Results 121 to 130 of about 12,986,553 (373)

gnSPADE: Incorporating Gene Network Structures Enhances Reference‐Free Deconvolution in Spatial Transcriptomics

Advanced Intelligent Systems, EarlyView.
gnSPADE integrates gene‐network structures into a probabilistic topic modeling framework to achieve reference‐free cell‐type deconvolution in spatial transcriptomics. By embedding gene connectivity within the generative process, gnSPADE enhances biological interpretability and accuracy across simulated and real datasets, revealing spatial organization ...
Aoqi Xie, Yuehua Cui
wiley   +1 more source

Epstein–Barr Virus, Lower Vitamin D, Low Sun Exposure, and HLA‐DRB1*1501 Risk Variant Share Common Epigenetic Pathways Leading to Multiple Sclerosis Onset

Annals of Neurology, EarlyView.
Objectives Multiple sclerosis (MS) onset risk factors include Epstein–Barr virus (EBV) indices (including host response), lower serum 25‐vitamin D (25(OH)D) levels, low sun exposure, and HLA‐DRB1*1501. The underlying molecular mechanisms are unclear. Here, we examined mediation through differential DNA methylation (DNAm) to better understand possible ...
Steve Simpson‐Yap, Ellen Morwitch, Samuel A. Tanner, Sarah M. Thomson, Alex Eisner, Rod A. Lea, Trevor J. Kilpatrick, Jeannette Lechner‐Scott, Rodney J. Scott, Alexandre Xavier, Vicki E. Maltby, Robyn M. Lucas, Bruce V. Taylor, Brett A. Lidbury, Simon A. Broadley, Ingrid van der Mei, Mehari Woldemariam Merid, Boris Novakovic, Richard Saffery, Anna Karin Hedström, Pernilla Stridh, Tomas Olsson, Maja Jagodic, Lars Alfredsson, Anne‐Louise Ponsonby, for the Ausimmune Investigator Group, Caron Chapman, Alan Coulthard, Keith Dear, Terry Dwyer, Trevor Kilpatrick, Robyn Lucas, Tony McMichael, Anne‐Louise Ponsonby, Bruce Taylor, Patricia Valery, Ingrid van der Mei, David Williams   +37 more
wiley   +1 more source

Heavy is the Crown: Crown Ether Modulation of Cobalt Porphyrin CO2 Electroreduction in Zero‐Gap Electrolyzers

Angewandte Chemie International Edition, EarlyView.
The implementation of crown ethers into the ligand of cobalt porphyrins benefits the electrochemical CO2 reduction in the several ways: (1) the reduction potential is lowered in presence of K+; (2) it boosts the CO generation in Zero‐Gap Electrolyzers and (3) ensures complex stability during electrolysis.
Wiebke Wiesner, Christian Wilhelm, Rahel Cornelia Hoffmann, Peter Stahl, Kevinjeorjios Pellumbi, Julia Jökel, Ivana Ivanović‐Burmazović, Ulf‐Peter Apfel   +7 more
wiley   +1 more source

Residential irrigation as a driver of urban bird communities [PDF]

, 2009
*Background/Question/Methods* The demand for fresh water has largely outpaced supply both globally and locally with current water management policies unable to meet the needs of urban, agricultural, and industrial activities.
Bradley W. Schleder, Madhusudan Katti, Sarah Wallace   +2 more
core   +1 more source

Flow of Elastoviscous Nanofluid Through an Elongating Surface With Dissipative Heat: A Confluent Hypergeometric Solution

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Thermal energy transport likely through polymer extrusion, cooling of metallic plates, and chemical processing equipment relating to the flow of viscoelastic nanofluid has a greater role in engineering because of its elastic characteristics.
Rupa Baithalu, S. R. Mishra, Ram Prakash Sharma, Laxmipriya Swain   +3 more
wiley   +1 more source

Factor Xa subsite mapping by proteome-derived peptide libraries improved using WebPICS, a resource for proteomic identification of cleavage sites [PDF]

, 2017
Proteomic identification of protease cleavage site specificity (PICS) is a recent proteomic approach for the easy mapping of protease subsite preferences that determines both the prime- and non-prime side specificity concurrently.
dem Keller, Ulrich auf, Overall, Christopher M., Schilling, Oliver   +2 more
core  

Path Integral Solution of Linear Second Order Partial Differential Equations I. The General Construction [PDF]

