Results 51 to 60 of about 12,986,553 (373)

The Quasar Main Sequence explained by the combination of Eddington ratio, metallicity and orientation [PDF]

, 2019
We address the effect of orientation of the accretion disk plane and the geometry of the broad-line region (BLR) as part of an effort to understand the distribution of quasars in the optical plane of the quasar main sequence.
Czerny, Bożena, Marziani, Paola, Panda, Swayamtrupta   +2 more
core   +2 more sources

Edoxaban: an update on the new oral direct factor Xa inhibitor. [PDF]

, 2014
Edoxaban is a once-daily oral anticoagulant that rapidly and selectively inhibits factor Xa in a concentration-dependent manner. This review describes the extensive clinical development program of edoxaban, including phase III studies in patients with ...
A. John Camm, AC Skanes, AG Turpie, AJ Camm, AK Kakkar, AT Cohen, B Laulicht, BF Gage, BI Eriksson, BI Eriksson, BI Eriksson, BI Eriksson, BS Stambler, C Kearon, CB Granger, CT Ruff, DE Salazar, G Agnelli, G Agnelli, G Lu, G Raskob, G Raskob, H Masumoto, H Zahir, Henri Bounameaux, J Mendell, J Mendell, J Mendell, J Mendell, J Mendell, J Mendell, J Stampfuss, JH Alexander, JI Weitz, JL Mega, K Ogata, KL Furie, LT Grip, M Crowther, M Hori, M Pirmohamed, MR Lassen, MR Lassen, MR Lassen, MR Lassen, MR Patel, MS Bathala, MU Zafar, N Chung, N Matsushima, R Caterina De, R Caterina De, RP Giugliano, S Kaatz, S Schulman, S Schulman, S Schulman, SE Kimmel, SJ Connolly, SJ Connolly, SJ Connolly, SZ Goldhaber, T Fuji, T Fuji, T Fukuda, T Hulle van der, T Mikkaichi, T Wilke, T Yamashita, TI Verhoef, W Mueck, Y Falck-Ytter, Y Kuroda   +72 more
core   +1 more source

Accuracy of a Rapid Diagnostic Test for the Presence of Direct Oral Factor Xa or Thrombin Inhibitors in Urine—A Multicenter Trial

Thrombosis and Haemostasis, 2019
The rapid determination of the presence of direct oral anticoagulants (DOACs) in a patient remains a major challenge in emergency medicine and for rapid medical treatment decisions. All DOACs are excreted into urine.
J. Harenberg, J. Beyer-Westendorf, M. Crowther, J. Douxfils, I. Elalamy, P. Verhamme, R. Bauersachs, S. Hetjens, C. Weiss, I. Ahrens, Timo Bömicke, J. Herold, S. Marten, C. Naue, H. Darius, L. Reill, D. Dürschmied, Roland Giesen, C. Olivier, M. Grünewald, R. Klamroth, C. Kubicek-Hofmann, Ana-Marija Orlovic, F. Langer, M. Voigtländer, E. Lindhoff-Last, B. Zydek, F. Menzel, Cornelia Piper, Isgandarova Potratz, S. Schellong, C. Müller, U. Scholz, Michael Krause, C. Sucker, D. Trenk, J. Hromek, S. Leggewie, U. Overhoff, Fabian Krämer, Ulrich Wolf   +40 more
semanticscholar   +1 more source

Safety of 4-factor prothrombin complex concentrate (4F-PCC) for emergent reversal of factor Xa inhibitors

Journal of Intensive Care, 2018
BackgroundAlthough factor Xa inhibitors have become a popular choice for chronic oral anticoagulation, effective drug reversal remains difficult due to a lack of specific antidote.
J. Tao, E. Bukanova, S. Akhtar
semanticscholar   +1 more source

The eDAL Suite: Tools and Concepts for Primary Data Citation [PDF]

, 2010
Retrieval and citation of primary data is the important factor in the approaching age of “data science”. Digital data are easily shared, and just as easily wiped or lost.
Christian Colmsee, Jinbo Chen, Matthias Klapperstück, Matthias Lange, Matthias Lange, Steffen Flemming, Uwe Scholz   +6 more
core   +2 more sources

The Impact of Continuous Veno-Venous Hemodiafiltration on the Efficacy of Administration of Prophylactic Doses of Enoxaparin: A Prospective Observational Study

Pharmaceuticals, 2023
Background: Critically ill patients frequently require continuous renal replacement therapy (CRRT). During CRRT, particles up to 10 kDa in size, such as enoxaparin, may be removed. The aim of this study was to determine if patients receiving prophylactic
Aleksander Aszkiełowicz, Karol P. Steckiewicz, Michał Okrągły, Magdalena A. Wujtewicz, Radosław Owczuk   +4 more
doaj   +1 more source

Pharmacist recommendations for prophylactic enoxaparin monitoring and dose adjustment in trauma patients admitted to a surgical intensive care unit

Pharmacy Practice, 2019
Background: There is limited information describing pharmacist participation in prophylactic enoxaparin monitoring in the surgical intensive care unit (SICU).
Scrimenti A, Seabury RW, Miller CD, Ruangvoravat L, Darko W, Probst LA, Cwikla GM   +6 more
doaj   +1 more source

Prediction of inhibition constants of (R)-3-amidinophenylalanine inhibitors toward factor Xa by 2D-QSAR model

Vietnam Journal of Science, Technology and Engineering, 2022
A coagulation cascade forms through proteolytic reactions and involves different factors. There are two coagulation pathways, including intrinsic and extrinsic mechanisms, which converge by the formation of factor Xa.
Thi Bich Van Pham, Minh Hao Hoang
doaj   +1 more source

Factor Xa inhibitors for preventing recurrent thrombosis in patients with antiphospholipid syndrome: a longitudinal cohort study

Lupus, 2019
Objective The objective of this study was to clarify the efficacy and safety of factor Xa inhibitors for antiphospholipid syndrome patients in real world utilization. Methods This is a retrospective cohort study comprised of all consecutive patients with
Takahiro Sato, Hiroyuki Nakamura, Y. Fujieda, Naoki Ohnishi, N. Abe, M. Kono, M. Kato, K. Oku, T. Bohgaki, O. Amengual, S. Yasuda, Tatsuya Atsumi   +11 more
semanticscholar   +1 more source

Effect of a single Dialysis session on plasma Lp(a) levels in patients on Maintenance haemodialysis [PDF]

, 2011
Background: Cardiovascular disease (CVD) is a major cause of mortality in End stage renal disease (ESRD) patients on Maintenance haemodialysis (MHD).
Aparna R. Bitla, MM Suchitra, Prabhakar E. Reddy, PVLN Srinivasa Rao, Siva V. Kumar, Varikasuvu Seshadri Reddy   +5 more
core   +1 more source