Results 81 to 90 of about 10,130,145 (265)

Minutes: Medical School Faculty Assembly, November 17, 2008

, 2008
University of Minnesota. Medical School Faculty Assembly. (2008). Minutes: Medical School Faculty Assembly, November 17, 2008.
University of Minnesota. Medical School Faculty Assembly
core  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Minutes: Medical School Faculty Assembly, October 16, 2006

, 2006
University of Minnesota. Medical School Faculty Assembly. (2006). Minutes: Medical School Faculty Assembly, October 16, 2006.
University of Minnesota. Medical School Faculty Assembly
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Efetividade da Avaliação Programática do Estudante de Medicina: Estudo de Caso Baseado nas Impressões de Estudantes e Professores de uma Escola Médica Britânica

Revista Brasileira de Educação Médica
RESUMO A avaliação programática do estudante é uma abordagem relativamente nova, que tem como objetivo principal o aperfeiçoamento das condições de utilização dos diferentes métodos de avaliação, com vistas ao melhor cumprimento das funções da avaliação:
Luiz Ernesto de Almeida Troncon
doaj   +1 more source

Minutes: Medical School Faculty Assembly, May 12, 2004

, 2004
University of Minnesota. Medical School Faculty Assembly. (2004). Minutes: Medical School Faculty Assembly, May 12, 2004.
University of Minnesota. Medical School Faculty Assembly
core  

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Minutes: Medical School Faculty Advisory Council, May 21, 2007

, 2007
Faculty advisory council to the Dean of the Medical School.University of Minnesota. Medical School Faculty Advisory Council. (2007). Minutes: Medical School Faculty Advisory Council, May 21, 2007. Retrieved from the University Digital Conservancy, https:/
University of Minnesota. Medical School Faculty Advisory Council
core  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Minutes: Medical School Faculty Advisory Council, Oct. 7, 2003

, 2003
Faculty advisory council to the Dean of the Medical School.University of Minnesota. Medical School Faculty Advisory Council. (2003). Minutes: Medical School Faculty Advisory Council, Oct. 7, 2003. Retrieved from the University Digital Conservancy, https:/
University of Minnesota. Medical School Faculty Advisory Council
core