Results 81 to 90 of about 21,448 (228)

The WHO Classification of Genetic Tumour Syndromes: Considerations for Genetics

Clinical Genetics, EarlyView.
The WHO Classification of Tumours underpins the diagnosis of neoplastic conditions. The new WHO classification of genetic tumour syndromes (GTS) provides international standards for their diagnosis. This diagram highlights the chromosomal distribution of the genes involved in the GTS covered in this classification.
Ian A. Cree, Mark J. Arends, Joseph D. Khoury, Erika R. E. Denton, Anthony J. Gill, Alexander J. Lazar, Ian M. Frayling, Stefan M. Pfister, Mark A. Rubin, Katia R. M. Leite, Raymond Dalgleish, Elspeth A. Bruford, Sharon E. Plon, Ada Hamosh, Michael Francis Walsh, Gabrielle Goldman‐Lévy, Harshima Wijesinghe, William D. Foulkes, Dilani Lokuhetty   +18 more
wiley   +1 more source

Adrenal Lesions in Patients With (Attenuated) Familial Adenomatous Polyposis and MUTYH-Associated Polyposis

, 2017
The reported proportion of patients with familial adenomatous polyposis who have adrenal lesions varies between 7% and 13% compared with 4% in the general population; the prevalence of adrenal lesions in patients with attenuated familial adenomatous ...
Patrick M.M. Bossuyt, Frank G.J. Kallenberg, Evelien Dekker, Barbara A.J. Bastiaansen, Bossuyt, Patrick M. M., Kallenberg, Frank G. J., Bastiaansen, Barbara A. J., Soeters, Maarten R., Aalfs, Cora M., C. Yung Nio, Boermeester, Marja A., Dekker, Evelien, Marja A. Boermeester, Nio, C. Yung, Maarten R. Soeters, Cora M. Aalfs   +15 more
core   +1 more source

Traditional serrated adenoma of the colorectum: Evolving concepts in histological classification and terminology

Histopathology, EarlyView.
The definition of the colorectal traditional serrated adenoma (TSA) has evolved to recognize a broader morphological spectrum, including classical, flat and mixed lesions reflecting early development and neoplastic progression. Updated WHO classification highlights the need for consistent terminology to improve recognition and to distinguish TSA from ...
Christophe Rosty, Maurice B. Loughrey, Taiki Hashimoto, Markus Mäkinen, Rish K. Pai, Shigeki Sekine, Rhonda K. Yantiss, Iris D. Nagtegaal   +7 more
wiley   +1 more source

A Rare Co-occurence of Acromegaly and Attenuated Familial Adenomatous Polyposis in a Young Patient: A Case Report and Review of Colonoscopy Screening Recommendations in Acromegaly

Endocrinology Research and Practice
Acromegaly raises the incidence of colorectal polyps, leading to recommendations for colonoscopy screening in these patients. Here, we present a case of a patient diagnosed with both acromegaly and multiple colon polyps.
Halil Durantas, Sema Hepsen, Ogulcan Boz, Hanife Saat, Harun Erdal, Erman Cakal   +5 more
doaj   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

The Initiation and Progression of Neoplasia in Inherited and Sporadic Colorectal Cancer.

, 2009
PhDThis dissertation describes investigations into aspects of neoplastic initiation and progression in the gut, in the context of inherited and sporadic gastrointestinal cancer. In familial adenomatous polyposis, there is marked locoregional variation
Will, Olivia Constance Claire
core  

Characterization of postnatal brain injury and behavioural deficits in a rat model of placental insufficiency‐induced fetal growth restriction

The Journal of Physiology, EarlyView.
Abstract figure legend Fetal growth restriction (FGR) is a common pregnancy complication associated with long‐term neurodevelopmental impairments. Using the reduced uterine perfusion pressure (RUPP) rat model of placental insufficiency‐induced FGR, this study demonstrates that FGR leads to persistent anatomical, histological and behavioural ...
Judit Alhama‐Riba, Caroline G. M. de Theije, Valentina Salvi, Dominique Viveen, Sebastiaan W. T. Corstjens, Marijke. E. J. Achterberg, Yohan van de Looij, Freek E. Hoebeek, Cora H. A. Nijboer   +8 more
wiley   +1 more source

Desmoid Fibromatosis of the Gastric Wall Mimicking Needle Tract Seeding after Endoscopic Ultrasound‐Guided Fine‐Needle Biopsy for Pancreatic Cancer: A Case Report

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Endoscopic ultrasound‐guided fine‐needle biopsy (EUS‐FNB) is widely used for the pathological diagnosis of pancreatic diseases. However, needle tract seeding (NTS) remains a clinical concern, particularly when the puncture route is not included in the surgical resection field. We report a case in which distinguishing NTS from other pathologies
Kazuya Koyama, Kenji Takahashi, Hidemasa Kawabata, Yusuke Ono, Nobue Tamamura, Tetsuhiro Okada, Hidetaka Iwamoto, Mishie Tanino, Mikihiro Fujiya, Yusuke Mizukami   +9 more
wiley   +1 more source

Improved Efficiency and Lesion Detection in Small Bowel Capsule Endoscopy Using the Open‐Source Artificial Intelligence Model SEE‐AI

DEN Open, Volume 7, Issue 1, April 2027.
AI‐assisted reading with the open‐source SEE‐AI model improves lesion detection sensitivity and reduces reading time in small‐bowel capsule endoscopy. In a multicenter retrospective study of 249 cases, SEE‐AI provides visual cues that support physicians during interpretation while preserving physician‐led final decisions.
Satoshi Miyazono, Junji Umeno, Tomohiro Nagasue, Takuto Saiki, Hisamitsu Kaku, Takehiro Torisu, Akihito Yokote, Keisuke Kawasaki, Yutaro Ihara, Yuichi Matsuno, Noriyuki Imazu, Tomohiko Moriyama, Ahmed Nashaat Mohamed, Katsuya Hirakawa, Hajime Yamagata, Yasuharu Okamoto, Koichi Kurahara, Shinichiro Yada, Akira Harada, Tetsuro Ago   +19 more
wiley   +1 more source

The mutation spectrum of the APC gene in Turkish patients with familial adenomatous polyposis

, 2007
Purpose: Familial adenomatous polyposis, an autosomal-dominant disease characterized by the presence of 100 or more colorectal adenomatous polyps, results from mutations in the adenomatous polyposis coli tumor suppressor gene.
Zorluoğlu, Abdullah
core   +1 more source