Results 81 to 90 of about 1,443,501 (316)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Paradigms in the teaching of medical research: a view from the classroom, to the classroom

Revista Ciencias Biomédicas, 2010
The guidelines of the University of Cartagena for comprehensive professional training, provide for the inclusion of the research component. In the medical program, research is the cornerstone for the construction of new knowledge, that today, directs the
Ramos Clason Enrique Carlos, Márquez-Cárdenas Evelio José   +1 more
doaj  

A formação do professor de Medicina como "intelectual": uma análise crítica

Revista Brasileira de Educação Médica
As diretrizes curriculares nacionais de 2001 demandam uma consistente formação em humanidades por parte do egresso da graduação em Medicina. A fim de cumprir essa exigência, caberia ao docente uma nova tarefa frente ao alunato, além da produção de ...
Marcos Antonio Almeida Santos
doaj   +1 more source

Memories of the medical faculty

Kazan medical journal, 1994
In August 1919, I came to Kazan from the wilderness of the Penza province (b. Chembarsky district, now Belinsky district of the Penza region, 50 km from the railway station), because in the spring of that year I applied to Kazan University with a request to enroll me in the mathematical department of physics. For admission to students, it was enough to
openaire   +1 more source

Minutes: Medical School Faculty Assembly, December 1, 2009

, 2009
University of Minnesota. Medical School Faculty Assembly. (2009). Minutes: Medical School Faculty Assembly, December 1, 2009.
University of Minnesota. Medical School Faculty Assembly
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Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Efetividade da Avaliação Programática do Estudante de Medicina: Estudo de Caso Baseado nas Impressões de Estudantes e Professores de uma Escola Médica Britânica

Revista Brasileira de Educação Médica
RESUMO A avaliação programática do estudante é uma abordagem relativamente nova, que tem como objetivo principal o aperfeiçoamento das condições de utilização dos diferentes métodos de avaliação, com vistas ao melhor cumprimento das funções da avaliação:
Luiz Ernesto de Almeida Troncon
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Minutes: Medical School Faculty Advisory Council, Feb. 1, 2005

, 2005
Faculty advisory council to the Dean of the Medical School.University of Minnesota. Medical School Faculty Advisory Council. (2005). Minutes: Medical School Faculty Advisory Council, Feb. 1, 2005. Retrieved from the University Digital Conservancy, https:/
University of Minnesota. Medical School Faculty Advisory Council
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