Results 21 to 30 of about 242,673 (264)
Interaction of prothrombin with factor Va-phospholipid complexes [PDF]
, 1984 The effects of factor Va and the phospholipid-binding fragment of factor Va [factor Va light chain (LC), Mr 80000] on the binding of prothrombin, factor X, and factor Xa to phospholipid vesicles are reported.
Hemker, H. Coenraad +2 more
core +2 more sources
Efficacy and Toxicity of Factor Xa Inhibitors
Journal of Pharmacy & Pharmaceutical Sciences, 2013 Venous thromboembolism (VTE) is a serious disease that is often neglected, and effective and safe antithrombotic treatments are a public health priority. New antithrombotics such as rivaroxaban, apixaban, betrixaban, edoxaban, darexaban, TAK-442, LY517717, eribaxaban, otamixaban are being developed to overcome current therapeutic limitations.
Bondarenko, Maryna +4 more
openaire +6 more sources
Low‐Loss Far‐Infrared Surface Phonon Polaritons in Suspended SrTiO3 Nanomembranes
Advanced Functional Materials, EarlyView.The low‐loss, highly confined, and thickness‐tunable surface phonon polaritons are demonstrated in the far‐infrared regime within transferable freestanding SrTiO3 membranes, achieving high figures of merit comparable to the previous record values from the vdW materials.
Konnor Koons +8 more
wiley +1 more source
Learning with the Amerindians: the evaluation of pelvic floor disorders among indigenous women who live in the Xingu Indian Park,Brazil [PDF]
, 2008 Objective: to evaluate the pelvic floor muscles and the incidence of pelvic organ prolapse among indigenous women who live in Xingu Indian Park, Mato Grosso, Brazil. Methods: observational study with 377 indigenous women, mean age 31+/-15 years,
Claudia Cristina Takano +3 more
core +2 more sources
Oral Direct Factor Xa Inhibitors [PDF]
Circulation Research, 2012 Vitamin K antagonists, such as warfarin, have been the mainstay of oral anticoagulation for many decades. Although effective, warfarin has numerous limitations, including a variable dose requirement from patient to patient because of differences in dietary vitamin K intake, common genetic polymorphisms, and multiple drug interactions that affect its ...
Jeffrey I. Weitz +2 more
openaire +2 more sources
Advanced Materials, EarlyView.Reversible protonic ceramic electrochemical cells (R‐PCECs) face challenges from sluggish and unstable oxygen reduction and evolution reactions in the air electrode. This review discusses recent progress in triple‐conducting air electrodes, emphasizing mechanisms, performance factors, and design strategies, offering guidance for creating efficient and ...
Xi Chen +8 more
wiley +1 more source
Slug-based epithelial-mesenchymal transition gene signature is associated with prolonged time to recurrence in glioblastoma [PDF]
, 2011 Background We previously identified a precise stage-associated gene expression signature of coordinately expressed genes, including the transcription factor Slug (SNAI2) and other epithelial mesenchymal transition (EMT) markers, present in ...
Darrell J. Yamashiro +4 more
core +1 more source
The new factor Xa inhibitor: Apixaban
Journal of Pharmacology and Pharmacotherapeutics, 2014 Cardiovascular diseases are still the most important cause of morbidity and mortality worldwide and anti-thrombotic treatment is widely used as a result. The currently used drugs include heparin and its derivatives, vitamin K antagonists, though efficacious, have their own set of limitations like unpredictable pharmacokinetic profile, parenteral route (
Sangeeta Bhanwra, Kaza Ahluwalia
openaire +4 more sources
Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules
Advanced Materials Interfaces, EarlyView.This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania +2 more
wiley +1 more source
Pregnancy Obstructs Involution Stage II of the Mammary Gland in Cows: General Biological Implications [PDF]
, 2007 *Background* Repeated research findings over the last 4 decades show that involution of mammary glands in dairy cows did not regress to same extend as that noticed in other mammalian species. *Methodology/Principal Findings ...
Ana-Maria Anug +3 more
core +1 more source