, 2004
A path integral is presented that solves a general class of linear second order partial differential equations with Dirichlet/Neumann boundary conditions. Elementary kernels are constructed for both Dirichlet and Neumann boundary conditions.
Abraham, Cartier, Cartier, Cartier, Dunkl, Duru, Dynkin, Elworthy, Feynman, Freidlin, Friedman, Glimm, Grosche, J. LaChapelle, Lachapelle, Sagan, Young   +16 more
core   +2 more sources

Optimization and Characterization of Aspirin‐ and Ibuprofen‐Loaded Lipid‐Based Nanoparticle Synthesis for Antibacterial Activity and Cytotoxic Effect

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Lipid‐based nanoparticles (LNPs) are favored for drug delivery because of their low toxicity, high biocompatibility, ability to self‐assemble into nanoparticles, and ability to enhance drug bioavailability, thereby improving drug release modulation and pharmacokinetics.
Gulizar Caliskan, Smyrna Ergonul, Zuhal Naz Cansu, Busra Kaplan   +3 more
wiley   +1 more source

Discovery of Extremely Embedded X-ray Sources in the R Coronae Australis Star Forming Core

, 2005
With the XMM-Newton and Chandra observatories, we detected two extremely embedded X-ray sources in the R Corona Australis (R CrA) star forming core, near IRS 7.
Alan T. Tokunaga, Anderson I. M., Beate Stelzer, Hamaguchi K., Harju J., Henning T., Kenji Hamaguchi, Knude J., Ko Nedachi, Koyama K., Mewe R., Michael F. Corcoran, Naoto Kobayashi, Nicholas E. White, Rob Petre, Saraceno P., Stelzer B., Tsujimoto M.   +17 more
core   +1 more source

Effect of Time to Start of Biologic Therapy on Treatment Response in Childhood Arthritis: Results From the UCAN CAN‐DU Cohort

Arthritis &Rheumatology, EarlyView.
Objective To estimate the effect of time from symptom onset to start of biologic treatment on achieving inactive arthritis within six months in a cohort of patients with juvenile idiopathic arthritis (JIA). Methods The international UCAN CAN‐DU study prospectively enrolled patients with JIA across Canada and the Netherlands.
Jelleke B. de Jonge, Sytze de Roock, Dieneke Schonenberg‐Meinema, J. Merlijn van den Berg, Deborah A. Marshall, Sebastiaan J. Vastert, Rae S. M. Yeung, Joost F. Swart, Susanne M. Benseler, on behalf of the UCAN CAN‐DU and UCAN CURE consortia, Adam Huber, Bianca Lang, Chelsea DeCoste, Elizabeth Stringer, Suzanne Ramsey, Alan Rosenberg, Kate Neufeld, Mehul Jariwala, Tristan Kerr, Alexander Mosoiu, Alisa Rachlis, Amy Xu, Arthur Cheng, Brenleigh Jebb, Brian Feldman, Bruno Pereira, Deborah Levy, Dilan Dissanayake, Elizaveta Limenis, Evelyn Rozenblyum, Harper Cheng, Jennifer Ji Young Lee, Lynn Spiegel, Rayfel Schneider, Ronald Laxer, Ruud Verstegen, Shirley Tse, Trang Duong, Andrea Human, David Cabral, Herman Tam, Jaime Guzman, Kim Morishita, Kristin Houghton, Lori Tucker, Mercedes Chan, Ross Petty, Tommy Gerschman, Annet van Royen‐Kerkhof, Berent Prakken, Erika Van Nieuwenhove, Marc Jansen, Nico Wulffraat, Ciarán Duffy, Nadia Luca, Roman Jurencak, Tala El Tal, Claire LeBlanc, Gaëlle Chédeville, Piya Lahiry, Rosie Scuccimarri, Sarah Campillo, Clare Hutchinson, Daniah Basodan, Dax G. Rumsey, Hon Yan Ng, Jeanine McColl, Lillian Lim, Tara McGrath, Danielle Brinkman, Petra Hissink Muller, Elizabeth Legger, Wineke Armbrust, Ellen Schatorje, Esther Hoppenreijs, Elodie Boudes, Gillian Currie, Heinrike Schmeling, Muhammed Dhalla, Nicole Johnson, Paivi Miettunen, Ravneet Sran, Rebeka Stevenson, Erkan Demirkaya, Jonathan Park, Roberta Berard, Giske Biesbroek, Mariken Gruppen, Gordon Soon, Joseph Cafazzo, Liane Heale, Michelle Batthish, Tania Cellucci, Lily Lim, Maarten IJzerman, Marinka Twilt, Marleen Verkaaik, Philomine van Pelt, Sylvia Kamphuis, Michelle Kip, Nickolas Blanchette, Paul Dancey, Regina de Geus   +102 more
wiley   +1 more source