Results 61 to 70 of about 1,443,501 (316)

Minutes: Medical School Faculty Assembly, November 17, 2008

open access: yes, 2008
University of Minnesota. Medical School Faculty Assembly. (2008). Minutes: Medical School Faculty Assembly, November 17, 2008.
University of Minnesota. Medical School Faculty Assembly
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Minutes: Medical School Faculty Assembly, May 7, 2001

open access: yes, 2001
University of Minnesota. Medical School Faculty Assembly. (2001). Minutes: Medical School Faculty Assembly, May 7, 2001.
University of Minnesota. Medical School Faculty Assembly
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Minutes: Medical School Faculty Assembly, May 26, 2009

open access: yes, 2009
University of Minnesota. Medical School Faculty Assembly. (2009). Minutes: Medical School Faculty Assembly, May 26, 2009.
University of Minnesota. Medical School Faculty Assembly
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

New tools for systematic evaluation of teaching qualities of medical faculty: results of an ongoing multi-center survey.

open access: yesPLoS ONE, 2011
BackgroundTools for the evaluation, improvement and promotion of the teaching excellence of faculty remain elusive in residency settings. This study investigates (i) the reliability and validity of the data yielded by using two new instruments for ...
Onyebuchi A Arah   +3 more
doaj   +1 more source

Minutes: Medical School Faculty Assembly, May 11, 2006

open access: yes, 2006
University of Minnesota. Medical School Faculty Assembly. (2006). Minutes: Medical School Faculty Assembly, May 11, 2006.
University of Minnesota. Medical School Faculty Assembly
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Clinical mentoring programs for medical students, practical points in design, implementation and evaluation

open access: yesJournal of Medical Education and Development, 2018
Introduction: Although Mentoring programs are one of the essential reasons of professional development for medical students, most academics experience lack of them.
Saeed Pourhassan
doaj  

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