Results 81 to 90 of about 1,255,893 (247)
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Medical school faculty productivity
Academic Medicine, 1976 W H, Pearse +3 more
openaire +3 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Revista Gestão & Saúde, 2015 Occupational stress studies with effort-reward imbalance at work in medical and nursing faculty have not been described in literature. Objectives: 1) To estimate the effort-reward imbalance and the overcommitment at work in medical and nursing faculty. 2)
Fernando de Camargo Aranha +4 more
doaj
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Acknowledgment to Referees 2024 [PDF]
Journal of Research Development in Nursing and MidwiferyThe editorial team at the Journal of Research Development in Nursing and Midwifery would like to extend our heartfelt gratitude and recognition to the reviewers who dedicated their time and expertise to review manuscripts for J Res Dev Nurs Midw in 2024.
Leila Mahasti Jouybari
doaj
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Iranian Journal of Nursing and Midwifery ResearchBackground: Faculty members and medical staff are prone to burnout syndrome. Burnout has harmful consequences for the organization, society, and individual life.
Hassan Ebrahimpour-Sadagheyani +1 more
doaj +1 more source