior and model sensitivity are evaluated. ABSTRACT Exothermic reactions in a
Cora Bischoff, Andreas Jess
wiley   +1 more source

Waste activated sludge high‐rate treatment of septage: Stabilization phase trials and comparison with winery wastewater treatment

The Canadian Journal of Chemical Engineering, EarlyView.
Performance evaluation of the waste activated sludge high‐rate (WASHR) process for septic wastewater treatment. Abstract The waste‐activated sludge high‐rate (WASHR) process is evaluated as a batch‐mode pre‐treatment for actual septage using a high‐rate contact stabilization (HRCS) approach.
Arman Shirali, Melody Blythe Johnson, Mehrab Mehrvar   +2 more
wiley   +1 more source

Factor Xa Activates Endothelial Cells by a Receptor Cascade Between EPR-1 and PAR-2

, 2000
—In addition to its pivotal role in hemostasis, factor Xa binds to human umbilical vein endothelial cells through the recognition of a protein called effector cell protease receptor (EPR-1).
Jean-Marc Herbert, Paul Schaeffer, Corinne Michaux, Françoise Bono, Jean-Pascal Hérault, Anne-Laure Nestor, Jean-Claude Guillemot   +6 more
core   +1 more source

Speaking About Artificial Intelligence for Sustainability—How Employees’ Perception of Credibility Shapes Their Initial Attitudes Toward AI Adoption

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Companies increasingly claim to adopt artificial intelligence (AI) not only for economic but also for ecological and social purposes. However, in light of rising greenwashing, bluewashing, and ethics washing, the impact of the communicated rationale on employees' initial attitude toward AI introduction remains unclear.
Marco Baumgartner, Tobias Kopp, Regina Kempen, Steffen Kinkel   +3 more
wiley   +1 more source

Anode Materials Requirements for Potassium Ion Batteries: Challenges and Future Possibilities

EcoEnergy, EarlyView.
This work identifies a critical scale‐up gap between laboratory battery research and industrial targets, driven by low active‐mass loadings and the omission of full‐cell metrics. We outline concrete strategies to bridge this divide, shifting focus toward high‐loading electrodes (> 3 mg cm−2) to ensure practical commercial viability of potassium ion ...
Md. Robiul Alam, Sahithi Thatipamula, Muhammad Waqas Khan, Suraj Loomba, Sharafadeen Gbadamasi, Muhammad Haris, Xian Jian, Asif Mahmood, Mahdokht Shaibani, Nasir Mahmood   +9 more
wiley   +1 more source

Is the use of low molecular weight heparin a rational choice during pregnancy in patients with a mechanical heart valve: a report of three cases

Türk Kardiyoloji Derneği Arşivi, 2019
Pregnancy is associated with an increased risk of valve thrombosis in patients with a mechanical prosthetic heart valve. The administration of low molecular weight heparin (LMWH) with regular anti-factor Xa assessment is a recommended treatment modality ...
Ahmet Güner, Emrah Bayam, Semih Kalkan, Sabahattin Gündüz, Mehmet Özkan   +4 more
doaj   +1 more source

Photothermal–Magnetocaloric Coupled Evaporators for Actively Adjustable Water Evaporation and Oil–Water Purification in Complex Environments

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A photothermal–magnetocaloric coupled aerogel evaporator is developed for actively adjustable water evaporation in complex environments. Magnetocaloric heating provides active energy compensation under low‐light conditions and disrupts interfacial hydrogen‐bond networks to promote evaporation.
Jingbo He, Dan Yang, Chunyu Yang, Ruihan Guo, Mengshu Xu, Dongxue Wang, Zhuoran Yang, Jian Huang, Wei Guo   +8 more
wiley   +1 more source