Results 71 to 80 of about 1,443,501 (316)

Minutes: Medical School Faculty Assembly, May 23, 2007

open access: yes, 2007
University of Minnesota. Medical School Faculty Assembly. (2007). Minutes: Medical School Faculty Assembly, May 23, 2007.
University of Minnesota. Medical School Faculty Assembly
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Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Mentoring Matters: Faculty's Role in Developing Competent Doctors

open access: yesGAIMS Journal of Medical Sciences
The integration of structured mentoring programs within the medical curriculum and the inclusion of mentoring sessions in faculty development programs represent a forward-thinking approach by the NMC.
Mandar Chandrachood
doaj   +1 more source

Minutes: Medical School Faculty Assembly, May 16, 2005

open access: yes, 2005
University of Minnesota. Medical School Faculty Assembly. (2005). Minutes: Medical School Faculty Assembly, May 16, 2005.
University of Minnesota. Medical School Faculty Assembly
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Minutes: Medical School Faculty Assembly, June 13, 2002

open access: yes, 2002
University of Minnesota. Medical School Faculty Assembly. (2002). Minutes: Medical School Faculty Assembly, June 13, 2002.
University of Minnesota. Medical School Faculty Assembly
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Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Minutes: Medical School Faculty Assembly, May 8, 2003

open access: yes, 2003
University of Minnesota. Medical School Faculty Assembly. (2003). Minutes: Medical School Faculty Assembly, May 8, 2003.
University of Minnesota. Medical School Faculty Assembly
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Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Minutes: Medical School Faculty Assembly, November 29, 2005

open access: yes, 2005
University of Minnesota. Medical School Faculty Assembly. (2005). Minutes: Medical School Faculty Assembly, November 29, 2005.
University of Minnesota. Medical School Faculty Assembly
core  

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