Results 61 to 70 of about 21,448 (228)

Colorectal Cancer Screening in Hereditary and Familial High‐Risk Populations: Best Practices and Future Directions

International Journal of Cancer, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer‐related morbidity and mortality worldwide yet is largely preventable through effective screening and surveillance. While most CRC cases are sporadic, a substantial proportion occur in individuals at increased risk due to hereditary cancer syndromes or family history who require tailored
Ophir Gilad, Francesc Balaguer, Elizabeth E. Half, Kevin J. Monahan, Elena M. Stoffel, Sonia S. Kupfer   +5 more
wiley   +1 more source

Desmoid tumor mimicking cancer recurrence in a patient with colon cancer and Gardner syndrome: A case report

SAGE Open Medical Case Reports
Gardner syndrome, a subtype of familial adenomatous polyposis, features colorectal polyposis, osteomas and soft-tissue tumors with elevated colorectal carcinoma risk, and abdominal masses in these patients are easily misdiagnosed as malignant recurrence,
Jing Zhang, Yan Fu, Peng Zeng
doaj   +1 more source

Holistic bone developing microenvironment engineered apoptotic extracellular vesicles recapitulate multidimensional developmental signatures in adult and senile bone repair

Interdisciplinary Medicine, EarlyView.
The developing bone was identified as an M2a‐like macrophage driven immune microenvironment with multidimensional developmental signatures. hME‐ApoEVs were successfully fabricated via stimulating the M2a‐like developing microenvironment in vitro and confirmed its recapitulation of developmental features.
Xiaoran Yu, Jieyun Xu, Yuan Zhao, Xinyu Guo, Hongcheng Chen, Junlong Xue, Yong Ao, Linjun Zhang, Xiaomeng Gao, Xueli Mao, Songtao Shi, Zetao Chen   +11 more
wiley   +1 more source

Implication of adenomatous polyposis coli and MUTYH mutations in familial colorectal polyposis.

, 2009
PURPOSE: Familial adenomatous polyposis is an autosomal dominantly inherited syndrome characterized by hundreds or thousands of colorectal polyps and a high risk of colorectal cancer at a young age.
DURATURO, FRANCESCA, GALATOLA, MARTINA, MASONE, STEFANIA, Francesca Duraturo, Paola Izzo, DE ROSA, MARINA, Martina Galatola, Santa Borriello, Marina De Rosa, S. Borriello, IZZO, PAOLA, Stefania Masone   +11 more
core   +1 more source

Investigation of APC mutations in a Turkish familial adenomatous polyposis family by heterodublex analysis

, 2005
PURPOSE: Familial adenomatous polyposis is an autosomal dominant disease characterized by the presence of 100 or more colorectal adenomatous polyps. Mutations in the adenomatous polyposis coli gene are primarily responsible for the development of this ...
PEDRONI, Monica, U. Egeli, O. Yerci, PONZ DE LEON, Maurizio, M. Menigatti, B. Tunca, T. Yilmazlar, A. Scarselli, E. Sala, G. Cecener, BENATTI, Piero, A. Zorluoglu, F. Borghi   +12 more
core   +2 more sources

Endoscopic ischemic polypectomy for small intestinal polyps in a 7‐year‐old girl with juvenile polyposis syndrome

JPGN Reports, EarlyView.
Abstract This is the first report of endoscopic ischemic polypectomy (EIP) for small intestinal polyps in a pediatric patient with juvenile polyposis syndrome (JPS). A 7‐year‐old girl underwent double‐balloon enteroscopy, during which 17 pedunculated polyps were treated using the crossed‐clip strangulation method without complications. Ten‐month follow‐
Shingo Kurasawa, Shun Watanabe, Satoshi Ukai, Ayako Furuya, Kato Sawako, Yoshiko Nakayama   +5 more
wiley   +1 more source

The link between colon cancer and congenital hypertrophy of the retinal pigment epithelium (CHRPE)

American Journal of Ophthalmology Case Reports, 2019
Purpose: Clarify the differences between Familial Adenomatous Polyposis (FAP)-associated Congenital Hypertrophy of the Retinal Epithelium (CHRPE) and benign variants with regards to lesion characteristics and associated risk.
Brent Deibert, Letisha Ferris, Noel Sanchez, Paul Weishaar   +3 more
doaj   +1 more source

Demographic and Clinical Characteristics of Early‐Onset Colorectal Cancer in Sweden and Finland: A Multicentre Retrospective Cohort Study Over Three Decades

Journal of Surgical Oncology, EarlyView.
ABSTRACT Colorectal cancer is the third most common cancer worldwide, and the proportion of individuals diagnosed under the age of 50 years, referred to as early‐onset colorectal cancer (EOCRC), is increasing. The aim of this study was to evaluate how the demographic and clinical features of EOCR in northern Sweden and Finland have changed over time ...
Melina Charalambidi, Tanja Hukkinen, Tuomas Kaprio, Sofia Edin, Mats Hjortborg, Cecilia Williams, Jaana Hagström, Caj Haglund, Richard Palmqvist, Karin Strigård, Camilla Böckelman, Ioannis Gkekas   +11 more
wiley   +1 more source

Caracterització i identificació de les formes hereditàries de càncer colorectal [PDF]

, 2008
[cat] El càncer colorectal (CCR) és una de les neoplàsies més prevalents en els països occidentals, i un dels tumors en el que els factors genètics juguen un paper fonamental en el seu desenvolupament.
Balaguer Prunés, Francesc
core  

CD36 – a plausible modifier of disease phenotype in familial adenomatous polyposis

Hereditary Cancer in Clinical Practice, 2018
Background Familial adenomatous polyposis (FAP) is a well characterised genetic predisposition to early onset colorectal cancer (CRC) that is characterised by polyposis of the colon and rectum.
Merran Holmes, Toni Connor, Christopher Oldmeadow, Peter G. Pockney, Rodney J. Scott, Bente A. Talseth-Palmer   +5 more
doaj   +1 more source