Results 101 to 110 of about 36,441 (245)

Pharmacodynamics and Pharmacokinetics of oral factor Xa inhibitors

Clinical Pharmacology: Advances and Applications, 2015
Pontus B Persson Institute of Vegetative Physiology, Berlin, GermanyApixaban and rivaroxaban are oral factor Xa inhibitors. In a recent issue of Clinical Pharmacology: Advances and Applications, Frost et al compare apixaban (2.5 mg, twice daily) to ...
Persson PB
doaj  

Stabilization of Cu Species in UiO‐66 Metal–Organic Framework for CO2‐to‐Methanol: Insights From Operando X‐ray and Electron Microscopy Studies

Small, EarlyView.
This study reveals how a zirconium‐based metal–organic framework (UiO‐66) stabilizes copper species during CO2 hydrogenation to methanol. Operando X‐ray spectroscopy, electron microscopy, and theory show that zinc promotes highly dispersed copper and suppresses particle growth, while the framework dynamically responds to reaction intermediates.
Anna Liutkova, Fabio André Peixoto Esteves, Marianela López Romero, Margareth S. Baidun, Anastasia Molokova, Davide Salusso, Kirill A. Lomachenko, Andrea Testino, Alexander A. Kolganov, Evgeny A. Pidko, Emiliya Poghosyan, Marco Ranocchiari   +11 more
wiley   +1 more source

Changes in Internal Structure and Dynamics upon Binding Stabilise the Nematode Anticoagulant NAPc2

Biomolecules
Abnormal blood coagulation is a major health problem and natural anticoagulants from blood-feeding organisms have been investigated as novel therapeutics.
Elaine Woodward, Brendan M. Duggan
doaj   +1 more source

Boosting Performance of PANI@N‐WHL‐AC by a Modified Water‐in‐Salt‐Electrolyte Strategy for Zinc‐Ion Batteries

Small, EarlyView.
MSA‐regulated water‐in‐salt electrolyte enables dual‐ion (Zn2+/H+) storage and stabilizes Zn plating/stripping in PANI@N‐doped biomass‐derived carbon cathodes. The synergistic electrolyte–electrode engineering delivers high energy density and long‐term cycling stability for aqueous zinc‐ion batteries.
Olbana Itana, Asmamew Taye, Xinwen Peng, Varsha Joseph, Amare Aregahegn, Reverant Crispin, Shimelis Admassie, Ziyauddin Khan   +7 more
wiley   +1 more source

Construction and Expression of Recombinant LL-37 as Histag-SUMO Fusion Protein with Factor Xa Cleavage Site

Hayati Journal of Biosciences
LL-37 is an antimicrobial protein expressed by the CAMP gene in humans. This protein has various antibacterial, antiviral and anticancer effects. Expressing LL-37 as a heterologous protein in E. coli cells has its challenges.
Tina Rostinawati, Imam Adi Wicaksono, Bernap Dwi Putra Sitinjak, Muhammad Fadhlillah   +3 more
doaj   +1 more source

Perfluorohexanone for Clean Fire Suppression: Mechanisms, System Design, Applications, and Future Directions

Safety Science and Technology, EarlyView.
Driven by halon and high GWP agent phase out, perfluorohexanone is increasingly deployed in enclosures such as data centers, marine machinery spaces, and industrial process lines. This review summarizes application performance, discharge and distribution design, material compatibility, and byproduct control and maps practical gaps for large volume and ...
Zhilei Yu, Haibin Dong, Yanfeng Sheng, Xuelei Xian, Dehua Zhang, Feiran Li, Liang Liu, Junchao Zhao, Heping Zhang   +8 more
wiley   +1 more source

Monitoring unfractionated heparin in ECMO and cardiac surgery: the search for a valid reference standard

Frontiers in Medicine
Unfractionated heparin remains the standard anticoagulant during cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO). Despite decades of clinical use, however, no universally validated reference method exists for measuring ...
Christian F. Weber, Christian F. Weber, Kai Zacharowski, Andreas Calatzis, Marie L. Lindner   +4 more
doaj   +1 more source

Behavior of manufactured sand and recycled coarse aggregate concrete‐filled steel tubular stub columns with circular section

Structural Concrete, EarlyView.
Abstract Accelerated urbanization has intensified environmental concerns due to excessive natural resource consumption and construction waste generation. Circular concrete‐filled steel tube (CFST) columns incorporating manufactured sand recycled coarse aggregate (MS‐RCA) concrete have emerged as an innovative composite element offering notable ...
Minsheng Guan, Qi Chen, Gang Wang, Aiguo Xiong, Ying Wang, Le Li, Anne W. M. Ng, Qing Quan Liang   +7 more
wiley   +1 more source

Deformation and strength of grouted sleeve connectors in pre‐fabricated concrete structures: Mechanisms and analytical modeling

Structural Concrete, EarlyView.
Abstract Grouted sleeve connectors (GSCs) are widely used in precast/prefabricated concrete structures. To ensure force transfer, connectors are often overdesigned in length. This practice has an unintended consequence of reducing the plastic deformation capacity of the connection region and hence the displacement ductility of the precast structure as ...
Hongning Ye, Yong Lu
wiley   +1 more source

Management of heparin-induced thrombocytopenia with factor xa inhibitors: A systematic review

Thrombosis Update
Heparin-induced thrombocytopenia (HIT) is a rare but severe prothrombotic disorder that develops in patients exposed to heparin products. Diagnosis is associated with significant morbidity and mortality.
Colton Jones, Abiodun Idowu, Elvis Obomanu, Raymond Smith, Karecia Byfield, Avinash Ramkissoon, Kevin Bryan Lo, Ryan Mayo   +7 more
doaj   +1 more source