The impact of systemic long‐term medications for the development of age‐related macular degeneration
Acta Ophthalmologica, EarlyView.Abstract Purpose Age‐related macular degeneration (AMD) is a leading cause of central vision loss in the elderly; however, the systemic factors that modulate its incidence and progression remain unclear. We sought to determine whether long‐term use of systemic medications, including diabetes and antithrombotic medications, corticosteroids and ...
Hanna Heloterä +3 more
wiley +1 more source
Archaeometry, EarlyView.ABSTRACT Provenance reconstruction using strontium and lead stable isotopes can produce complex multidimensional fingerprints, challenging traditional methods. Identifying nonlocals, who migrated between sites, is a major task. Migrants are identifiable by divergent multi‐isotope fingerprints due to isotopic mixing between origin and destination sites.
Andrea Göhring +8 more
wiley +1 more source
British Journal of Educational Psychology, EarlyView.Abstract Background University students around the world learn English as a foreign language (EFL) as it is considered vital for their post‐education opportunities locally and internationally. Optimising English language learning in EFL classrooms at the university is thus important.
Yoshiyuki Nakata +3 more
wiley +1 more source
Experimental Determination of Calcite Solubility in H2O‐KCl‐NaCl‐LiCl Solutions at 700°C and 8 kbar
Geophysical Monograph Series, Page 245-257., 2020 This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.
Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions
Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
James Eguchi, Yuan Li, Craig E. Manning
wiley +1 more source
Regularized reduced rank regression for mixed predictor and response variables
British Journal of Mathematical and Statistical Psychology, EarlyView.Abstract In this paper, we introduce the Generalized Mixed Regularized Reduced Rank Regression model (GMR4), an extension of the GMR3 model designed to improve performance in high‐dimensional settings. GMR3 is a regression method for a mix of numeric, binary and ordinal response variables, while also allowing for mixed‐type predictors through optimal ...
Lorenza Cotugno +2 more
wiley +1 more source
Enoxaparin Dosing and Target anti-Factor Xa Achievement in Infants by Postmenstrual Age. [PDF]
J Pediatr Pharmacol TherPerez D, Mathew K.
europepmc +1 more source
거머리로부터 혈액응고에 관련된 kallikrein 및 factor Xa 억제제의 특성분석
, 1998 학위논문(박사) - 한국과학기술원 : 생물과학과, 1998.8, [ viii, 87 p. ]I. Plasma kallikrein inhibitor: A new serine proteinase inhibitor of plasma kallikrein was screened and purified from a native Korean leech species, Hirudo nipponia.
Kim, Dong-Ryoung, 김동령
core
Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries
British Journal of Pharmacology, EarlyView.Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley +1 more source
Residue‑resolved dynamically averaged interaction analysis of direct factor Xa inhibitors by MD‑FMO combination calculations. [PDF]
J Comput Aided Mol DesYoshine R +8 more
europepmc +1 more source